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Diabetes Mellitus clinical trials
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
210 US clinical trials · 49 currently recruiting
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
The research picture
Diabetes Mellitus has 210 registered US clinical trials, 49 of them open to new participants right now, about 23% of the total.
- 49
- recruiting participants now
- 23%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Takeda
Active & Recent Trials
210 total, page 3 of 5
Potential Risk Factors for Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001368
Unmet Social Needs Study
VA Office of Research and Development
NCT04977583
Improving Medication Adherence in the Alabama Black Belt
Weill Medical College of Cornell University
NCT02274844
Can Tailored Patient Letters Improve The Quality Of Diabetic Patient Care?
Scranton-Temple Residency Program
NCT00984841
Effect of Case-Management Using Home Monitoring on Diabetes and Blood Pressure Outcomes
Minneapolis Veterans Affairs Medical Center
NCT00935441
Treatment of Peripheral Neuropathy in Patients With Diabetes
Eli Lilly and Company
NCT00044421
Efficacy and Safety Study of Alogliptin and Insulin in the Treatment of Type 2 Diabetes.
Takeda
NCT00286429
Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus
Takeda
NCT00760344
Initiate and Maintain Physical Activity in Clinics: The IMPACT Diabetes Study
Stanford University
NCT02061579
Periprocedural Glycemic Control in Patients Undergoing Coronary Angiography
NYU Langone Health
NCT01419652
Hawaii Patient Reward And Incentives to Support Empowerment
University of Hawaii
NCT02123251
Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.
Takeda
NCT00672919
MY PALS: A Community-Based Physical Activity Support Program for Older Adults
University of Washington
NCT00132288
Effectiveness of Home-Based Health Messaging for Patients With Hypertension and Diabetes
US Department of Veterans Affairs
NCT00119054
A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
National Center for Research Resources (NCRR)
NCT00015626
Improving Aspirin Use in Diabetes: A Cluster Randomized Trial
Northwestern University
NCT00262977
Safety and Efficacy of Inhaled Insulin in Patients With Diabetes and Asthma or COPD
Eli Lilly and Company
NCT00157339
Health Coach Program to Improve Chronic Disease Outcomes Following an Emergency Department Visit
Alameda County Medical Center
NCT02386540
POGO® Automatic Blood Glucose Monitoring System Clinical Study
Intuity Medical
NCT02333864
Post Approval Study of the Eversense® Continuous Glucose Monitoring
Senseonics
NCT03908125
Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women
National Heart, Lung, and Blood Institute (NHLBI)
NCT00666172
Proactive Diabetes Case Management
US Department of Veterans Affairs
NCT00013208
Veterans Walk for Health Study
US Department of Veterans Affairs
NCT00123435
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
Johns Hopkins University
NCT05574699
Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents
Sanofi
NCT00046501
Pharmacist-led Group Medical Visits to Help With Diabetes Management
VA Office of Research and Development
NCT00554671
Health Promoters and Pharmacists in Diabetes Team Management
University of Illinois at Chicago
NCT01498159
Comprehension of Discharge Instructions for Diabetes Therapy and Hospital Readmission
University of Pittsburgh
NCT03279627
AMG 151 Amgen Protocol Number 20100761
Amgen
NCT01464437
The Impact of Diabetes on REvascularization
Vanderbilt University Medical Center
NCT03085524
CONtrolling Disease Using Inexpensive IT - Hypertension in Diabetes
University of Massachusetts, Worcester
NCT01416766
Community Diabetes Education Program Evaluation "Code Evaluation"
The University of Texas Health Science Center, Houston
NCT00151190
Self Monitoring of Blood Glucose With Finger Tip vs. Alternate Site Sampling: Effect on Long Term Glycemic Control
Boston Medical Center
NCT00207207
Accuracy and Precision of the True Vie I3 Continuous Glucose Monitoring System: an Open Label, Multi-Center Trial
Sinocare
NCT05806554
Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk
Icahn School of Medicine at Mount Sinai
NCT03036254
Internet-based Diabetes Education and Case Management
US Department of Veterans Affairs
NCT00105898
Impaired Wound Healing in Diabetic Foot Ulceration
Beth Israel Deaconess Medical Center
NCT00739323
Conexion: A Localized Information Resource on Diabetes and Depression for a Low-income Hispanic Community
Columbia University
NCT03984929
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema
Oxurion
NCT04527107
Mindful Stress Reduction in Diabetes Self-management Education for Veterans
VA Office of Research and Development
NCT02928952
Day and Night Closed-loop in Young People With Type 1 Diabetes
Jaeb Center for Health Research
NCT02925299
Interprofessional Training to Improve Diabetes Care: The ReSPECT Trial
US Department of Veterans Affairs
NCT00854594
Family PALS (PArtners in Lifestyle Support)
University of North Carolina, Chapel Hill
NCT01324011
Diabetes Therapy to Improve BMI and Lung Function in CF
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00072904
Evaluation of a New Blood Glucose Meter System With Capillary and Venous Blood
Ascensia Diabetes Care
NCT00797563
Comparison of Glycemic Control With Smartphone Application
Icahn School of Medicine at Mount Sinai
NCT05592860
Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes Mellitus
Mayo Clinic
NCT00217061
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
T2D Pilot Study for Patients With Uncontrolled Type 2 Diabetes
Duke University
NCT06988540
QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events
Yale University
NCT04514523
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetes Mellitus Trial Landscape
210 indexed Diabetes Mellitus studies · 49 recruiting (23%).
Phase mix: 26 late (III/IV) vs 32 early (I/II).
Top sponsor: Takeda (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetes Mellitus?
PlainTrial tracks 210 US clinical trials for Diabetes Mellitus, of which 49 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetes Mellitus?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.