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NCT05564715 · ClinicalTrials.gov registry record · NA
Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
A NA study of Mild Cognitive Impairment and Dementia, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 27
- Enrollment target
- 1
- Study location
NCT05564715: Completed NA study of Mild Cognitive Impairment and Dementia, sponsored by University of Texas Southwestern Medical Center.
NCT05564715 is a NA study of Mild Cognitive Impairment and Dementia that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 27 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05564715, a NA study of Mild Cognitive Impairment and Dementia, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot study being done to attempt to improve episodic memory problems in persons with mild cognitive impairment (MCI) or dementia. The pre-supplemental motor area (preSMA) and dorsal anterior cingulate cortex (dACC) have been shown to play a role in episodic memory and language retrieval. Prior studies have suggested that neurostimulation targeting this region can improve episodic memory and word recall. The purpose of this study is to examine the efficacy of high-definition transcranial direct current stimulation (HD-tDCS) to the preSMA/dACC region and its influence on word retrieval and other cognitive functions in patients with MCI or dementia. Entraining the preSMA/dACC circuit with 10 sessions of HD-tDCS will allow us to study whether neurostimulation may be an effective treatment.
Primary Outcome
The RAVLT is a verbal episodic memory test that is sensitive to mesial and lateral verbal episodic memory circuit dysfunction. The primary outcome measure for this task is the total number of items immediately recalled during the learning trials and after the 30 minute delayed recall trial. Changes in scores from baseline to testing immediately following the completion of the condition will be examined as well as from baseline to 8 weeks post-treatment. RAVLT : Rey Auditory Verbal Learning Test
Conditions Studied
Interventions
- DEVICE Sham Treatment
- DEVICE NeuroElectric StarStim
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2023-05-01 |
| Est. Completion | 2025-06-03 |
| Phase | NA |
What the finished NCT05564715 record still lists
NCT05564715 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Sham Treatment is the first listed.
NCT05564715 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05564715 about?
NCT05564715 is a clinical study titled "Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment". This is a pilot study being done to attempt to improve episodic memory problems in persons with mild cognitive impairment (MCI) or dementia. The pre-supplemental motor area (preSMA) and dorsal anterior cingulate cortex (dACC) have been shown to play a role in episodic memory and language retrieval. ...
What is the current status of trial NCT05564715?
This trial is currently completed. It is a NA study. The enrollment target is 27 participants. The study started on 2023-05-01. Estimated completion is 2025-06-03.
What conditions does trial NCT05564715 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Dementia, Amnestic Mild Cognitive Impairment - aMCI.
What interventions are being tested in trial NCT05564715?
The interventions under investigation include: Sham Treatment (DEVICE), NeuroElectric StarStim (DEVICE).
Who is sponsoring clinical trial NCT05564715?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05564715 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05564715's enrollment target sits among peer trials
27 170th of 205 higher than 36 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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