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ClinicalTrials.gov 3 recruiting now official registry

Actinic Keratoses clinical trials

3 of 13 indexed Actinic Keratoses trials are currently recruiting.

13 US clinical trials · 3 currently recruiting

Actinic Keratoses is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Wright State University, running 2 of these trials.

The research picture

Actinic Keratoses has 13 registered US clinical trials, 3 of them open to new participants right now, about 23% of the total.

3
recruiting participants now
23%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
2
top sponsor: Wright State University
Phase 13Phase 32Phase 42

Active & Recent Trials

13 total, page 1 of 1

RECRUITING NA 80 participants

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Wright State University

NCT06428721

RECRUITING NA 72 participants

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Wright State University

NCT03906253

RECRUITING Phase 4 40 participants

Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face

Psoriasis Treatment Center of Central New Jersey

NCT06745999

ACTIVE NOT RECRUITING Phase 3 172 participants

Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp

Biofrontera

NCT05662202

ACTIVE NOT RECRUITING NA 60 participants

Photodynamic Therapy Incubation Times for Actinic Keratosis

Northwestern University

NCT03066843

COMPLETED Phase 3 557 participants

Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face

Galderma R&D

NCT04085367

COMPLETED Phase 1 48 participants

Study to Evaluate the Safety of BF-200 ALA (Ameluz®) for Photodynamic Therapy (PDT) in the Treatment of Expanded Fields of Actinic Keratosis (AK)

Biofrontera Bioscience

NCT04319159

COMPLETED NA 44 participants

Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video

University of California, Davis

NCT02062853

COMPLETED Phase 4 30 participants

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents

University of Arizona

NCT03279328

COMPLETED Phase 1 24 participants

Daylight Photodynamic Therapy for Actinic Keratosis

University of California, San Francisco

NCT03322293

COMPLETED NA 20 participants

A Clinical Trial Evaluating the Role of Systemic Antihistamine Therapy in the Reduction of Adverse Effects Associated With Topical 5-aminolevulinic Acid Photodynamic Therapy

Goldman, Butterwick, Fitzpatrick and Groff

NCT02451579

COMPLETED NA 20 participants

A Photodynamic Therapy for Treatment of Actinic Keratoses

Northwestern University

NCT00558688

COMPLETED Phase 1 10 participants

Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

Sherrif Ibrahim

NCT07053852

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 3 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Actinic Keratoses Trial Landscape

13 indexed Actinic Keratoses studies · 3 recruiting (23%).

Phase mix: 4 late (III/IV) vs 3 early (I/II).

Top sponsor: Wright State University (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Actinic Keratoses?

PlainTrial tracks 13 US clinical trials for Actinic Keratoses, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Actinic Keratoses?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.