Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Dementia clinical trials
79 of 202 indexed Dementia trials are currently recruiting.
202 US clinical trials · 79 currently recruiting
Dementia is the subject of 202 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 8 of these trials.
The research picture
Dementia has 202 registered US clinical trials, 79 of them open to new participants right now, about 39% of the total.
- 79
- recruiting participants now
- 39%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Washington
Active & Recent Trials
202 total, page 4 of 5
Efficacy of Early Stage Alzheimer's Support Groups
University of Washington
NCT00391794
iCare Stress Management e-Training for Dementia Family Caregivers
Photozig
NCT01378195
Tools for Distance Delivery of an Evidence-based AD Family Caregiver Intervention
NYU Langone Health
NCT02347202
Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
Otsuka Pharmaceutical Development & Commercialization
NCT00095719
Anticipating Decline and Providing Therapy
Wake Forest University Health Sciences
NCT06182995
PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in Frontotemporal Dementia
National Institute of Mental Health (NIMH)
NCT00613119
High Intensity Light Therapy in Alzheimer's Disease
National Center for Complementary and Integrative Health (NCCIH)
NCT00065689
Encouraging Cognitive Screenings at African American Churches
University of Kansas Medical Center
NCT05037578
A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
Eli Lilly and Company
NCT04640077
Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI
University of Alabama at Birmingham
NCT03734289
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
VA Office of Research and Development
NCT02350127
Community-based Brain Health Program to Address Dementia Risk
Posit Science Corporation
NCT05529706
Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers
Elizabeth K Rhodus
NCT05202223
Caregiver Study Dr. Phillips
AdventHealth
NCT03653871
A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease
CuraSen Therapeutics
NCT05104463
Effect of Treating Sleep Apnea on Cognition in Patients With Dementia
University of California, San Diego
NCT00477828
Families Affected by Dementia: A Survey of Caregivers
University of Miami
NCT02095327
Powerful Tools for Caregivers of Dementia Patients
Florida State University
NCT02697721
Effects on Dementia Caregivers
University of Central Florida
NCT06473571
Training and Coaching to Promote High Performance in Veteran Affairs (VA) Nursing Home Care
US Department of Veterans Affairs
NCT00875706
Distance Savvy: Testing Tele-Savvy, a Distance Dementia Family Caregiver Education Program
Emory University
NCT02300584
Providing Evidence-Based Approaches for Caregiver Stress Study
Johns Hopkins Bloomberg School of Public Health
NCT06451250
Assessing a Novel Virtual Environment That Assists With Activities of Daily Living
mandy
NCT05418296
Daily Study of Caregiving Relationships and Health
The University of Texas Health Science Center at San Antonio
NCT04682535
Family Involvement Hospital Ethnography
Duke University
NCT06374992
CAPABLE Transitions: A Home Health-Based Intervention for the Hospital or Post-Acute Care Facility-to-Home Transition
University of Rochester
NCT04460742
Socially Isolated Older Adults Living With Dementia
University of Washington
NCT03666624
Connectomics in Psychiatric Classification
Washington University School of Medicine
NCT03967535
Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
University of Texas Southwestern Medical Center
NCT05564715
SimpleC Wellness Platform With Social Robot Interaction
SimpleC
NCT05296239
Movement Intervention for Memory Enhancement
Albert Einstein College of Medicine
NCT03475316
Patient Priorities Care for Hispanics With Dementia
The University of Texas Medical Branch, Galveston
NCT05303194
Double Blind Trial of DC Polarization in FTD
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00117858
Brain Changes With Game Training in Aging
University of Wisconsin, Madison
NCT02490137
Effect of Insulin Sensitizer Metformin on AD Biomarkers
University of Pennsylvania
NCT01965756
Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
Johns Hopkins University
NCT00294554
Paired Integrative Home Exercise for Seniors With Dementia and Their Caregivers (PairedPLIE)
University of California, San Francisco
NCT02403752
Zolpidem CR and Hospitalized Patients With Dementia
Massachusetts General Hospital
NCT00814502
"Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program"
Alzheimer's Disease Cooperative Study (ADCS)
NCT05350410
Pilot Mobile for Dementia and Frailty
University of Washington
NCT05827094
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
University of North Carolina, Greensboro
NCT05462977
Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
Vanderbilt University
NCT05956665
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes
University of California, Berkeley
NCT05159583
Our Care Wishes - Dementia
University of Pennsylvania
NCT05033262
Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder
Baylor Research Institute
NCT03817931
Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)
VA Office of Research and Development
NCT00385684
Enhancing Health and Quality of Life for Individuals With Dementia Through Transitional-State Snacks
University of Oregon
NCT05007730
Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine
Mayo Clinic
NCT02131545
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes
University of California, Berkeley
NCT05159596
Yoga for Caregivers and Persons With Dementia
Wake Forest University Health Sciences
NCT05103839
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 19 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dementia Trial Landscape
202 indexed Dementia studies · 79 recruiting (39%).
Phase mix: 13 late (III/IV) vs 29 early (I/II).
Top sponsor: University of Washington (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dementia?
PlainTrial tracks 202 US clinical trials for Dementia, of which 79 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dementia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.