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Glaucoma: full-pipeline trial registry
39 of 94 indexed Glaucoma trials are currently recruiting.
Corpus placement: #143 of 28,707 conditions by registered trial count.
94 US clinical trials · 39 currently recruiting · #143 of 28,707 conditions by registered trial count
Glaucoma: 94 US clinical trials tracked, 39 recruiting.
Glaucoma is the subject of 94 registered US clinical trials on ClinicalTrials.gov, 39 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 8 of these trials.
Enrollment posture brief
Registry condition glaucoma
OPEN 39 | RECR 41% | LATE 16 | EARLY 21 | RANK #143 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Post Traumatic Stress Disorder (42% recruiting · 265 trials)
Glaucoma lists 39 open slots (41% of 94 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Glaucoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Glaucoma recruits in line with its size-band peers.
39 of 94 indexed trials (41.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Glaucoma trials is spread across many organizations.
Stanford University accounts for 8 of 94 trials (8.5%). 56 distinct sponsors appear on at least one study for this condition label.
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Typical Glaucoma enrolment sits around 92 participants.
Median target enrolment is 92 among the 93 trials that report a genuine target (sentinel values excluded). 48 of those (51.6%) plan for fewer than 100 participants.
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Glaucoma research is mostly interventional.
71 interventional and 23 observational studies make up this index (75.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
94 total, page 2 of 2
Examining The Efficacy, Safety And Improved Tolerability Of Travoprost BAK Free Ophthalmic Solution (Travatan-Z) Compared To Prior Prostaglandin Therapy
Alcon Research
NCT00444665
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients
Laboratoires Thea
NCT05397600
Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
Bausch & Lomb Incorporated
NCT03896633
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
Allergan
NCT00652106
Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension
Novartis Pharmaceuticals
NCT00846989
Bimatoprost 0.03% Versus Travoprost 0.004% in Patients Currently on Latanoprost 0.005%
Allergan
NCT00440011
Primary Tube Versus Trabeculectomy Study
University of Miami
NCT00666237
Pigment Dispersion Syndrome With and Without Glaucoma
National Eye Institute (NEI)
NCT00001152
Chart Review of XEN 45 Gel Stent: Long Term Performance and Safety Assessment (XEN LT)
Allergan
NCT03868254
Will Listening to Music Make it Easier to Take a Visual Field Test?
Wills Eye
NCT01027039
A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma
Inotek Pharmaceuticals Corporation
NCT01123785
Macular Ganglion Cell Analysis (GCA) of the Cirrus HD-OCT in Glaucoma
Carl Zeiss Meditec
NCT01272102
Ahmed Glaucoma Valve Surgery With Mitomycin-C
University of California, San Francisco
NCT02805257
A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertension
Allergan
NCT01863953
The eyeGuide: Improving Glaucoma Self-management With a Personalized Behavior Change Program
University of Michigan
NCT03159247
Testing Latest Version of NidekRS3000Adv
Doheny Image Reading Center
NCT03318705
Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy
Lahey Clinic
NCT00695747
Steroid Eyedrop Adherence After Trabeculectomy
Johns Hopkins University
NCT03402802
Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma
Amakem
NCT01693315
Baerveldt 350 vs Ahmed ClearPath 250 for the Treatment of Glaucoma
State University of New York at Buffalo
NCT04542616
AZARGA Transition Study in Taiwan for Patients With Uncontrolled Intraocular Pressure
Alcon Research
NCT01484951
Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma
Dompé Farmaceutici S.p.A
NCT02855450
Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance
Ohio State University
NCT04412096
How Similar Are Changes to the Surface of the Eye When Two Different Glaucoma Eye Drops Are Used?
Wills Eye
NCT00798694
SDOCT-GMPE Software
Duke University
NCT02235454
A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma
Mati Therapeutics
NCT01481051
Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data
Indiana University
NCT01145898
Topcon 3D OCT-1000 Optical Coherence Tomography System
Topcon Medical Systems
NCT00792259
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).
Hoffmann-La Roche
NCT02622334
Effect of Glaucoma Educators on Adherence to Prescribed Therapeutic Regimens in Glaucoma Patients
University of Colorado, Denver
NCT00454922
Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)
Cornerstone Health Care, PA
NCT02167035
Comparing the Effect of the Water Drinking Test on Intraocular Pressure
Wills Eye
NCT02001155
Aqueous Suppressant Versus Aqueous Outflow on Ocular Blood Flow
Indiana University
NCT01308788
Circadian Rhythms of Aqueous Humor Dynamics in Humans
University of Nebraska
NCT00572936
Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects
University of Wisconsin, Madison
NCT01864642
Lucentis Versus Mitomycin C During Glaucoma Surgery
Wills Eye
NCT00626782
The Effects of the Water Drinking Test on Intraocular Pressure
University of California, San Diego
NCT01507584
Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)
Massachusetts Eye and Ear Infirmary
NCT00824824
An App-based Instructional Platform to Improve Eye Drop Recall
University of California, San Francisco
NCT06045390
A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma
NYU Langone Health
NCT03188042
Does Oral Acetaminophen Lower Intraocular Pressure?
Johns Hopkins University
NCT02366065
Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With Glaucoma
Stanford University
NCT04035239
Adult Providing Access to the Visual Environment (PAVE) - Glaucoma Pilot
Vanderbilt University
NCT00338208
Efficacy of Bimatoprost 0.03% in Patients Who Are Low-Responders to Latanoprost
Innovative Medical
NCT00347841
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 10 |
| Phase 3 | 5 |
| Phase 4 | 11 |
Top Sponsors
Named interventions
Most-linked intervention names on Glaucoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Glaucoma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Glaucoma page
94 registered trials, 39 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 39 Glaucoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Stanford University sponsors the most Glaucoma trials on record, review their full trial history before evaluating a specific study. See Stanford University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Glaucoma condition card totals 94 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.