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NCT07231497 · ClinicalTrials.gov registry record · Phase 3
Cognitive Strategies in Early Psychosis 1
A Phase 3 study of Healthy Participants and Cognition, sponsored by University of Minnesota.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 103
- Enrollment target
- 1
- Study location
NCT07231497: Recruiting Phase 3 study of Healthy Participants and Cognition, sponsored by University of Minnesota.
NCT07231497 is a Phase 3 study of Healthy Participants and Cognition that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 103 participants, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (58% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07231497, a Phase 3 study of Healthy Participants and Cognition, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 103 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do not have psychosis to take a single dose of modafinil and then complete some brain games on the computer that measure decision making. They hope to improve our understanding of psychosis to help people in the future. The main research questions are: Does a single dose of modafinil change how people play the brain games? Does a single dose of modafinil change brain activity? Participants will: Complete an interview and self-report questionnaires. Complete safety screening activities, like a blood draw, a urine drug test, and an alcohol breathalyzer test. Take a single dose of modafinil. Complete brain games while wearing an electroencephalography (EEG) cap, before and after taking the single dose of modafinil. EEG measures electrical activity in the brain.
Primary Outcome
A computerized cognitive assessment measuring processing speed. Z scores range from -5 to 5, with a higher score indicating increased cognitive functioning.
Conditions Studied
Interventions
- DRUG Modafinil
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 103 participants |
| Start Date | 2025-10-31 |
| Est. Completion | 2030-04-30 |
| Phase | Phase 3 |
What NCT07231497 shows while recruiting
NCT07231497 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, above the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (58% higher).
The record links to 2 conditions, with Healthy Participants appearing as the primary indexed condition, and to 1 intervention - of which Modafinil is the first listed.
NCT07231497 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT07231497 about?
NCT07231497 is a clinical study titled "Cognitive Strategies in Early Psychosis 1". The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do not have psychosis to take a single dose of modafinil and then complete some brain games on the computer that measure decision making. They h...
What is the current status of trial NCT07231497?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 103 participants. The study started on 2025-10-31. Estimated completion is 2030-04-30.
What conditions does trial NCT07231497 study?
This clinical trial studies the following conditions: Healthy Participants, Cognition.
What interventions are being tested in trial NCT07231497?
The interventions under investigation include: Modafinil (DRUG).
Who is sponsoring clinical trial NCT07231497?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07231497 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Participants
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07231497's enrollment target sits among peer trials
103 20th of 119 higher than 100 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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