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ClinicalTrials.gov 79 recruiting now official registry

Dementia clinical trials

79 of 202 indexed Dementia trials are currently recruiting.

202 US clinical trials · 79 currently recruiting

Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.

The research picture

Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.

79
recruiting participants now
39%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
8
top sponsor: University of Washington
Phase 110Phase 219Phase 310Phase 43

Active & Recent Trials

202 total, page 4 of 5

COMPLETED NA 154 participants

Efficacy of Early Stage Alzheimer's Support Groups

University of Washington

NCT00391794

COMPLETED Phase 2 150 participants

iCare Stress Management e-Training for Dementia Family Caregivers

Photozig

NCT01378195

COMPLETED NA 135 participants

Tools for Distance Delivery of an Evidence-based AD Family Caregiver Intervention

NYU Langone Health

NCT02347202

COMPLETED Phase 3 125 participants

Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia

Otsuka Pharmaceutical Development & Commercialization

NCT00095719

COMPLETED NA 109 participants

Anticipating Decline and Providing Therapy

Wake Forest University Health Sciences

NCT06182995

COMPLETED 108 participants

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in Frontotemporal Dementia

National Institute of Mental Health (NIMH)

NCT00613119

COMPLETED Phase 3 107 participants

High Intensity Light Therapy in Alzheimer's Disease

National Center for Complementary and Integrative Health (NCCIH)

NCT00065689

COMPLETED Phase 1 99 participants

Encouraging Cognitive Screenings at African American Churches

University of Kansas Medical Center

NCT05037578

COMPLETED Phase 2 95 participants

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

Eli Lilly and Company

NCT04640077

COMPLETED NA 88 participants

Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI

University of Alabama at Birmingham

NCT03734289

COMPLETED Phase 2 88 participants

Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia

VA Office of Research and Development

NCT02350127

COMPLETED NA 86 participants

Community-based Brain Health Program to Address Dementia Risk

Posit Science Corporation

NCT05529706

COMPLETED NA 80 participants

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

Elizabeth K Rhodus

NCT05202223

COMPLETED NA 75 participants

Caregiver Study Dr. Phillips

AdventHealth

NCT03653871

COMPLETED Phase 2 64 participants

A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease

CuraSen Therapeutics

NCT05104463

COMPLETED NA 61 participants

Effect of Treating Sleep Apnea on Cognition in Patients With Dementia

University of California, San Diego

NCT00477828

COMPLETED 60 participants

Families Affected by Dementia: A Survey of Caregivers

University of Miami

NCT02095327

COMPLETED NA 60 participants

Powerful Tools for Caregivers of Dementia Patients

Florida State University

NCT02697721

COMPLETED NA 50 participants

Effects on Dementia Caregivers

University of Central Florida

NCT06473571

COMPLETED NA 45 participants

Training and Coaching to Promote High Performance in Veteran Affairs (VA) Nursing Home Care

US Department of Veterans Affairs

NCT00875706

COMPLETED NA 42 participants

Distance Savvy: Testing Tele-Savvy, a Distance Dementia Family Caregiver Education Program

Emory University

NCT02300584

COMPLETED NA 42 participants

Providing Evidence-Based Approaches for Caregiver Stress Study

Johns Hopkins Bloomberg School of Public Health

NCT06451250

COMPLETED NA 38 participants

Assessing a Novel Virtual Environment That Assists With Activities of Daily Living

mandy

NCT05418296

COMPLETED 37 participants

Daily Study of Caregiving Relationships and Health

The University of Texas Health Science Center at San Antonio

NCT04682535

COMPLETED 32 participants

Family Involvement Hospital Ethnography

Duke University

NCT06374992

COMPLETED NA 31 participants

CAPABLE Transitions: A Home Health-Based Intervention for the Hospital or Post-Acute Care Facility-to-Home Transition

University of Rochester

NCT04460742

COMPLETED NA 30 participants

Socially Isolated Older Adults Living With Dementia

University of Washington

NCT03666624

COMPLETED 30 participants

Connectomics in Psychiatric Classification

Washington University School of Medicine

NCT03967535

COMPLETED NA 27 participants

Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment

University of Texas Southwestern Medical Center

NCT05564715

COMPLETED NA 26 participants

SimpleC Wellness Platform With Social Robot Interaction

SimpleC

NCT05296239

COMPLETED NA 25 participants

Movement Intervention for Memory Enhancement

Albert Einstein College of Medicine

NCT03475316

COMPLETED NA 21 participants

Patient Priorities Care for Hispanics With Dementia

The University of Texas Medical Branch, Galveston

NCT05303194

COMPLETED Phase 2 20 participants

Double Blind Trial of DC Polarization in FTD

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00117858

COMPLETED NA 20 participants

Brain Changes With Game Training in Aging

University of Wisconsin, Madison

NCT02490137

COMPLETED Phase 2 20 participants

Effect of Insulin Sensitizer Metformin on AD Biomarkers

University of Pennsylvania

NCT01965756

COMPLETED NA 20 participants

Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia

Johns Hopkins University

NCT00294554

COMPLETED NA 20 participants

Paired Integrative Home Exercise for Seniors With Dementia and Their Caregivers (PairedPLIE)

University of California, San Francisco

NCT02403752

COMPLETED NA 20 participants

Zolpidem CR and Hospitalized Patients With Dementia

Massachusetts General Hospital

NCT00814502

COMPLETED NA 20 participants

"Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program"

Alzheimer's Disease Cooperative Study (ADCS)

NCT05350410

COMPLETED NA 19 participants

Pilot Mobile for Dementia and Frailty

University of Washington

NCT05827094

COMPLETED NA 18 participants

Rhythmically Entrained Exercise in Community-Dwelling Older Adults

University of North Carolina, Greensboro

NCT05462977

COMPLETED NA 18 participants

Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living

Vanderbilt University

NCT05956665

COMPLETED NA 15 participants

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes

University of California, Berkeley

NCT05159583

COMPLETED NA 14 participants

Our Care Wishes - Dementia

University of Pennsylvania

NCT05033262

COMPLETED Phase 4 12 participants

Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder

Baylor Research Institute

NCT03817931

COMPLETED Phase 4 11 participants

Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)

VA Office of Research and Development

NCT00385684

COMPLETED NA 10 participants

Enhancing Health and Quality of Life for Individuals With Dementia Through Transitional-State Snacks

University of Oregon

NCT05007730

COMPLETED Phase 1 10 participants

Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine

Mayo Clinic

NCT02131545

COMPLETED NA 6 participants

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes

University of California, Berkeley

NCT05159596

COMPLETED NA 4 participants

Yoga for Caregivers and Persons With Dementia

Wake Forest University Health Sciences

NCT05103839

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 19
Phase 3 10
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dementia Trial Landscape

202 indexed Dementia studies · 79 recruiting (39%).

Phase mix: 13 late (III/IV) vs 29 early (I/II).

Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dementia?

PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dementia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.