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NCT07290283 · ClinicalTrials.gov registry record · Phase 1

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants

A Phase 1 study of Healthy Participants, sponsored by AstraZeneca.

Recruiting
Registry status
Phase 1
Development phase
176
Enrollment target
2
Study locations

NCT07290283 is a Phase 1 study of Healthy Participants that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 176 participants, above the 64-participant average among 119 other Healthy Participants trials with a reported enrollment target (175% higher). The trial reports 2 study locations across 2 states.

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The verdict

NCT07290283, a Phase 1 study of Healthy Participants, is actively recruiting participants, sponsored by AstraZeneca.

RECRUITING
Registry status
Phase 1
Development phase
176 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administration to healthy participants, including participants of Japanese and Chinese descent.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG AZD3974

Study Locations (2)

California

  • Research Site - Glendale

Maryland

  • Research Site - Baltimore

Trial Details

FieldValue
Enrollment Target 176 participants
Start Date 2025-12-10
Est. Completion 2026-10-21
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT07290283

The ClinicalTrials.gov registry entry for NCT07290283 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 176 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 64-participant average among 119 other Healthy Participants trials with a reported enrollment target (175% higher). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07290283 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Maryland.

Frequently Asked Questions

What is clinical trial NCT07290283 about?

NCT07290283 is a clinical study titled "A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants". The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administration to healthy participants, including participants of Japanese and Chinese descent.

What is the current status of trial NCT07290283?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 176 participants. The study started on 2025-12-10. Estimated completion is 2026-10-21.

What conditions does trial NCT07290283 study?

This clinical trial studies the following conditions: Healthy Participants.

What interventions are being tested in trial NCT07290283?

The interventions under investigation include: Placebo (OTHER), AZD3974 (DRUG).

Who is sponsoring clinical trial NCT07290283?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07290283 being conducted?

This trial has 2 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.