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NCT02350127 · ClinicalTrials.gov registry record · Phase 2

Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia

A Phase 2 study of Dementia and Alzheimers Disease, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 2
Development phase
88
Enrollment target
1
Study location

NCT02350127 is a Phase 2 study of Dementia and Alzheimers Disease that has completed, run by VA Office of Research and Development. The registered enrollment target is 88 participants, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02350127, a Phase 2 study of Dementia and Alzheimers Disease, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 2
Development phase
88 participants
Enrollment target
1
Study location

Study Summary

Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course. Therefore, it is critically important to identify effective strategies for helping older Veterans living with dementia to enhance their functional status and quality of life. The investigators have developed a novel, integrative group movement program called Preventing Loss of Independence through Exercise (PLIE) that incorporates elements from Eastern and Western exercise modalities and is designed to build and maintain the capacity to perform basic functional movements while increasing mindful body awareness and enhancing social connection. Pilot study results suggested that PLIE is associated with meaningful improvements in physical function, cognitive function and quality of life as well as reduced caregiver burden. The goal of the current study is to perform a full-scale randomized, controlled trial to test the efficacy of PLIE in older Veterans with dementia.

Interventions

  • BEHAVIORAL Usual Care
  • BEHAVIORAL Preventing Loss of Independence through Exercise (PLIE)

Study Locations (1)

California

  • San Francisco VA Medical Center, San Francisco, CA - San Francisco

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2015-05-04
Est. Completion 2018-12-31
Phase Phase 2

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT02350127

The ClinicalTrials.gov registry entry for NCT02350127 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,723-participant average among 199 other Dementia trials with a reported enrollment target (99% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Dementia appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.

NCT02350127 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT02350127 about?

NCT02350127 is a clinical study titled "Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia". Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course. Therefore, it is critically important to identify effective strategies for h...

What is the current status of trial NCT02350127?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2015-05-04. Estimated completion is 2018-12-31.

What conditions does trial NCT02350127 study?

This clinical trial studies the following conditions: Dementia, Alzheimers Disease.

What interventions are being tested in trial NCT02350127?

The interventions under investigation include: Usual Care (BEHAVIORAL), Preventing Loss of Independence through Exercise (PLIE) (BEHAVIORAL).

Who is sponsoring clinical trial NCT02350127?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02350127 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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