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ClinicalTrials.gov 3 recruiting now full pipeline small index

Actinic Keratoses: full-pipeline trial registry

3 of 13 indexed Actinic Keratoses trials are currently recruiting.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 3 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Actinic Keratoses: 13 US clinical trials tracked, 3 recruiting.

Actinic Keratoses is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Wright State University, running 2 of these trials.

Enrollment posture brief

Registry condition actinic-keratoses

OPEN 3 | RECR 23% | LATE 4 | EARLY 3 | RANK #1315 | SPON 2

Nearest open-share peer: Endometrial Serous Adenocarcinoma (23% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Acute Decompensated Heart Fa30.8%Actinic Keratoses (this)23%
Open-enrollment share among volume-matched conditions near Actinic Keratoses

Actinic Keratoses lists 3 open slots (23% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Actinic Keratoses on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Actinic Keratoses is recruiting below its size-band peers.

    3 of 13 indexed trials (23.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Actinic Keratoses research.

    Wright State University accounts for 2 of 13 trials (15.4%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Actinic Keratoses trials plan to enrol fewer than 100 people.

    Median target enrolment is 44 among the 13 trials that report a genuine target (sentinel values excluded). 11 of those (84.6%) plan for fewer than 100 participants.

  4. Actinic Keratoses research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 32Phase 42

Open and recent trials

13 total, page 1 of 1

RECRUITING NA 80 participants

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Wright State University

NCT06428721

RECRUITING NA 72 participants

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Wright State University

NCT03906253

RECRUITING Phase 4 40 participants

Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face

Psoriasis Treatment Center of Central New Jersey

NCT06745999

ACTIVE NOT RECRUITING Phase 3 172 participants

Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp

Biofrontera

NCT05662202

ACTIVE NOT RECRUITING NA 60 participants

Photodynamic Therapy Incubation Times for Actinic Keratosis

Northwestern University

NCT03066843

COMPLETED Phase 3 557 participants

Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face

Galderma R&D

NCT04085367

COMPLETED Phase 1 48 participants

Study to Evaluate the Safety of BF-200 ALA (Ameluz®) for Photodynamic Therapy (PDT) in the Treatment of Expanded Fields of Actinic Keratosis (AK)

Biofrontera Bioscience

NCT04319159

COMPLETED NA 44 participants

Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video

University of California, Davis

NCT02062853

COMPLETED Phase 4 30 participants

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents

University of Arizona

NCT03279328

COMPLETED Phase 1 24 participants

Daylight Photodynamic Therapy for Actinic Keratosis

University of California, San Francisco

NCT03322293

COMPLETED NA 20 participants

A Clinical Trial Evaluating the Role of Systemic Antihistamine Therapy in the Reduction of Adverse Effects Associated With Topical 5-aminolevulinic Acid Photodynamic Therapy

Goldman, Butterwick, Fitzpatrick and Groff

NCT02451579

COMPLETED NA 20 participants

A Photodynamic Therapy for Treatment of Actinic Keratoses

Northwestern University

NCT00558688

COMPLETED Phase 1 10 participants

Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

Sherrif Ibrahim

NCT07053852

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 3 2
Phase 4 2

Named interventions

Most-linked intervention names on Actinic Keratoses records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

BF-200 ALA and red light LED lamp Combination
2 trials
Fractionated Laser Resurfacing Device
2 trials
MAL Vehicle Cream Drug
1 trials
MAL 16.8% cream Drug
1 trials
Sciton HEROic Device
1 trials
Ameluz Drug
1 trials
Photodynamic therapy Procedure
1 trials
BLU-U blue light phototherapy illuminator Device
1 trials

US sites by state

Facility locations filed on Actinic Keratoses trials. A trial with sites in several states counts in each.

California 4 trials
Arizona 3 trials
Texas 2 trials
Ohio 2 trials
New York 2 trials
Illinois 2 trials
Georgia 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Actinic Keratoses page

13 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Actinic Keratoses condition card totals 13 registered trials; most-linked intervention BF-200 ALA and red light LED lamp; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.