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NCT06132841 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

A Phase 1 study of Healthy Participants, sponsored by AstraZeneca.

Active
Registry status
Phase 1
Development phase
104
Enrollment target
3
Study locations

NCT06132841: Active Phase 1 study of Healthy Participants, sponsored by AstraZeneca.

NCT06132841 is a Phase 1 study of Healthy Participants that is active but no longer recruiting, run by AstraZeneca. The registered enrollment target is 104 participants, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (60% higher). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06132841, a Phase 1 study of Healthy Participants, is active but no longer recruiting, sponsored by AstraZeneca.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
104 participants
Enrollment target
3
Study locations

Study Summary

A study in healthy male and female participants of non-childbearing and childbearing potential who have overweight or obesity

Primary Outcome

The safety and tolerability of repeated subcutaneous (SC) doses of AZD6234 compared to placebo will be assessed.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG AZD6234

Study Locations (3)

California

  • Research Site - Glendale

Maryland

  • Research Site - Brooklyn

Other

  • Research Site - Osaka

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2023-11-13
Est. Completion 2026-03-23
Phase Phase 1
AstraZeneca

1,285 total trials

What the registry record for NCT06132841 still lists

NCT06132841 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (60% higher).

The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06132841 reports a single indexed study location in California, Maryland, Other.

Frequently Asked Questions

What is clinical trial NCT06132841 about?

NCT06132841 is a clinical study titled "A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese". A study in healthy male and female participants of non-childbearing and childbearing potential who have overweight or obesity

What is the current status of trial NCT06132841?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 104 participants. The study started on 2023-11-13. Estimated completion is 2026-03-23.

What conditions does trial NCT06132841 study?

This clinical trial studies the following conditions: Healthy Participants.

What interventions are being tested in trial NCT06132841?

The interventions under investigation include: Placebo (DRUG), AZD6234 (DRUG).

Who is sponsoring clinical trial NCT06132841?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06132841 being conducted?

This trial has 3 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Participants

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06132841's enrollment target sits among peer trials

104 19th of 119 higher than 101 of 119 other Healthy Participants trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06132841, the US trial registry maintained by the National Library of Medicine. NCT06132841 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.