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NCT02350127 · ClinicalTrials.gov registry record · Phase 2
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
A Phase 2 study of Dementia and Alzheimers Disease, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- Phase 2
- Development phase
- 88
- Enrollment target
- 1
- Study location
NCT02350127: Completed Phase 2 study of Dementia and Alzheimers Disease, sponsored by VA Office of Research and Development.
NCT02350127 is a Phase 2 study of Dementia and Alzheimers Disease that has completed, run by VA Office of Research and Development. The registered enrollment target is 88 participants, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02350127, a Phase 2 study of Dementia and Alzheimers Disease, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course. Therefore, it is critically important to identify effective strategies for helping older Veterans living with dementia to enhance their functional status and quality of life. The investigators have developed a novel, integrative group movement program called Preventing Loss of Independence through Exercise (PLIE) that incorporates elements from Eastern and Western exercise modalities and is designed to build and maintain the capacity to perform basic functional movements while increasing mindful body awareness and enhancing social connection. Pilot study results suggested that PLIE is associated with meaningful improvements in physical function, cognitive function and quality of life as well as reduced caregiver burden. The goal of the current study is to perform a full-scale randomized, controlled trial to test the efficacy of PLIE in older Veterans with dementia.
Primary Outcome
The Quality of Life Scale in Alzheimer's Disease (QOL-AD) is a standard quality of life measure that asks parallel questions of affected individuals and caregivers. Current quality of life is rated as poor (1 point), fair (2 points), good (3 points) or excellent (4 points) in 13 areas: physical health, energy, mood, living situation, memory, family, marriage, friends, self as a whole, ability to do chores around the house, ability to do things for fun, money, and life as a whole. Scores may rang
Conditions Studied
Interventions
- BEHAVIORAL Usual Care
- BEHAVIORAL Preventing Loss of Independence through Exercise (PLIE)
Study Locations (1)
California
- San Francisco VA Medical Center, San Francisco, CA - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2015-05-04 |
| Est. Completion | 2018-12-31 |
| Phase | Phase 2 |
What the finished NCT02350127 record still lists
NCT02350127 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Dementia appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.
NCT02350127 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT02350127 about?
NCT02350127 is a clinical study titled "Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia". Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course. Therefore, it is critically important to identify effective strategies for h...
What is the current status of trial NCT02350127?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2015-05-04. Estimated completion is 2018-12-31.
What conditions does trial NCT02350127 study?
This clinical trial studies the following conditions: Dementia, Alzheimers Disease.
What interventions are being tested in trial NCT02350127?
The interventions under investigation include: Usual Care (BEHAVIORAL), Preventing Loss of Independence through Exercise (PLIE) (BEHAVIORAL).
Who is sponsoring clinical trial NCT02350127?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02350127 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02350127's enrollment target sits among peer trials
88 125th of 199 higher than 74 of 199 other Dementia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dementia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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