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NCT00294554 · ClinicalTrials.gov registry record · NA
Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
A NA study of Dementia and Parkinson's Disease, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT00294554: Completed NA study of Dementia and Parkinson's Disease, sponsored by Johns Hopkins University.
NCT00294554 is a NA study of Dementia and Parkinson's Disease that has completed, run by Johns Hopkins University. The registered enrollment target is 20 participants, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00294554, a NA study of Dementia and Parkinson's Disease, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to evaluate the usefulness of memantine, compared to placebo (sugar pill), for the treatment of cognitive impairment in patients with idiopathic Parkinson's disease (PD) and dementia. Memantine is used as a safe and effective treatment for patients with Alzheimer's disease. Cognitive impairment includes concentration and memory difficulties. We will look at how well this medication helps your cognitive impairment, how well you tolerate this medication (including its effects on your motor symptoms of PD) your activities of daily living, your emotions, and any medical conditions you might have. We will interview a person you choose as your "informant".
Primary Outcome
The DRS is comprised of: Attention (ATT, 8 items); Initiation-Perseveration (I-P, 11 items); Construction (CONST, 6 items); Conceptualization (CONCEPT, 6 items); and Memory (MEM, 5 items). For this study, only the memory subscore was used, with score possibilities ranging from 0-5, with 5 meaning memory was perfect, 0 being no ability to recall. A negative score indicates a decrease in memory from baseline to 24 weeks.
Conditions Studied
Interventions
- DRUG Placebo Oral Tablet
- DRUG Memantine
Study Locations (1)
Maryland
- Johns Hopkins Hospital - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2006-04 |
| Est. Completion | 2008-12 |
| Phase | NA |
What the finished NCT00294554 record still lists
NCT00294554 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Dementia appearing as the primary indexed condition, and to 2 interventions - of which Placebo Oral Tablet is the first listed.
NCT00294554 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00294554 about?
NCT00294554 is a clinical study titled "Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia". The purpose of this research is to evaluate the usefulness of memantine, compared to placebo (sugar pill), for the treatment of cognitive impairment in patients with idiopathic Parkinson's disease (PD) and dementia. Memantine is used as a safe and effective treatment for patients with Alzheimer's di...
What is the current status of trial NCT00294554?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2006-04. Estimated completion is 2008-12.
What conditions does trial NCT00294554 study?
This clinical trial studies the following conditions: Dementia, Parkinson's Disease, Cognitive Impairment.
What interventions are being tested in trial NCT00294554?
The interventions under investigation include: Placebo Oral Tablet (DRUG), Memantine (DRUG).
Who is sponsoring clinical trial NCT00294554?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00294554 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dementia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00294554's enrollment target sits among peer trials
20 180th of 199 higher than 12 of 199 other Dementia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dementia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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