Glaukos Corporation

33 total trials 11 currently recruiting 17 completed

Glaukos Corporation sponsors 33 registered US clinical trials on ClinicalTrials.gov, 11 of them currently recruiting, and 17 completed. 14 of these trials are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glaucoma Open-Angle, with 4 trials.

Trial Pipeline

33 total, page 1 of 1

RECRUITING Phase 4

Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus

NCT07629557

RECRUITING Phase 3

Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

NCT07495852

RECRUITING Phase 2

Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus

NCT07400952

RECRUITING

Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

NCT07400926

RECRUITING Phase 2

Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis

NCT07400965

RECRUITING Phase 2

Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

NCT07075718

RECRUITING Phase 4

Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone

NCT06848946

RECRUITING Phase 3

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

NCT06066645

RECRUITING NA

Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma

NCT06057051

RECRUITING Phase 2

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

NCT05966493

RECRUITING Phase 1

Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus

NCT05314738

ACTIVE NOT RECRUITING NA

iStent Inject New Enrollment Post-Approval Study

NCT04624698

COMPLETED Phase 2

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease

NCT05119920

COMPLETED Phase 2

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

NCT05124275

COMPLETED Phase 2

Study of Exchange of Travoprost Intraocular Implant

NCT04615403

TERMINATED Phase 2

NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Injuries

NCT04081103

COMPLETED Phase 3

Clinical Study Comparing Two Models of a Travoprost Intraocular Implant

NCT03868124

COMPLETED Phase 3

Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%

NCT03519386

COMPLETED Phase 3

Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus

NCT03442751

COMPLETED Phase 2

Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution

NCT02754596

TERMINATED NA

Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty

NCT02327312

TERMINATED Phase 3

Safety and Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus

NCT01972854

COMPLETED

Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket Registry

NCT01841437

TERMINATED Phase 1

Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism

NCT01893359

COMPLETED

Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort

NCT01836042

COMPLETED Phase 3

Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus

NCT01344187

COMPLETED Phase 3

Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus

NCT01643226

COMPLETED NA

Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery

NCT01461291

COMPLETED NA

Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery

NCT01461278

COMPLETED Phase 3

GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma

NCT01052558

COMPLETED Phase 3

Corneal Collagen Cross-Linking for Ectasia (CXL)

NCT00674661

COMPLETED Phase 3

Corneal Collagen Cross-linking for Progressive Keratoconus

NCT00647699

COMPLETED Phase 3

A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma

NCT00323284

What the Pipeline for Glaukos Corporation Shows

According to the ClinicalTrials.gov registry, Glaukos Corporation is linked to 33 US clinical trials across every stage of research activity. Of those, 11 studies are currently recruiting, about 33% of the sponsor's indexed portfolio, and 17 are already marked complete, representing roughly 52% of the total.

The phase mix for Glaukos Corporation reports 14 late-stage studies (Phase 3 and Phase 4 combined) and 11 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Glaukos Corporation is Glaucoma Open-Angle with 4 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.