Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Healthy Participants: early-phase trial registry
42 of 120 indexed Healthy Participants trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #104 of 28,707 conditions by registered trial count.
120 US clinical trials · 42 currently recruiting · #104 of 28,707 conditions by registered trial count
Healthy Participants: 120 US clinical trials tracked, 42 recruiting.
Healthy Participants is the subject of 120 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 100 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 18 of these trials.
Enrollment posture brief
Registry condition healthy-participants
OPEN 42 | RECR 35% | LATE 1 | EARLY 100 | RANK #104 | SPON 18
Volume-matched condition peers
Nearest open-share peer: Anatomic Stage IIIA Breast Cancer AJCC v8 (35% recruiting · 40 trials)
Healthy Participants lists 42 open slots (35% of 120 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Participants on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Healthy Participants is recruiting below its size-band peers.
42 of 120 indexed trials (35%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Healthy Participants research.
AstraZeneca accounts for 18 of 120 trials (15%). 54 distinct sponsors appear on at least one study for this condition label.
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Most Healthy Participants trials plan to enrol fewer than 100 people.
Median target enrolment is 40 among the 120 trials that report a genuine target (sentinel values excluded). 96 of those (80%) plan for fewer than 100 participants.
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Healthy Participants research is mostly interventional.
116 interventional and 4 observational studies make up this index (96.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
120 total, page 3 of 3
A Study in Healthy Participants to Investigate Relative Bioavailability of AZD5004 in Three Solid Oral Formulations
AstraZeneca
NCT06996886
A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants
AstraZeneca
NCT06973005
A Study of LY2409021 in Healthy Participants
Eli Lilly and Company
NCT02217618
The Effective of Immersive Virtual Reality Distraction on Memory: Study 1
University of Washington
NCT07172230
A Study to Investigate the Pharmacokinetics of AZD2389 When Administered Alone and in Combination With Itraconazole in Healthy Participants
AstraZeneca
NCT06846528
A Study to Investigate the Effects of Cytochrome P450 1A2 Induction by Ritonavir on BMS-986165 Drug Levels and Effects in Healthy Participants
Bristol-Myers Squibb
NCT04055506
A Bioavailability and Food Effect Study of AZD5462 in Healthy Volunteers
AstraZeneca
NCT05512806
Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants
Pfizer
NCT05525910
A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants
AstraZeneca
NCT06357520
Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration
Vanderbilt University
NCT01064739
Study to Evaluate the Effect of AMG 510 on the Pharmacokinetics (PK) of Digoxin in Healthy Participants
Amgen
NCT05598281
Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants
Amgen
NCT05045638
A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants
Amgen
NCT05571163
Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study
Rutgers, The State University of New Jersey
NCT07151235
A Study to Assess the Effects of BPN14770 on Rosuvastatin
Shionogi
NCT07011992
Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants
Pfizer
NCT05129475
A Taste Assessment of Iberdomide and Mezigdomide in Healthy Participants
Bristol-Myers Squibb
NCT05539976
Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB123667 in Healthy Male Participants
Incyte Corporation
NCT07218744
A Study to Assess Mass Balance, Pharmacokinetics, Metabolism, and Excretion of Emraclidine in Healthy Adult Male Participants
Cerevel Therapeutics
NCT06301971
A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants
Bristol-Myers Squibb
NCT05567510
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 98 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Participants records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Participants trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Participants page
120 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 42 Healthy Participants trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- AstraZeneca sponsors the most Healthy Participants trials on record, review their full trial history before evaluating a specific study. See AstraZeneca's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Participants condition card totals 120 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.