Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Healthy Participants: early-phase trial registry
42 of 120 indexed Healthy Participants trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #104 of 28,707 conditions by registered trial count.
120 US clinical trials · 42 currently recruiting · #104 of 28,707 conditions by registered trial count
Healthy Participants: 120 US clinical trials tracked, 42 recruiting.
Healthy Participants is the subject of 120 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 100 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 18 of these trials.
Enrollment posture brief
Registry condition healthy-participants
OPEN 42 | RECR 35% | LATE 1 | EARLY 100 | RANK #104 | SPON 18
Volume-matched condition peers
Nearest open-share peer: Anatomic Stage IIIA Breast Cancer AJCC v8 (35% recruiting · 40 trials)
Healthy Participants lists 42 open slots (35% of 120 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Participants on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Healthy Participants is recruiting below its size-band peers.
42 of 120 indexed trials (35%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Healthy Participants research.
AstraZeneca accounts for 18 of 120 trials (15%). 54 distinct sponsors appear on at least one study for this condition label.
-
Most Healthy Participants trials plan to enrol fewer than 100 people.
Median target enrolment is 40 among the 120 trials that report a genuine target (sentinel values excluded). 96 of those (80%) plan for fewer than 100 participants.
-
Healthy Participants research is mostly interventional.
116 interventional and 4 observational studies make up this index (96.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
120 total, page 2 of 3
Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24)
Arcus Biosciences
NCT07364214
An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab
AstraZeneca
NCT06908577
A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants
Bristol-Myers Squibb
NCT04175925
A Study to Compare the Pharmacokinetics of CSL312 Administered by Prefilled Syringe Assembled to Autoinjector to the Pharmacokinetics Administered by Prefilled Syringe Assembled to Needle Safety Device in Healthy Subjects
CSL Behring
NCT05306275
A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants
Incyte Corporation
NCT06441318
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-994 in Healthy Participants
Takeda
NCT03933488
A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants
AstraZeneca
NCT06138795
A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults
Pfizer
NCT05923411
Relative Levels of BMS-986036 in Blood Plasma in Healthy, Overweight, and Obese Participants Following Subcutaneous Administration Via Auto-injector Versus Pre-filled Syringe
Bristol-Myers Squibb
NCT04493567
Study of BLU-808 in Healthy Adult Participants
Blueprint Medicines Corporation
NCT06948032
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants
AstraZeneca
NCT06491550
A Study to Evaluate the Effects of Mavacamten in Healthy Participants
Bristol-Myers Squibb
NCT05719805
An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram Effects
Bristol-Myers Squibb
NCT03541564
A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants
Cerevel Therapeutics
NCT05138653
A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
Bristol-Myers Squibb
NCT05901714
A Study of TAK-071 in People With Parkinson Disease
Takeda
NCT04334317
A Study Investigating Lu AG22515 in Healthy Adults
H. Lundbeck A/S
NCT05136053
A Study to Assess the Effect of Food on the Drug Levels of Admilparant
Bristol-Myers Squibb
NCT07225647
A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity
Celgene
NCT06411730
Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants
Janssen Scientific Affairs
NCT01464450
A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy Participants
UCB Biopharma SRL
NCT07020988
A Study of Different Forms of TAK-994 in Healthy Adults
Takeda
NCT04745767
A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants
Takeda
NCT03083639
Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986331 in Healthy Participants
Bristol-Myers Squibb
NCT04444050
Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects
Bridge Biotherapeutics
NCT04138836
A Study to Assess New Formulations of TEV-56286
Teva Branded Pharmaceutical Products R&D
NCT06911567
A Study to Compare the Drug Levels of Atazanavir and Cobicistat Between the Coadministration of Age-Appropriate Mini-Tablet Formulations and the Coadministration of the Individual Reference Products in Healthy Adults Under Fed Conditions
Bristol-Myers Squibb
NCT05236738
A Study to Assess the Safety, Tolerability and Drug Levels of BMS-986172 in Healthy and Obese Participants, Including an Assessment of the Effects of Food on BMS-986172 Absorption
Bristol-Myers Squibb
NCT04926051
A Study to Investigate the Safety and Pharmacokinetics of AZD6793 in Healthy Japanese and Chinese Participants
AstraZeneca
NCT06368440
A Study to Characterize Single and Repeat Dose Pharmacokinetics of Tebipenem-Pivoxil-Hydrobromide (TBP-PI-HBr) and Its Major Metabolite (SPR1349) in Healthy Participants
Spero Therapeutics
NCT06727136
Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 in Japanese and Chinese Healthy Volunteers..
AstraZeneca
NCT05955183
A Study to Investigate the Relative Bioavailability of AZD8630 Following a Device and Formulation Transition in Healthy Participants.
AstraZeneca
NCT06531811
A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of a Single Dose of Donzakimig in Healthy Chinese and Japanese Participants
UCB Biopharma SRL
NCT06716879
A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants
Celgene
NCT06170723
A Study TO Learn HOW THE Study Medicine Called PF-07293893 Affects Muscle Biomarkers OF Healthy Adults
Pfizer
NCT06413693
Washington University WU 409: Immune Responses to Rabies Vaccine.
Washington University School of Medicine
NCT07399951
A Study of Single Ascending Doses of PF-07258669 in Healthy Adult Participants
Pfizer
NCT04628793
A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants
Pfizer
NCT05067439
A Study to Characterize the Drug Levels of an Oral Contraceptive With and Without BMS-986166 in Healthy Female Participants of Childbearing Potential
Bristol-Myers Squibb
NCT04934696
A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JZP441 in Healthy Participants
Jazz Pharmaceuticals
NCT05720494
PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants
Pfizer
NCT05064800
Evaluate Safety, Pharmacokinetics and Pharmacodynamics of BBT-877 in Healthy Japanese Male
Bridge Biotherapeutics
NCT04138849
A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants
Arcus Biosciences
NCT05277012
SP16 SERPIN-like Peptide Administration in Healthy Individuals
Serpin Pharma
NCT03651089
A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants
Insmed Incorporated
NCT06344728
Cognitive Conditioned Pain Modulation
University of Washington
NCT07234123
A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose
Novo Nordisk A/S
NCT05689099
A Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants
Genentech
NCT06835465
A Study to Evaluate the Food-Effect of H3B-6527
Eisai
NCT03424577
Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone
Sparrow Pharmaceuticals
NCT07226635
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 98 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Participants records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Participants trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Participants page
120 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 42 Healthy Participants trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- AstraZeneca sponsors the most Healthy Participants trials on record, review their full trial history before evaluating a specific study. See AstraZeneca's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Participants condition card totals 120 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.