Glaukos Corporation
Glaukos Corporation sponsors 33 registered US clinical trials on ClinicalTrials.gov, 11 of them currently recruiting, and 17 completed. 14 of these trials are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glaucoma Open-Angle, with 4 trials.
Trial Pipeline
33 total, page 1 of 1
Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus
NCT07629557
Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
NCT07495852
Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus
NCT07400952
Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg
NCT07400926
Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
NCT07400965
Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
NCT07075718
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
NCT06848946
Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone
NCT06066645
Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma
NCT06057051
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
NCT05966493
Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus
NCT05314738
iStent Inject New Enrollment Post-Approval Study
NCT04624698
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease
NCT05119920
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia
NCT05124275
Study of Exchange of Travoprost Intraocular Implant
NCT04615403
NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Injuries
NCT04081103
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
NCT03868124
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%
NCT03519386
Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus
NCT03442751
Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution
NCT02754596
Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty
NCT02327312
Safety and Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus
NCT01972854
Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket Registry
NCT01841437
Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism
NCT01893359
Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort
NCT01836042
Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus
NCT01344187
Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus
NCT01643226
Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery
NCT01461291
Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery
NCT01461278
GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma
NCT01052558
Corneal Collagen Cross-Linking for Ectasia (CXL)
NCT00674661
Corneal Collagen Cross-linking for Progressive Keratoconus
NCT00647699
A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma
NCT00323284
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 9 |
| Phase 3 | 12 |
| Phase 4 | 2 |
What the Pipeline for Glaukos Corporation Shows
According to the ClinicalTrials.gov registry, Glaukos Corporation is linked to 33 US clinical trials across every stage of research activity. Of those, 11 studies are currently recruiting, about 33% of the sponsor's indexed portfolio, and 17 are already marked complete, representing roughly 52% of the total.
The phase mix for Glaukos Corporation reports 14 late-stage studies (Phase 3 and Phase 4 combined) and 11 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Glaukos Corporation is Glaucoma Open-Angle with 4 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.