Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
COPD: full-pipeline trial registry
28 of 86 indexed COPD trials are currently recruiting.
Corpus placement: #160 of 28,707 conditions by registered trial count.
86 US clinical trials · 28 currently recruiting · #160 of 28,707 conditions by registered trial count
COPD: 86 US clinical trials tracked, 28 recruiting.
COPD is the subject of 86 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 6 of these trials.
Enrollment posture brief
Registry condition copd
OPEN 28 | RECR 33% | LATE 11 | EARLY 12 | RANK #160 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Recurrent Ovarian Carcinoma (33% recruiting · 40 trials)
COPD lists 28 open slots (33% of 86 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for COPD on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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COPD is recruiting below its size-band peers.
28 of 86 indexed trials (32.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of COPD trials is spread across many organizations.
VA Office of Research and Development accounts for 6 of 86 trials (7%). 63 distinct sponsors appear on at least one study for this condition label.
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Typical COPD enrolment sits around 74 participants.
Median target enrolment is 74 among the 86 trials that report a genuine target (sentinel values excluded). 47 of those (54.7%) plan for fewer than 100 participants.
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COPD research is mostly interventional.
66 interventional and 20 observational studies make up this index (76.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
86 total, page 2 of 2
Alpha-1 Carrier Genomics Study
Medical University of South Carolina
NCT02810327
Healthy At Home Pilot
University of Massachusetts, Worcester
NCT06000696
Effect of Nebulized Bronchodilators on Heart Rate
Fahim Khorfan, MD
NCT01151579
A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
Centocor
NCT00380796
Monitoring Metered Dose Inhalation (MDI) Volume and Timing With a Respimetrix Device in Obstructive Lung Disease.
Pulmonary Critical Care Associates of Baltimore
NCT05495256
Functional Proteomics of Alveolar Macrophages
Ohio State University
NCT00806091
At Home Spirometry and Video Module Education for COPD Patients
University of Chicago
NCT03834350
A 7-Day Cross-over Study of QD (Once Daily) and BID (Twice Daily) TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Mylan
NCT02109172
MagniXene MRI Use in Patients With Asthma and COPD to Assess Regional Lung Function by Delineating Ventilation Defects
Xemed
NCT01833390
Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)
Johns Hopkins University
NCT01764165
Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
Johns Hopkins University
NCT00181207
Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT
University of Alabama at Birmingham
NCT05040386
Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen
Hal C Charles
NCT01710449
Integrative-omics of the Disordered COPD Small Airway Epithelium
Weill Medical College of Cornell University
NCT02183818
Vector Engineering Clinical
Philips Clinical & Medical Affairs Global
NCT04725500
Capnography-Assisted Learned Monitored (CALM) Breathing Therapy for COPD
Columbia University
NCT04786184
Randomized Controlled Eight-Week Study of the Safety and Efficacy of the Lung Flute
Medical Acoustics
NCT00560105
Rehabilitation of Patients With COPD Using Electrical Muscle Stimulation
Yale University
NCT01799330
A Phase I Study of iPS Cell Generation From Patients With COPD
Mayo Clinic
NCT01860898
Peak Inspiratory Flow and Dry Powder Inhaler Performance in COPD
Pulmonary Research Institute of Southeast Michigan
NCT04606394
Effect of Statin Therapy on C-reactive Protein Levels in Patients With Chronic Obstructive Lung Disease (COPD)
VA Loma Linda Health Care System
NCT00655993
Evaluation of Muscle Activation Efficiency in Challenging Subjects
Niveus Medical
NCT01811446
A Placebo-controlled Trial of Daliresp on Chronic Obstructive Pulmonary Disease (COPD)
University of Alabama at Birmingham
NCT01572948
The Trajectory of Physical Activity Following Pulmonary Rehabilitation
Trinity Health Of New England
NCT02399254
Interleukin-5 Receptor Expression in COPD
University of Virginia
NCT03984799
Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD)
Trinity Health Of New England
NCT00773786
Mindfulness Based Stress Reduction in COPD
Mayo Clinic
NCT01058499
Real-Time Support for Exercise Persistence in COPD
University of Washington
NCT00373932
Static Lung Hyperinflation and Sympathetic Nerve Activity-Associated Large Artery Stiffness in COPD Patients
Gary L. Pierce
NCT03611699
Innovative Pulmonary Rehabilitation Telehealth Program for Improving COPD Patient Outcomes
University of Kansas Medical Center
NCT03489642
Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study
The Cooper Health System
NCT00401206
Respiratory Disorders Non-invasive Monitoring of Work of Breathing in Outpatients
Stanford University
NCT04003415
Device-guided Breathing for Shortness of Breath in COPD
Mayo Clinic
NCT01286181
BRAIN, Symptoms, and Physical Activity in COPD
VA Office of Research and Development
NCT04291131
Study to Assess the Safety and Tolerability of Incremental Doses of QAB149 in Adults With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD)
Novartis
NCT00129831
A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients
Mayo Clinic
NCT03814980
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 3 | 3 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on COPD records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on COPD trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this COPD page
86 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 28 COPD trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most COPD trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This COPD condition card totals 86 registered trials; most-linked intervention Placebo; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.