Natera

27 total trials 5 currently recruiting 14 completed

Natera sponsors 27 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 14 completed. 1 of these trials are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Trisomy 13, with 3 trials.

Trial Pipeline

27 total, page 1 of 1

RECRUITING NA

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

NCT07214532

RECRUITING

Sample Collection for Ongoing Research and Product Evaluation Study

NCT07318051

RECRUITING

Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)

NCT07046585

RECRUITING

Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection

NCT06620627

RECRUITING

EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)

NCT06808880

ACTIVE NOT RECRUITING NA

A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy

NCT06414603

ACTIVE NOT RECRUITING

LAMBDA 002 (Lung Registry) Study

NCT05170425

ACTIVE NOT RECRUITING

Prospera Test Evaluation in Cardiac Transplant (ProTECT)

NCT05205551

ACTIVE NOT RECRUITING

The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)

NCT04091984

NOT YET RECRUITING NA

Signatera Assessment in Early-Stage Endometrial Cancer

NCT07339384

COMPLETED

Development of Non-invasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation

NCT05309382

COMPLETED

Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.

NCT05312814

COMPLETED

Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies

NCT05004337

COMPLETED

BESPOKE Study of ctDNA Guided Immunotherapy

NCT04761783

COMPLETED

Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection

NCT03984747

TERMINATED

Natera Ovarian Cancer Detection Assay

NCT03485651

COMPLETED

SNP-based Microdeletion and Aneuploidy RegisTry (SMART)

NCT02381457

COMPLETED

High Risk Multiple Gestation Study

NCT02278874

COMPLETED

Multiple Gestation Study

NCT02278536

COMPLETED

Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood

NCT01852708

COMPLETED

Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA

NCT02109770

COMPLETED

Collection of Maternal Blood Samples for Development of Non-invasive Prenatal Diagnostic Testing

NCT01546324

TERMINATED

Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial

NCT01545674

COMPLETED

Non-invasive Prenatal Diagnostic Validation Study

NCT01574781

COMPLETED

Clinical Use of Parental Support To Detect Single Gene Mutations

NCT01197872

TERMINATED Phase 4

Impact of Parental Support on Pregnancy Outcomes (IPSO) Trial- Day 3 Preimplantation Genetic Screening (PGS) With Day 5 Fresh Transfer

NCT01194531

COMPLETED NA

Concurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD)

NCT01023048

What the Pipeline for Natera Shows

According to the ClinicalTrials.gov registry, Natera is linked to 27 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting, about 19% of the sponsor's indexed portfolio, and 14 are already marked complete, representing roughly 52% of the total.

The phase mix for Natera reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Natera is Trisomy 13 with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.