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NCT05901714 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
A Phase 1 study of Healthy Participants, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 65
- Enrollment target
- 1
- Study location
NCT05901714: Completed Phase 1 study of Healthy Participants, sponsored by Bristol-Myers Squibb.
NCT05901714 is a Phase 1 study of Healthy Participants that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 65 participants, roughly in line with the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05901714, a Phase 1 study of Healthy Participants, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 65 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will consist of 2 parts. The study will evaluate whether administration of phenytoin impacts the single-dose drug levels of afimetoran and BMT-271199 (Part 1) and will evaluate whether multiple administrations of afimetoran impact the drug levels of midazolam and 1-hydroxymidazolam (Part 2).
Primary Outcome
Parts 1 and 2
Conditions Studied
Interventions
- DRUG Midazolam
- DRUG Afimetoran
- DRUG Phenytoin
Study Locations (1)
Florida
- Local Institution - 0001 - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2023-06-14 |
| Est. Completion | 2024-04-11 |
| Phase | Phase 1 |
What the finished NCT05901714 record still lists
NCT05901714 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, roughly in line with the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target.
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 3 interventions - of which Midazolam is the first listed.
NCT05901714 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05901714 about?
NCT05901714 is a clinical study titled "A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam". This study will consist of 2 parts. The study will evaluate whether administration of phenytoin impacts the single-dose drug levels of afimetoran and BMT-271199 (Part 1) and will evaluate whether multiple administrations of afimetoran impact the drug levels of midazolam and 1-hydroxymidazolam (Part ...
What is the current status of trial NCT05901714?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 65 participants. The study started on 2023-06-14. Estimated completion is 2024-04-11.
What conditions does trial NCT05901714 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT05901714?
The interventions under investigation include: Midazolam (DRUG), Afimetoran (DRUG), Phenytoin (DRUG).
Who is sponsoring clinical trial NCT05901714?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05901714 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05901714's enrollment target sits among peer trials
65 36th of 119 higher than 84 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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