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Healthy Participants clinical trials
42 of 120 indexed Healthy Participants trials are currently recruiting.
120 US clinical trials · 42 currently recruiting
Healthy Participants is the subject of 120 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 100 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 18 of these trials.
The research picture
Healthy Participants has 120 registered US clinical trials, 42 of them open to new participants right now, about 35% of the total.
- 42
- recruiting participants now
- 35%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 18
- top sponsor: AstraZeneca
Active & Recent Trials
120 total, page 3 of 3
A Study in Healthy Participants to Investigate Relative Bioavailability of AZD5004 in Three Solid Oral Formulations
AstraZeneca
NCT06996886
A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants
AstraZeneca
NCT06973005
A Study of LY2409021 in Healthy Participants
Eli Lilly and Company
NCT02217618
The Effective of Immersive Virtual Reality Distraction on Memory: Study 1
University of Washington
NCT07172230
A Study to Investigate the Pharmacokinetics of AZD2389 When Administered Alone and in Combination With Itraconazole in Healthy Participants
AstraZeneca
NCT06846528
A Study to Investigate the Effects of Cytochrome P450 1A2 Induction by Ritonavir on BMS-986165 Drug Levels and Effects in Healthy Participants
Bristol-Myers Squibb
NCT04055506
A Bioavailability and Food Effect Study of AZD5462 in Healthy Volunteers
AstraZeneca
NCT05512806
Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants
Pfizer
NCT05525910
A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants
AstraZeneca
NCT06357520
Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration
Vanderbilt University
NCT01064739
Study to Evaluate the Effect of AMG 510 on the Pharmacokinetics (PK) of Digoxin in Healthy Participants
Amgen
NCT05598281
Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants
Amgen
NCT05045638
A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants
Amgen
NCT05571163
Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study
Rutgers, The State University of New Jersey
NCT07151235
A Study to Assess the Effects of BPN14770 on Rosuvastatin
Shionogi
NCT07011992
Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants
Pfizer
NCT05129475
A Taste Assessment of Iberdomide and Mezigdomide in Healthy Participants
Bristol-Myers Squibb
NCT05539976
Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB123667 in Healthy Male Participants
Incyte Corporation
NCT07218744
A Study to Assess Mass Balance, Pharmacokinetics, Metabolism, and Excretion of Emraclidine in Healthy Adult Male Participants
Cerevel Therapeutics
NCT06301971
A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants
Bristol-Myers Squibb
NCT05567510
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 98 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Healthy Participants Trial Landscape
120 indexed Healthy Participants studies · 42 recruiting (35%).
Phase mix: 1 late (III/IV) vs 100 early (I/II).
Top sponsor: AstraZeneca (18 trials), 9 others listed. 20 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Healthy Participants?
PlainTrial tracks 120 US clinical trials for Healthy Participants, of which 42 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Healthy Participants?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.