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NCT06835465 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants
A Phase 1 study of Healthy Participants, sponsored by Genentech.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT06835465 is a Phase 1 study of Healthy Participants that has completed, run by Genentech. The registered enrollment target is 18 participants, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06835465, a Phase 1 study of Healthy Participants, has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a phase 1, open-label, two-period, fixed sequence drug-drug interaction study to evaluate the impact of multiple doses of rifampin on the pharmacokinetics (PK) and safety of divarasib in healthy participants.
Conditions Studied
Interventions
- DRUG Divarasib
- DRUG Rifampin
Study Locations (1)
Texas
- Fortrea Dallas CRU - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2025-02-21 |
| Est. Completion | 2025-05-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06835465
The ClinicalTrials.gov registry entry for NCT06835465 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (72% lower). The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Divarasib is the first listed.
NCT06835465 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06835465 about?
NCT06835465 is a clinical study titled "A Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants". This is a phase 1, open-label, two-period, fixed sequence drug-drug interaction study to evaluate the impact of multiple doses of rifampin on the pharmacokinetics (PK) and safety of divarasib in healthy participants.
What is the current status of trial NCT06835465?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2025-02-21. Estimated completion is 2025-05-06.
What conditions does trial NCT06835465 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT06835465?
The interventions under investigation include: Divarasib (DRUG), Rifampin (DRUG).
Who is sponsoring clinical trial NCT06835465?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06835465 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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