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Dementia: early-phase trial registry
79 of 202 indexed Dementia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #48 of 28,707 conditions by registered trial count.
202 US clinical trials · 79 currently recruiting · #48 of 28,707 conditions by registered trial count
Dementia: 202 US clinical trials tracked, 79 recruiting.
Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.
Enrollment posture brief
Registry condition dementia
OPEN 79 | RECR 39% | LATE 13 | EARLY 29 | RANK #48 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Advanced Non-Small-Cell Lung Cancer (39% recruiting · 23 trials)
Dementia lists 79 open slots (39% of 202 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Dementia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Dementia is recruiting above its size-band peers.
79 of 202 indexed trials (39.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Dementia trials is spread across many organizations.
University of Washington accounts for 8 of 202 trials (4%). 110 distinct sponsors appear on at least one study for this condition label.
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Typical Dementia enrolment sits around 154 participants.
Median target enrolment is 154 among the 200 trials that report a genuine target (sentinel values excluded). 80 of those (40%) plan for fewer than 100 participants.
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Dementia research is mostly interventional.
157 interventional and 45 observational studies make up this index (77.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
202 total, page 4 of 5
Efficacy of Early Stage Alzheimer's Support Groups
University of Washington
NCT00391794
iCare Stress Management e-Training for Dementia Family Caregivers
Photozig
NCT01378195
Tools for Distance Delivery of an Evidence-based AD Family Caregiver Intervention
NYU Langone Health
NCT02347202
Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
Otsuka Pharmaceutical Development & Commercialization
NCT00095719
Anticipating Decline and Providing Therapy
Wake Forest University Health Sciences
NCT06182995
PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in Frontotemporal Dementia
National Institute of Mental Health (NIMH)
NCT00613119
High Intensity Light Therapy in Alzheimer's Disease
National Center for Complementary and Integrative Health (NCCIH)
NCT00065689
Encouraging Cognitive Screenings at African American Churches
University of Kansas Medical Center
NCT05037578
A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
Eli Lilly and Company
NCT04640077
Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI
University of Alabama at Birmingham
NCT03734289
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
VA Office of Research and Development
NCT02350127
Community-based Brain Health Program to Address Dementia Risk
Posit Science Corporation
NCT05529706
Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers
Elizabeth K Rhodus
NCT05202223
Caregiver Study Dr. Phillips
AdventHealth
NCT03653871
A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease
CuraSen Therapeutics
NCT05104463
Effect of Treating Sleep Apnea on Cognition in Patients With Dementia
University of California, San Diego
NCT00477828
Families Affected by Dementia: A Survey of Caregivers
University of Miami
NCT02095327
Powerful Tools for Caregivers of Dementia Patients
Florida State University
NCT02697721
Effects on Dementia Caregivers
University of Central Florida
NCT06473571
Training and Coaching to Promote High Performance in Veteran Affairs (VA) Nursing Home Care
US Department of Veterans Affairs
NCT00875706
Distance Savvy: Testing Tele-Savvy, a Distance Dementia Family Caregiver Education Program
Emory University
NCT02300584
Providing Evidence-Based Approaches for Caregiver Stress Study
Johns Hopkins Bloomberg School of Public Health
NCT06451250
Assessing a Novel Virtual Environment That Assists With Activities of Daily Living
mandy
NCT05418296
Daily Study of Caregiving Relationships and Health
The University of Texas Health Science Center at San Antonio
NCT04682535
Family Involvement Hospital Ethnography
Duke University
NCT06374992
CAPABLE Transitions: A Home Health-Based Intervention for the Hospital or Post-Acute Care Facility-to-Home Transition
University of Rochester
NCT04460742
Socially Isolated Older Adults Living With Dementia
University of Washington
NCT03666624
Connectomics in Psychiatric Classification
Washington University School of Medicine
NCT03967535
Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
University of Texas Southwestern Medical Center
NCT05564715
SimpleC Wellness Platform With Social Robot Interaction
SimpleC
NCT05296239
Movement Intervention for Memory Enhancement
Albert Einstein College of Medicine
NCT03475316
Patient Priorities Care for Hispanics With Dementia
The University of Texas Medical Branch, Galveston
NCT05303194
Double Blind Trial of DC Polarization in FTD
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00117858
Brain Changes With Game Training in Aging
University of Wisconsin, Madison
NCT02490137
Effect of Insulin Sensitizer Metformin on AD Biomarkers
University of Pennsylvania
NCT01965756
Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
Johns Hopkins University
NCT00294554
Paired Integrative Home Exercise for Seniors With Dementia and Their Caregivers (PairedPLIE)
University of California, San Francisco
NCT02403752
Zolpidem CR and Hospitalized Patients With Dementia
Massachusetts General Hospital
NCT00814502
"Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program"
Alzheimer's Disease Cooperative Study (ADCS)
NCT05350410
Pilot Mobile for Dementia and Frailty
University of Washington
NCT05827094
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
University of North Carolina, Greensboro
NCT05462977
Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
Vanderbilt University
NCT05956665
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes
University of California, Berkeley
NCT05159583
Our Care Wishes - Dementia
University of Pennsylvania
NCT05033262
Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder
Baylor Research Institute
NCT03817931
Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)
VA Office of Research and Development
NCT00385684
Enhancing Health and Quality of Life for Individuals With Dementia Through Transitional-State Snacks
University of Oregon
NCT05007730
Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine
Mayo Clinic
NCT02131545
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes
University of California, Berkeley
NCT05159596
Yoga for Caregivers and Persons With Dementia
Wake Forest University Health Sciences
NCT05103839
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 19 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Dementia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Dementia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Dementia page
202 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 79 Dementia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Washington sponsors the most Dementia trials on record, review their full trial history before evaluating a specific study. See University of Washington's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dementia condition card totals 202 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.