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NCT07122986 · ClinicalTrials.gov registry record · Phase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
A Phase 1 study of Healthy Participants, sponsored by Pfizer.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 310
- Enrollment target
- 11
- Study locations
NCT07122986: Recruiting Phase 1 study of Healthy Participants, sponsored by Pfizer.
NCT07122986 is a Phase 1 study of Healthy Participants that is actively recruiting participants, run by Pfizer. The registered enrollment target is 310 participants, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (392% higher). The trial reports 11 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07122986, a Phase 1 study of Healthy Participants, is actively recruiting participants, sponsored by Pfizer.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 310 participants
- Enrollment target
- 11
- Study locations
Study Summary
This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.
Primary Outcome
Prespecified local reactions (redness, swelling, and pain at the injection site) following each vaccination
Conditions Studied
Interventions
- DRUG E coli vaccine 1 Dose A
- DRUG E coli vaccine 1 Dose B
- DRUG E coli vaccine 2
- DRUG E coli vaccine 3
- DRUG E coli Vaccine 4 Dose A
Study Locations (11)
California
- Anaheim Clinical Trials, LLC - Anaheim
- Orange County Research Center - Lake Forest
- Diablo Clinical Research, Inc. - Walnut Creek
Tennessee
- Alliance for Multispecialty Research, LLC - Knoxville
- Alliance for Multispecialty Research, LLC - Knoxville
- University Eye Specialists, P.C. (Ophthalmologist) - Maryville
Florida
- Miami Eye Institute - Hollywood
- Research Centers of America - Hollywood
Ohio
- CTI Clinical Research Center - Cincinnati
- Senders Pediatrics - South Euclid
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 310 participants |
| Start Date | 2025-08-11 |
| Est. Completion | 2028-05-26 |
| Phase | Phase 1 |
What NCT07122986 shows while recruiting
NCT07122986 is an interventional study that assigns participants to a tested intervention. The registered 310 participants enrollment target is mid-sized for trials with a published cap, above the 63-participant average among 119 other Healthy Participants trials with a reported enrollment target (392% higher).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 5 interventions - of which E coli vaccine 1 Dose A is the first listed.
NCT07122986 lists 11 locations in 5 states (California, Tennessee, Florida).
Frequently Asked Questions
What is clinical trial NCT07122986 about?
NCT07122986 is a clinical study titled "A Study to Learn About a Vaccine Against E Coli in Healthy Adults". This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.
What is the current status of trial NCT07122986?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 310 participants. The study started on 2025-08-11. Estimated completion is 2028-05-26.
What conditions does trial NCT07122986 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT07122986?
The interventions under investigation include: E coli vaccine 1 Dose A (DRUG), E coli vaccine 1 Dose B (DRUG), E coli vaccine 2 (DRUG), E coli vaccine 3 (DRUG), E coli Vaccine 4 Dose A (DRUG).
Who is sponsoring clinical trial NCT07122986?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07122986 being conducted?
This trial has 11 study locations across California, Florida, New York, Ohio, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Participants
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07122986's enrollment target sits among peer trials
310 5th of 119 higher than 115 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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