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NCT06908577 · ClinicalTrials.gov registry record · Phase 1

An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab

A Phase 1 study of Healthy Participants, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
254
Enrollment target
4
Study locations

NCT06908577 is a Phase 1 study of Healthy Participants that has completed, run by AstraZeneca. The registered enrollment target is 254 participants, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (303% higher). The trial reports 4 study locations across 3 states.

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The verdict

NCT06908577, a Phase 1 study of Healthy Participants, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
254 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this study is to compare the pharmacokinetic (PK) exposures of a single subcutaneous (SC) dose of tozorakimab administered using AI or APFS in healthy participants.

Conditions Studied

Interventions

  • DRUG Tozorakimab
  • DEVICE Autoinjector (AI) Device
  • DEVICE Accessorised Prefilled Syringe (APFS) Device

Study Locations (4)

Other

  • Research Site - Berlin
  • Research Site - Harrow

California

  • Research Site - Glendale

Maryland

  • Research Site - Baltimore

Trial Details

FieldValue
Enrollment Target 254 participants
Start Date 2025-04-07
Est. Completion 2025-11-25
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT06908577

The ClinicalTrials.gov registry entry for NCT06908577 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 254 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (303% higher). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 3 interventions - of which Tozorakimab is the first listed.

NCT06908577 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Other, California, Maryland.

Frequently Asked Questions

What is clinical trial NCT06908577 about?

NCT06908577 is a clinical study titled "An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab". The purpose of this study is to compare the pharmacokinetic (PK) exposures of a single subcutaneous (SC) dose of tozorakimab administered using AI or APFS in healthy participants.

What is the current status of trial NCT06908577?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 254 participants. The study started on 2025-04-07. Estimated completion is 2025-11-25.

What conditions does trial NCT06908577 study?

This clinical trial studies the following conditions: Healthy Participants.

What interventions are being tested in trial NCT06908577?

The interventions under investigation include: Tozorakimab (DRUG), Autoinjector (AI) Device (DEVICE), Accessorised Prefilled Syringe (APFS) Device (DEVICE).

Who is sponsoring clinical trial NCT06908577?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06908577 being conducted?

This trial has 4 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.