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NCT06441318 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants
A Phase 1 study of Healthy Participants, sponsored by Incyte Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 128
- Enrollment target
- 1
- Study location
NCT06441318: Completed Phase 1 study of Healthy Participants, sponsored by Incyte Corporation.
NCT06441318 is a Phase 1 study of Healthy Participants that has completed, run by Incyte Corporation. The registered enrollment target is 128 participants, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (97% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06441318, a Phase 1 study of Healthy Participants, has completed, sponsored by Incyte Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 128 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the effect of povorcitinib on the QT/QTc Interval in healthy participants.
Primary Outcome
Electrocardiogram measurement of the maximum absolute change from baseline in Fridericia's correction for QT interval (QTcF)
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Povorcitinib
- DRUG Moxifloxacin
Study Locations (1)
Arizona
- Celerion Clinical Research Unit - Tempe
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2024-07-12 |
| Est. Completion | 2024-09-10 |
| Phase | Phase 1 |
What the finished NCT06441318 record still lists
NCT06441318 is an interventional study that assigns participants to a tested intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (97% higher).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT06441318 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT06441318 about?
NCT06441318 is a clinical study titled "A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants". The purpose of this study is to evaluate the effect of povorcitinib on the QT/QTc Interval in healthy participants.
What is the current status of trial NCT06441318?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 128 participants. The study started on 2024-07-12. Estimated completion is 2024-09-10.
What conditions does trial NCT06441318 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT06441318?
The interventions under investigation include: Placebo (DRUG), Povorcitinib (DRUG), Moxifloxacin (DRUG).
Who is sponsoring clinical trial NCT06441318?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06441318 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06441318's enrollment target sits among peer trials
128 13th of 119 higher than 107 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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