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NCT03611699 · ClinicalTrials.gov registry record · Phase 4

Static Lung Hyperinflation and Sympathetic Nerve Activity-Associated Large Artery Stiffness in COPD Patients

A Phase 4 study of COPD, sponsored by Gary L. Pierce.

Completed
Registry status
Phase 4
Development phase
15
Enrollment target
1
Study location

NCT03611699 is a Phase 4 study of COPD that has completed, run by Gary L. Pierce. The registered enrollment target is 15 participants, below the 2,418-participant average among 85 other COPD trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03611699, a Phase 4 study of COPD, has completed, sponsored by Gary L. Pierce.

COMPLETED
Registry status
Phase 4
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to evaluate the acute effects of a long-acting bronchodilator on pulmonary function, vascular function and muscle sympathetic nerve activity in individuals with COPD. Individuals will be recruited from previous pulmonary research cohorts at The University of Iowa hospitals and clinics. Individuals that are interested in the study and are deemed eligible to participate will have a total of 3 visits to the laboratory, which includes the screening and consent (visit 1) that will last approximately 1 hour. Visits 2 and 3 are experimental visits and will be more extensive (\~4 hours). Participants will be randomized to receive either a long-acting bronchodilator or a placebo inhaler at the first experimental visit, followed by either the placebo inhaler or the long-acting bronchodilator at the second experimental visit. Assessments of pulmonary function, vascular function (via non-invasive, well-established techniques), and muscle sympathetic nerve activity will be performed at both experimental visits.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Umeclidinium / Vilanterol Dry Powder Inhaler

Study Locations (1)

Iowa

  • The University of Iowa Hospital and Clinics - Iowa City

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2019-01-24
Est. Completion 2020-04-01
Phase Phase 4

Sponsor

Gary L. Pierce

4 total trials

What the Registry Record Tells You About NCT03611699

The ClinicalTrials.gov registry entry for NCT03611699 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,418-participant average among 85 other COPD trials with a reported enrollment target (99% lower). The listed sponsor is Gary L. Pierce, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with COPD appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03611699 reports 1 study location spanning 1 distinct geographic area - top geographies include Iowa.

Frequently Asked Questions

What is clinical trial NCT03611699 about?

NCT03611699 is a clinical study titled "Static Lung Hyperinflation and Sympathetic Nerve Activity-Associated Large Artery Stiffness in COPD Patients". The goal of this study is to evaluate the acute effects of a long-acting bronchodilator on pulmonary function, vascular function and muscle sympathetic nerve activity in individuals with COPD. Individuals will be recruited from previous pulmonary research cohorts at The University of Iowa hospitals ...

What is the current status of trial NCT03611699?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2019-01-24. Estimated completion is 2020-04-01.

What conditions does trial NCT03611699 study?

This clinical trial studies the following conditions: COPD.

What interventions are being tested in trial NCT03611699?

The interventions under investigation include: Placebo (DRUG), Umeclidinium / Vilanterol Dry Powder Inhaler (DRUG).

Who is sponsoring clinical trial NCT03611699?

This trial is sponsored by Gary L. Pierce, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03611699 being conducted?

This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.