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Diabetes Mellitus clinical trials
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
210 US clinical trials · 49 currently recruiting
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
The research picture
Diabetes Mellitus has 210 registered US clinical trials, 49 of them open to new participants right now, about 23% of the total.
- 49
- recruiting participants now
- 23%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Takeda
Active & Recent Trials
210 total, page 5 of 5
Iron Depletion Therapy for Type 2 DM and NAFLD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00230087
A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME)
ThromboGenics
NCT03666923
Multiple Dose Safety Toelrability, Pharmacokinetics and Midazolam Interaction In Healthy Overweight And Obese Subjects
Pfizer
NCT01757756
A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)
ThromboGenics
NCT03511898
Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes
University of New Mexi
NCT00659165
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fraction
University of Texas Southwestern Medical Center
NCT05139472
Cryovagotomy Diabetes Trial
Emory University
NCT04276051
OT-Led Interdisciplinary Diabetes Self-Management Prgm
Arizona State University
NCT03821662
Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses
Washington University School of Medicine
NCT03618628
Aging and Cellular Mechanism for Insulin Action After Exercise Training
US Department of Veterans Affairs
NCT00018239
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Diabetes Mellitus Trial Landscape
210 indexed Diabetes Mellitus studies · 49 recruiting (23%).
Phase mix: 26 late (III/IV) vs 32 early (I/II).
Top sponsor: Takeda (8 trials), 9 others listed. 10 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Diabetes Mellitus?
PlainTrial tracks 210 US clinical trials for Diabetes Mellitus, of which 49 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Diabetes Mellitus?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.