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NCT05720494 · ClinicalTrials.gov registry record · Phase 1
A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JZP441 in Healthy Participants
A Phase 1 study of Healthy Participants, sponsored by Jazz Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05720494: Completed Phase 1 study of Healthy Participants, sponsored by Jazz Pharmaceuticals.
NCT05720494 is a Phase 1 study of Healthy Participants that has completed, run by Jazz Pharmaceuticals. The registered enrollment target is 24 participants, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05720494, a Phase 1 study of Healthy Participants, has completed, sponsored by Jazz Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Treatments for narcolepsy and hypersomnolence disorders should have good oral bioavailability and brain penetration properties. JZP441 has demonstrated wake-promoting efficacy and anticataplectic activity in nonclinical studies and may represent a novel approach for these patients.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG JZP441
Study Locations (1)
Utah
- Clinical Site 1 - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2023-01-26 |
| Est. Completion | 2023-09-29 |
| Phase | Phase 1 |
What the finished NCT05720494 record still lists
NCT05720494 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (63% lower).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05720494 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT05720494 about?
NCT05720494 is a clinical study titled "A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JZP441 in Healthy Participants". Treatments for narcolepsy and hypersomnolence disorders should have good oral bioavailability and brain penetration properties. JZP441 has demonstrated wake-promoting efficacy and anticataplectic activity in nonclinical studies and may represent a novel approach for these patients.
What is the current status of trial NCT05720494?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2023-01-26. Estimated completion is 2023-09-29.
What conditions does trial NCT05720494 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT05720494?
The interventions under investigation include: Placebo (DRUG), JZP441 (DRUG).
Who is sponsoring clinical trial NCT05720494?
This trial is sponsored by Jazz Pharmaceuticals, which has 128 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05720494 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05720494's enrollment target sits among peer trials
24 80th of 119 higher than 30 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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