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ClinicalTrials.gov 42 recruiting now official registry

Healthy Participants clinical trials

42 of 120 indexed Healthy Participants trials are currently recruiting.

120 US clinical trials · 42 currently recruiting

Healthy Participants is the subject of 120 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 100 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 18 of these trials.

The research picture

Healthy Participants has 120 registered US clinical trials, 42 of them open to new participants right now, about 35% of the total.

42
recruiting participants now
35%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
18
top sponsor: AstraZeneca
Phase 198Phase 22Phase 31

Active & Recent Trials

120 total, page 2 of 3

ACTIVE NOT RECRUITING Phase 1 8 participants

Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24)

Arcus Biosciences

NCT07364214

COMPLETED Phase 1 254 participants

An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab

AstraZeneca

NCT06908577

COMPLETED Phase 1 171 participants

A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants

Bristol-Myers Squibb

NCT04175925

COMPLETED Phase 1 132 participants

A Study to Compare the Pharmacokinetics of CSL312 Administered by Prefilled Syringe Assembled to Autoinjector to the Pharmacokinetics Administered by Prefilled Syringe Assembled to Needle Safety Device in Healthy Subjects

CSL Behring

NCT05306275

COMPLETED Phase 1 128 participants

A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants

Incyte Corporation

NCT06441318

COMPLETED Phase 1 121 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-994 in Healthy Participants

Takeda

NCT03933488

COMPLETED Phase 1 120 participants

A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants

AstraZeneca

NCT06138795

COMPLETED Phase 1 113 participants

A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Pfizer

NCT05923411

COMPLETED Phase 1 102 participants

Relative Levels of BMS-986036 in Blood Plasma in Healthy, Overweight, and Obese Participants Following Subcutaneous Administration Via Auto-injector Versus Pre-filled Syringe

Bristol-Myers Squibb

NCT04493567

COMPLETED Phase 1 95 participants

Study of BLU-808 in Healthy Adult Participants

Blueprint Medicines Corporation

NCT06948032

COMPLETED Phase 1 91 participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants

AstraZeneca

NCT06491550

COMPLETED Phase 1 84 participants

A Study to Evaluate the Effects of Mavacamten in Healthy Participants

Bristol-Myers Squibb

NCT05719805

COMPLETED Phase 1 84 participants

An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram Effects

Bristol-Myers Squibb

NCT03541564

COMPLETED Phase 1 73 participants

A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants

Cerevel Therapeutics

NCT05138653

COMPLETED Phase 1 65 participants

A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam

Bristol-Myers Squibb

NCT05901714

COMPLETED Phase 2 64 participants

A Study of TAK-071 in People With Parkinson Disease

Takeda

NCT04334317

COMPLETED Phase 1 58 participants

A Study Investigating Lu AG22515 in Healthy Adults

H. Lundbeck A/S

NCT05136053

COMPLETED Phase 1 56 participants

A Study to Assess the Effect of Food on the Drug Levels of Admilparant

Bristol-Myers Squibb

NCT07225647

COMPLETED Phase 1 56 participants

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Celgene

NCT06411730

COMPLETED Phase 1 55 participants

Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants

Janssen Scientific Affairs

NCT01464450

COMPLETED Phase 1 55 participants

A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy Participants

UCB Biopharma SRL

NCT07020988

COMPLETED Phase 1 54 participants

A Study of Different Forms of TAK-994 in Healthy Adults

Takeda

NCT04745767

COMPLETED Phase 1 52 participants

A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants

Takeda

NCT03083639

COMPLETED Phase 1 48 participants

Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986331 in Healthy Participants

Bristol-Myers Squibb

NCT04444050

COMPLETED Phase 1 48 participants

Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects

Bridge Biotherapeutics

NCT04138836

COMPLETED Phase 1 47 participants

A Study to Assess New Formulations of TEV-56286

Teva Branded Pharmaceutical Products R&D

NCT06911567

COMPLETED Phase 1 42 participants

A Study to Compare the Drug Levels of Atazanavir and Cobicistat Between the Coadministration of Age-Appropriate Mini-Tablet Formulations and the Coadministration of the Individual Reference Products in Healthy Adults Under Fed Conditions

Bristol-Myers Squibb

NCT05236738

COMPLETED Phase 1 40 participants

A Study to Assess the Safety, Tolerability and Drug Levels of BMS-986172 in Healthy and Obese Participants, Including an Assessment of the Effects of Food on BMS-986172 Absorption

Bristol-Myers Squibb

NCT04926051

COMPLETED Phase 1 39 participants

A Study to Investigate the Safety and Pharmacokinetics of AZD6793 in Healthy Japanese and Chinese Participants

AstraZeneca

NCT06368440

COMPLETED Phase 1 39 participants

A Study to Characterize Single and Repeat Dose Pharmacokinetics of Tebipenem-Pivoxil-Hydrobromide (TBP-PI-HBr) and Its Major Metabolite (SPR1349) in Healthy Participants

Spero Therapeutics

NCT06727136

COMPLETED Phase 1 38 participants

Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 in Japanese and Chinese Healthy Volunteers..

AstraZeneca

NCT05955183

COMPLETED Phase 1 32 participants

A Study to Investigate the Relative Bioavailability of AZD8630 Following a Device and Formulation Transition in Healthy Participants.

AstraZeneca

NCT06531811

COMPLETED Phase 1 32 participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of a Single Dose of Donzakimig in Healthy Chinese and Japanese Participants

UCB Biopharma SRL

NCT06716879

COMPLETED Phase 1 32 participants

A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants

Celgene

NCT06170723

COMPLETED Phase 1 31 participants

A Study TO Learn HOW THE Study Medicine Called PF-07293893 Affects Muscle Biomarkers OF Healthy Adults

Pfizer

NCT06413693

COMPLETED Early Phase 1 30 participants

Washington University WU 409: Immune Responses to Rabies Vaccine.

Washington University School of Medicine

NCT07399951

COMPLETED Phase 1 29 participants

A Study of Single Ascending Doses of PF-07258669 in Healthy Adult Participants

Pfizer

NCT04628793

COMPLETED Phase 1 26 participants

A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants

Pfizer

NCT05067439

COMPLETED Phase 1 25 participants

A Study to Characterize the Drug Levels of an Oral Contraceptive With and Without BMS-986166 in Healthy Female Participants of Childbearing Potential

Bristol-Myers Squibb

NCT04934696

COMPLETED Phase 1 24 participants

A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JZP441 in Healthy Participants

Jazz Pharmaceuticals

NCT05720494

COMPLETED Phase 1 24 participants

PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants

Pfizer

NCT05064800

COMPLETED Phase 1 24 participants

Evaluate Safety, Pharmacokinetics and Pharmacodynamics of BBT-877 in Healthy Japanese Male

Bridge Biotherapeutics

NCT04138849

COMPLETED Phase 1 24 participants

A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants

Arcus Biosciences

NCT05277012

COMPLETED Phase 1 24 participants

SP16 SERPIN-like Peptide Administration in Healthy Individuals

Serpin Pharma

NCT03651089

COMPLETED Phase 1 24 participants

A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants

Insmed Incorporated

NCT06344728

COMPLETED NA 24 participants

Cognitive Conditioned Pain Modulation

University of Washington

NCT07234123

COMPLETED Phase 1 20 participants

A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose

Novo Nordisk A/S

NCT05689099

COMPLETED Phase 1 18 participants

A Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants

Genentech

NCT06835465

COMPLETED Phase 1 17 participants

A Study to Evaluate the Food-Effect of H3B-6527

Eisai

NCT03424577

COMPLETED Phase 1 16 participants

Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone

Sparrow Pharmaceuticals

NCT07226635

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Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 2
Phase 3 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Healthy Participants Trial Landscape

120 indexed Healthy Participants studies · 42 recruiting (35%).

Phase mix: 1 late (III/IV) vs 100 early (I/II).

Top sponsor: AstraZeneca (18 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Healthy Participants?

PlainTrial tracks 120 US clinical trials for Healthy Participants, of which 42 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Healthy Participants?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.