Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03831048 · ClinicalTrials.gov registry record · NA
Donors After Circulatory Death Heart Trial
A NA study of Heart Transplant, sponsored by TransMedics.
- Completed
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 20
- Study locations
NCT03831048: Completed NA study of Heart Transplant, sponsored by TransMedics.
NCT03831048 is a NA study of Heart Transplant that has completed, run by TransMedics. The registered enrollment target is 180 participants, below the 8,515-participant average among 12 other Heart Transplant trials with a reported enrollment target (98% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03831048, a NA study of Heart Transplant, has completed, sponsored by TransMedics.
- COMPLETED
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 20
- Study locations
Study Summary
To evaluate the effectiveness of the OCS Heart System to resuscitate, preserve and assess hearts donated after circulatory death for transplantation to increase the pool of donor hearts available for transplantation.
Primary Outcome
Patient survival 6 months post-transplant
Conditions Studied
Interventions
- DEVICE OCS Heart System
- OTHER Cold Storage
Study Locations (20)
California
- University of California San Diago - La Jolla
- Cedars Sinai - Los Angeles
- Stanford University - Palo Alto
Florida
- Mayo Clinic Florida - Jacksonville
- AdventHealth - Orlando
- Tampa General Hospital - Tampa
Massachusetts
- Tufts Medical Center - Boston
- Massachusetts General Hospital - Boston
- Brigham and Women's Hospital - Boston
New York
- Nyph/Cumc - New York
- Montefiore - The Bronx
- Westchester Medical Center - Valhalla
Minnesota
- Minneapolis Heart Institute - Minneapolis
- University of Minnesota - Minneapolis
Connecticut
- Yale New Haven Hospital - New Haven
Georgia
- Emory University Hospital - Atlanta
Illinois
- Northwestern Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2019-11-26 |
| Est. Completion | 2021-09-28 |
| Phase | NA |
What the finished NCT03831048 record still lists
NCT03831048 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 8,515-participant average among 12 other Heart Transplant trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Heart Transplant appearing as the primary indexed condition, and to 2 interventions - of which OCS Heart System is the first listed.
NCT03831048 names 20 study sites across 11 states, led by California, Florida, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03831048 about?
NCT03831048 is a clinical study titled "Donors After Circulatory Death Heart Trial". To evaluate the effectiveness of the OCS Heart System to resuscitate, preserve and assess hearts donated after circulatory death for transplantation to increase the pool of donor hearts available for transplantation.
What is the current status of trial NCT03831048?
This trial is currently completed. It is a NA study. The enrollment target is 180 participants. The study started on 2019-11-26. Estimated completion is 2021-09-28.
What conditions does trial NCT03831048 study?
This clinical trial studies the following conditions: Heart Transplant.
What interventions are being tested in trial NCT03831048?
The interventions under investigation include: OCS Heart System (DEVICE), Cold Storage (OTHER).
Who is sponsoring clinical trial NCT03831048?
This trial is sponsored by TransMedics, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03831048 being conducted?
This trial has 20 study locations across California, Connecticut, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03831048's enrollment target sits among peer trials
180 6th of 12 higher than 7 of 12 other Heart Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
RECRUITING · NA
-
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
RECRUITING · NA
-
Enhancing Heart Allograft Function With the OCS Heart System Trial
RECRUITING · NA
-
Heart EXPAND Continued Access Protocol
COMPLETED · NA
-
International EXPAND Heart Pivotal Trial
COMPLETED · NA
-
US National OCS Heart Perfusion (OHP) Registry
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01558804 · 180 participants
GRoup A StrePtococcus
- NCT02932176 · 180 participants
Machine Learning for Handheld Vascular Studies
- NCT03384563 · 180 participants · Phase 4
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
- NCT03423628 · 180 participants · Phase 1
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI