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ClinicalTrials.gov 49 recruiting now full pipeline #44 of 28,707 conditions

Diabetes Mellitus: full-pipeline trial registry

49 of 210 indexed Diabetes Mellitus trials are currently recruiting.

Corpus placement: #44 of 28,707 conditions by registered trial count.

210 US clinical trials · 49 currently recruiting · #44 of 28,707 conditions by registered trial count

Diabetes Mellitus: 210 US clinical trials tracked, 49 recruiting.

Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.

Enrollment posture brief

Registry condition diabetes-mellitus

OPEN 49 | RECR 23% | LATE 26 | EARLY 32 | RANK #44 | SPON 8

Nearest open-share peer: Alzheimers Disease (23% recruiting · 150 trials)

Spinal Cord Injuries53.2%Mild Cognitive Impairment48.5%Sickle Cell Disease44.4%Atrial Fibrillation29.4%Diabetes Mellitus (this)23%
Open-enrollment share among volume-matched conditions near Diabetes Mellitus

Diabetes Mellitus lists 49 open slots (23% of 210 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diabetes Mellitus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diabetes Mellitus is recruiting below its size-band peers.

    49 of 210 indexed trials (23.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Diabetes Mellitus trials is spread across many organizations.

    Takeda accounts for 8 of 210 trials (3.8%). 123 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diabetes Mellitus enrolment sits around 136 participants.

    Median target enrolment is 136 among the 209 trials that report a genuine target (sentinel values excluded). 86 of those (41.1%) plan for fewer than 100 participants.

  4. Diabetes Mellitus research is mostly interventional.

    175 interventional and 35 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 219Phase 318Phase 48

Open and recent trials

210 total, page 3 of 5

COMPLETED Phase 1 500 participants

Potential Risk Factors for Stroke

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001368

COMPLETED NA 479 participants

Unmet Social Needs Study

VA Office of Research and Development

NCT04977583

COMPLETED NA 473 participants

Improving Medication Adherence in the Alabama Black Belt

Weill Medical College of Cornell University

NCT02274844

COMPLETED NA 467 participants

Can Tailored Patient Letters Improve The Quality Of Diabetic Patient Care?

Scranton-Temple Residency Program

NCT00984841

COMPLETED NA 460 participants

Effect of Case-Management Using Home Monitoring on Diabetes and Blood Pressure Outcomes

Minneapolis Veterans Affairs Medical Center

NCT00935441

COMPLETED Phase 3 400 participants

Treatment of Peripheral Neuropathy in Patients With Diabetes

Eli Lilly and Company

NCT00044421

COMPLETED Phase 3 390 participants

Efficacy and Safety Study of Alogliptin and Insulin in the Treatment of Type 2 Diabetes.

Takeda

NCT00286429

COMPLETED Phase 2 386 participants

Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus

Takeda

NCT00760344

COMPLETED NA 354 participants

Initiate and Maintain Physical Activity in Clinics: The IMPACT Diabetes Study

Stanford University

NCT02061579

COMPLETED Phase 4 351 participants

Periprocedural Glycemic Control in Patients Undergoing Coronary Angiography

NYU Langone Health

NCT01419652

COMPLETED NA 320 participants

Hawaii Patient Reward And Incentives to Support Empowerment

University of Hawaii

NCT02123251

COMPLETED Phase 4 305 participants

Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.

Takeda

NCT00672919

COMPLETED NA 305 participants

MY PALS: A Community-Based Physical Activity Support Program for Older Adults

University of Washington

NCT00132288

COMPLETED NA 302 participants

Effectiveness of Home-Based Health Messaging for Patients With Hypertension and Diabetes

US Department of Veterans Affairs

NCT00119054

COMPLETED Phase 2 300 participants

A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)

National Center for Research Resources (NCRR)

NCT00015626

COMPLETED NA 300 participants

Improving Aspirin Use in Diabetes: A Cluster Randomized Trial

Northwestern University

NCT00262977

COMPLETED Phase 3 299 participants

Safety and Efficacy of Inhaled Insulin in Patients With Diabetes and Asthma or COPD

Eli Lilly and Company

NCT00157339

COMPLETED NA 295 participants

Health Coach Program to Improve Chronic Disease Outcomes Following an Emergency Department Visit

Alameda County Medical Center

NCT02386540

COMPLETED 287 participants

POGO® Automatic Blood Glucose Monitoring System Clinical Study

Intuity Medical

NCT02333864

COMPLETED NA 273 participants

Post Approval Study of the Eversense® Continuous Glucose Monitoring

Senseonics

NCT03908125

COMPLETED Phase 2 270 participants

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

National Heart, Lung, and Blood Institute (NHLBI)

NCT00666172

COMPLETED NA 260 participants

Proactive Diabetes Case Management

US Department of Veterans Affairs

NCT00013208

COMPLETED NA 254 participants

Veterans Walk for Health Study

US Department of Veterans Affairs

NCT00123435

COMPLETED NA 251 participants

Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral

Johns Hopkins University

NCT05574699

COMPLETED Phase 3 250 participants

Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents

Sanofi

NCT00046501

COMPLETED NA 250 participants

Pharmacist-led Group Medical Visits to Help With Diabetes Management

VA Office of Research and Development

NCT00554671

COMPLETED NA 244 participants

Health Promoters and Pharmacists in Diabetes Team Management

University of Illinois at Chicago

NCT01498159

COMPLETED 240 participants

Comprehension of Discharge Instructions for Diabetes Therapy and Hospital Readmission

University of Pittsburgh

NCT03279627

COMPLETED Phase 2 236 participants

AMG 151 Amgen Protocol Number 20100761

Amgen

NCT01464437

COMPLETED 215 participants

The Impact of Diabetes on REvascularization

Vanderbilt University Medical Center

NCT03085524

COMPLETED NA 196 participants

CONtrolling Disease Using Inexpensive IT - Hypertension in Diabetes

University of Massachusetts, Worcester

NCT01416766

COMPLETED Phase 3 180 participants

Community Diabetes Education Program Evaluation "Code Evaluation"

The University of Texas Health Science Center, Houston

NCT00151190

COMPLETED Phase 1 174 participants

Self Monitoring of Blood Glucose With Finger Tip vs. Alternate Site Sampling: Effect on Long Term Glycemic Control

Boston Medical Center

NCT00207207

COMPLETED 159 participants

Accuracy and Precision of the True Vie I3 Continuous Glucose Monitoring System: an Open Label, Multi-Center Trial

Sinocare

NCT05806554

COMPLETED NA 155 participants

Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk

Icahn School of Medicine at Mount Sinai

NCT03036254

COMPLETED NA 152 participants

Internet-based Diabetes Education and Case Management

US Department of Veterans Affairs

NCT00105898

COMPLETED 137 participants

Impaired Wound Healing in Diabetic Foot Ulceration

Beth Israel Deaconess Medical Center

NCT00739323

COMPLETED NA 136 participants

Conexion: A Localized Information Resource on Diabetes and Depression for a Low-income Hispanic Community

Columbia University

NCT03984929

COMPLETED Phase 2 135 participants

A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema

Oxurion

NCT04527107

COMPLETED NA 132 participants

Mindful Stress Reduction in Diabetes Self-management Education for Veterans

VA Office of Research and Development

NCT02928952

COMPLETED NA 131 participants

Day and Night Closed-loop in Young People With Type 1 Diabetes

Jaeb Center for Health Research

NCT02925299

COMPLETED NA 117 participants

Interprofessional Training to Improve Diabetes Care: The ReSPECT Trial

US Department of Veterans Affairs

NCT00854594

COMPLETED NA 108 participants

Family PALS (PArtners in Lifestyle Support)

University of North Carolina, Chapel Hill

NCT01324011

COMPLETED Phase 3 108 participants

Diabetes Therapy to Improve BMI and Lung Function in CF

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00072904

COMPLETED NA 102 participants

Evaluation of a New Blood Glucose Meter System With Capillary and Venous Blood

Ascensia Diabetes Care

NCT00797563

COMPLETED NA 100 participants

Comparison of Glycemic Control With Smartphone Application

Icahn School of Medicine at Mount Sinai

NCT05592860

COMPLETED Phase 3 98 participants

Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes Mellitus

Mayo Clinic

NCT00217061

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED NA 92 participants

T2D Pilot Study for Patients With Uncontrolled Type 2 Diabetes

Duke University

NCT06988540

COMPLETED NA 91 participants

QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events

Yale University

NCT04514523

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 19
Phase 3 18
Phase 4 8

Named interventions

Most-linked intervention names on Diabetes Mellitus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
9 trials
Pioglitazone Drug
5 trials
Metformin Drug
5 trials
THR-149 dose level 3 Drug
2 trials
THR-149 dose level 2 Drug
2 trials
THR-149 dose level 1 Drug
2 trials
Apollo Blood Glucose Monitoring System Device
2 trials
Lispro Drug
2 trials

US sites by state

Facility locations filed on Diabetes Mellitus trials. A trial with sites in several states counts in each.

California 46 trials
Florida 30 trials
Arizona 24 trials
Massachusetts 22 trials
Colorado 22 trials
Maryland 21 trials
Pennsylvania 20 trials
New York 20 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diabetes Mellitus page

210 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 49 Diabetes Mellitus trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Takeda sponsors the most Diabetes Mellitus trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus condition card totals 210 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.