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NCT07122986 · ClinicalTrials.gov registry record · Phase 1

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

A Phase 1 study of Healthy Participants, sponsored by Pfizer.

Recruiting
Registry status
Phase 1
Development phase
310
Enrollment target
11
Study locations

NCT07122986 is a Phase 1 study of Healthy Participants that is actively recruiting participants, run by Pfizer. The registered enrollment target is 310 participants, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (392% higher). The trial reports 11 study locations across 5 states.

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The verdict

NCT07122986, a Phase 1 study of Healthy Participants, is actively recruiting participants, sponsored by Pfizer.

RECRUITING
Registry status
Phase 1
Development phase
310 participants
Enrollment target
11
Study locations

Study Summary

This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.

Conditions Studied

Interventions

  • DRUG E coli vaccine 1 Dose A
  • DRUG E coli vaccine 1 Dose B
  • DRUG E coli vaccine 2
  • DRUG E coli vaccine 3
  • DRUG E coli Vaccine 4 Dose A

Study Locations (11)

California

  • Anaheim Clinical Trials, LLC - Anaheim
  • Orange County Research Center - Lake Forest
  • Diablo Clinical Research, Inc. - Walnut Creek

Tennessee

  • Alliance for Multispecialty Research, LLC - Knoxville
  • Alliance for Multispecialty Research, LLC - Knoxville
  • University Eye Specialists, P.C. (Ophthalmologist) - Maryville

Florida

  • Miami Eye Institute - Hollywood
  • Research Centers of America - Hollywood

Ohio

  • CTI Clinical Research Center - Cincinnati
  • Senders Pediatrics - South Euclid

New York

  • NYU Langone Health - New York

Trial Details

FieldValue
Enrollment Target 310 participants
Start Date 2025-08-11
Est. Completion 2028-05-26
Phase Phase 1

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT07122986

The ClinicalTrials.gov registry entry for NCT07122986 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 310 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (392% higher). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 5 interventions - of which E coli vaccine 1 Dose A is the first listed.

NCT07122986 reports 11 study locations spanning 5 distinct geographic areas - top geographies include California, Tennessee, Florida.

Frequently Asked Questions

What is clinical trial NCT07122986 about?

NCT07122986 is a clinical study titled "A Study to Learn About a Vaccine Against E Coli in Healthy Adults". This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.

What is the current status of trial NCT07122986?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 310 participants. The study started on 2025-08-11. Estimated completion is 2028-05-26.

What conditions does trial NCT07122986 study?

This clinical trial studies the following conditions: Healthy Participants.

What interventions are being tested in trial NCT07122986?

The interventions under investigation include: E coli vaccine 1 Dose A (DRUG), E coli vaccine 1 Dose B (DRUG), E coli vaccine 2 (DRUG), E coli vaccine 3 (DRUG), E coli Vaccine 4 Dose A (DRUG).

Who is sponsoring clinical trial NCT07122986?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07122986 being conducted?

This trial has 11 study locations across California, Florida, New York, Ohio, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.