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NCT06993597 · ClinicalTrials.gov registry record

Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

A clinical trial of Glaucoma, sponsored by University of Maryland, Baltimore.

Recruiting
Registry status
60
Enrollment target
1
Study location

NCT06993597 is a study of Glaucoma that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 60 participants, below the 910-participant average among 92 other Glaucoma trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06993597, a study of Glaucoma, is actively recruiting participants, sponsored by University of Maryland, Baltimore.

RECRUITING
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

This pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy controls, and to assess changes in corneal biomechanics following intraocular pressure (IOP)-lowering treatment. The goal is to determine whether Brillouin-derived biomechanical measurements can serve as biomarkers for glaucoma risk and progression.

Conditions Studied

Glaucoma

Interventions

  • DRUG Prostaglandin Analogue -Containing IOP-Lowering Therapy
  • DRUG Beta Blocker
  • DEVICE Brillouin Microscopy

Study Locations (1)

Maryland

  • University of Maryland School of Medicine - Baltimore

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-09-01
Est. Completion 2026-06

Sponsor

University of Maryland, Baltimore

560 total trials

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What the Registry Record Tells You About NCT06993597

The ClinicalTrials.gov registry entry for NCT06993597 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 910-participant average among 92 other Glaucoma trials with a reported enrollment target (93% lower). The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glaucoma appearing as the primary indexed condition, and to 3 interventions - of which Prostaglandin Analogue -Containing IOP-Lowering Therapy is the first listed.

NCT06993597 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT06993597 about?

NCT06993597 is a clinical study titled "Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy". This pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy controls, and to asses...

What is the current status of trial NCT06993597?

This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2025-09-01. Estimated completion is 2026-06.

What conditions does trial NCT06993597 study?

This clinical trial studies the following conditions: Glaucoma.

What interventions are being tested in trial NCT06993597?

The interventions under investigation include: Prostaglandin Analogue -Containing IOP-Lowering Therapy (DRUG), Beta Blocker (DRUG), Brillouin Microscopy (DEVICE).

Who is sponsoring clinical trial NCT06993597?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06993597 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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