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NCT07226635 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone
A Phase 1 study of Healthy Participants, sponsored by Sparrow Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT07226635: Completed Phase 1 study of Healthy Participants, sponsored by Sparrow Pharmaceuticals.
NCT07226635 is a Phase 1 study of Healthy Participants that has completed, run by Sparrow Pharmaceuticals. The registered enrollment target is 16 participants, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226635, a Phase 1 study of Healthy Participants, has completed, sponsored by Sparrow Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
Drug: 2 single oral doses of midazolam, 2 single oral doses of prednisolone , and clofutriben once daily for 16 days.
Primary Outcome
It will be concluded that there is no relevant interaction of clofutriben on midazolam if the 90% CIs for the Cmax ratios (midazolam + clofutriben)/midazolam alone) are contained within the \[80%, 125%\] interval.
Conditions Studied
Interventions
- DRUG midazolam
- DRUG clofutriben once daily for 16 days
- DRUG 2 single oral doses of prednisolone
Study Locations (1)
Texas
- PPD Austin Research Unit - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-10-03 |
| Est. Completion | 2025-12-16 |
| Phase | Phase 1 |
What the finished NCT07226635 record still lists
NCT07226635 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 3 interventions - of which midazolam is the first listed.
NCT07226635 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07226635 about?
NCT07226635 is a clinical study titled "Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone". Drug: 2 single oral doses of midazolam, 2 single oral doses of prednisolone , and clofutriben once daily for 16 days.
What is the current status of trial NCT07226635?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-10-03. Estimated completion is 2025-12-16.
What conditions does trial NCT07226635 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT07226635?
The interventions under investigation include: midazolam (DRUG), clofutriben once daily for 16 days (DRUG), 2 single oral doses of prednisolone (DRUG).
Who is sponsoring clinical trial NCT07226635?
This trial is sponsored by Sparrow Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07226635 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07226635's enrollment target sits among peer trials
16 97th of 119 higher than 16 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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