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NCT07487740 · ClinicalTrials.gov registry record · Phase 1

A Food Effect Study to Evaluate the Relative Bioavailability of Nalbuphine Extended-Release Tablets (NAL ER) in Healthy Participants

A Phase 1 study of Healthy Participants, sponsored by Trevi Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
60
Enrollment target
1
Study location

NCT07487740 is a Phase 1 study of Healthy Participants that is actively recruiting participants, run by Trevi Therapeutics. The registered enrollment target is 60 participants, roughly in line with the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT07487740, a Phase 1 study of Healthy Participants, is actively recruiting participants, sponsored by Trevi Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The primary purpose of this study is to evaluate the effect of a high-fat, high-calorie meal on the relative bioavailability of NAL ER following single oral doses.

Conditions Studied

Interventions

  • DRUG NAL ER

Study Locations (1)

Florida

  • Clinical Pharmacology of Miami, LLC. - Miami

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2026-02-27
Est. Completion 2026-04
Phase Phase 1

Sponsor

Trevi Therapeutics

9 total trials

What the Registry Record Tells You About NCT07487740

The ClinicalTrials.gov registry entry for NCT07487740 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target. The listed sponsor is Trevi Therapeutics, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 1 intervention - of which NAL ER is the first listed.

NCT07487740 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT07487740 about?

NCT07487740 is a clinical study titled "A Food Effect Study to Evaluate the Relative Bioavailability of Nalbuphine Extended-Release Tablets (NAL ER) in Healthy Participants". The primary purpose of this study is to evaluate the effect of a high-fat, high-calorie meal on the relative bioavailability of NAL ER following single oral doses.

What is the current status of trial NCT07487740?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2026-02-27. Estimated completion is 2026-04.

What conditions does trial NCT07487740 study?

This clinical trial studies the following conditions: Healthy Participants.

What interventions are being tested in trial NCT07487740?

The interventions under investigation include: NAL ER (DRUG).

Who is sponsoring clinical trial NCT07487740?

This trial is sponsored by Trevi Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07487740 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.