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Diabetes Mellitus: full-pipeline trial registry
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
Corpus placement: #44 of 28,707 conditions by registered trial count.
210 US clinical trials · 49 currently recruiting · #44 of 28,707 conditions by registered trial count
Diabetes Mellitus: 210 US clinical trials tracked, 49 recruiting.
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus
OPEN 49 | RECR 23% | LATE 26 | EARLY 32 | RANK #44 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Alzheimers Disease (23% recruiting · 150 trials)
Diabetes Mellitus lists 49 open slots (23% of 210 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetes Mellitus is recruiting below its size-band peers.
49 of 210 indexed trials (23.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetes Mellitus trials is spread across many organizations.
Takeda accounts for 8 of 210 trials (3.8%). 123 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetes Mellitus enrolment sits around 136 participants.
Median target enrolment is 136 among the 209 trials that report a genuine target (sentinel values excluded). 86 of those (41.1%) plan for fewer than 100 participants.
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Diabetes Mellitus research is mostly interventional.
175 interventional and 35 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
210 total, page 4 of 5
Community Paramedicine Program to Improve Diabetes Care Quality, Equity, and Outcomes
Mayo Clinic
NCT04385758
A Clinical Study of the C8 MediSensors Optical Glucose Monitor™
C8 MediSensors
NCT01726114
A Quality Improvement Process to Support Delivery of Cardiovascular Care in Community Mental Health Organizations
Johns Hopkins University
NCT04696653
FreeStyle Libre Continuous Glucose Monitoring System Accuracy Study
Abbott Diabetes Care
NCT04464772
Assessing Non-adjunctive CGM Safety at Home and in New Markets
DexCom
NCT04585139
Single-Dose And Multiple-Dose Safety And Tolerability Study Of PF-04856883 In Type 2 Diabetic Adult Females
Pfizer
NCT01301456
Investigations of the Optimum Serum Bicarbonate Level in Renal Disease.
VA Office of Research and Development
NCT01574157
Safety, Tolerability, Pharmacokinetics,Pharmacodynamics Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
NCT01452451
Prediction of CK-MB Release During Otherwise Successful Stenting Procedure
Icahn School of Medicine at Mount Sinai
NCT00489242
Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19
University of Michigan
NCT05200819
Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea
Mike O'Callaghan Military Hospital
NCT01447251
A Mobile Phone-based Program for Adults With Prediabetes
University of Michigan
NCT03025607
Adapting and Assessing the Feasibility of a Diabetes Self-management Telehealth Intervention
University of Utah
NCT04600622
Comorbidities And Reducing inEquitieS
Medstar Health Research Institute
NCT04836221
Mobile Insulin Titration Intervention
NYU Langone Health
NCT01879579
Evaluation of a Patient Portal Intervention to Address Diabetes Care Gaps
Vanderbilt University Medical Center
NCT04728620
Financial Incentives Telephone Education and Skills Trial in African Americans With Diabetes (FITEST)
State University of New York at Buffalo
NCT02722499
Hippocampal Metabolism and Function in Patients With Type 1 Diabetes
University of Minnesota
NCT01852968
Diabetes Risk Education and Communication Trial
Northwestern University
NCT03283657
Effectiveness and Safety Study of the Dexcom G4 Platinum With Modified Algorithm
DexCom
NCT02087995
A New Glucose Meter With Alternative Site Testing
Ascensia Diabetes Care
NCT00797212
Effects of Use of a Connected Pillbox On Medication Adherence
University of Pennsylvania
NCT02593032
Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes
Geisinger Clinic
NCT03015480
Green Digital Diabetes Waste Project
Florida State University
NCT06071325
Chronic Care Management/Patient Relationship Management Proof of Concept
Denver Health and Hospital Authority
NCT01182480
Diabetic Foot Ulcer (DFU) Rapid Pathogen Identification
University of Michigan
NCT06569238
Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet
Washington University School of Medicine
NCT00763087
Dysvascular Amputation Self-Management of Health
University of Colorado, Denver
NCT04083456
Post-operative Complications and Graft Survival With Conventional Versus Continuous Glucose Monitoring in Patients With Diabetes Mellitus Undergoing Renal Transplantation
Northwell Health
NCT04742023
First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes
Goldfinch Bio
NCT04880291
Managing Diabetes Mindfully Study
HealthPartners Institute
NCT01796834
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients
Baylor College of Medicine
NCT01810952
Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells
Emory University
NCT00166036
A Mind-Body Intervention for Diabetes Management: A Pilot Study
Dartmouth-Hitchcock Medical Center
NCT04944264
Improving Medical Training for the Care of Chronic Conditions
VA Office of Research and Development
NCT00676208
Observational Study to Evaluate the Effectiveness and Safety of the Dexcom G4 Continuous Glucose Monitoring System in Pediatrics
DexCom
NCT02363907
Effect of LY333531 on Vascular and Neural Functions
Chromaderm
NCT00482976
Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00046267
Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)
AstraZeneca
NCT01192139
A Continuous Glucose Monitor Based Insulin Bolus Calculator (CGM-IBC) Study B
Welldoc
NCT05343065
Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents
Eli Lilly and Company
NCT02402933
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes
University of Colorado, Denver
NCT03620773
A Study Comparing the Pharmacodynamic Properties of Insulin VIAJECT™, Regular Human Insulin, and Insulin Lispro
Biodel
NCT01000922
Diabetic Ketoacidosis and Its Impact on the Brain
Stanford University
NCT01753934
A Study of Rapid-Acting Mealtime Insulin in Children and Adolescents With Newly Diagnosed Type 1 Diabetes Mellitus
Emory University
NCT04157738
Automated Insulin Delivery for INpatients With DysGlycemia (AIDING) Feasibility
Emory University
NCT04714216
Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease
University of Washington
NCT00552409
A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome
Washington University School of Medicine
NCT02829268
Effects of URI on Diabetic Subjects Utilizing Technosphere Insulin After a Meal Challenge
Mannkind Corporation
NCT00642681
Advancing the Standard of Care for Pin Site Care
Duke University
NCT01965665
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus page
210 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 49 Diabetes Mellitus trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Takeda sponsors the most Diabetes Mellitus trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus condition card totals 210 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.