Natera
Natera sponsors 27 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 14 completed. 1 of these trials are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Trisomy 13, with 3 trials.
Trial Pipeline
27 total, page 1 of 1
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
NCT07214532
Sample Collection for Ongoing Research and Product Evaluation Study
NCT07318051
Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)
NCT07046585
Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection
NCT06620627
EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)
NCT06808880
A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy
NCT06414603
LAMBDA 002 (Lung Registry) Study
NCT05170425
Prospera Test Evaluation in Cardiac Transplant (ProTECT)
NCT05205551
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984
Signatera Assessment in Early-Stage Endometrial Cancer
NCT07339384
Development of Non-invasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation
NCT05309382
Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.
NCT05312814
Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies
NCT05004337
BESPOKE Study of ctDNA Guided Immunotherapy
NCT04761783
Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection
NCT03984747
Natera Ovarian Cancer Detection Assay
NCT03485651
SNP-based Microdeletion and Aneuploidy RegisTry (SMART)
NCT02381457
High Risk Multiple Gestation Study
NCT02278874
Multiple Gestation Study
NCT02278536
Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood
NCT01852708
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
NCT02109770
Collection of Maternal Blood Samples for Development of Non-invasive Prenatal Diagnostic Testing
NCT01546324
Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
NCT01545674
Non-invasive Prenatal Diagnostic Validation Study
NCT01574781
Clinical Use of Parental Support To Detect Single Gene Mutations
NCT01197872
Impact of Parental Support on Pregnancy Outcomes (IPSO) Trial- Day 3 Preimplantation Genetic Screening (PGS) With Day 5 Fresh Transfer
NCT01194531
Concurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD)
NCT01023048
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
What the Pipeline for Natera Shows
According to the ClinicalTrials.gov registry, Natera is linked to 27 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting, about 19% of the sponsor's indexed portfolio, and 14 are already marked complete, representing roughly 52% of the total.
The phase mix for Natera reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Natera is Trisomy 13 with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.