Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cognitive Decline: early-phase trial registry
36 of 62 indexed Cognitive Decline trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #228 of 28,707 conditions by registered trial count.
62 US clinical trials · 36 currently recruiting · #228 of 28,707 conditions by registered trial count
Cognitive Decline: 62 US clinical trials tracked, 36 recruiting.
Cognitive Decline is the subject of 62 registered US clinical trials on ClinicalTrials.gov, 36 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is C2N Diagnostics, running 2 of these trials.
Enrollment posture brief
Registry condition cognitive-decline
OPEN 36 | RECR 58% | LATE 2 | EARLY 8 | RANK #228 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Infant Development (58% recruiting · 31 trials)
Cognitive Decline lists 36 open slots (58% of 62 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cognitive Decline on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cognitive Decline is recruiting above its size-band peers.
36 of 62 indexed trials (58.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cognitive Decline trials is spread across many organizations.
C2N Diagnostics accounts for 2 of 62 trials (3.2%). 53 distinct sponsors appear on at least one study for this condition label.
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Typical Cognitive Decline enrolment sits around 150 participants.
Median target enrolment is 150 among the 62 trials that report a genuine target (sentinel values excluded). 19 of those (30.6%) plan for fewer than 100 participants.
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Cognitive Decline research is mostly interventional.
49 interventional and 13 observational studies make up this index (79% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
62 total, page 2 of 2
The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults with Hypertension (ACTION)
University of Connecticut
NCT04384263
Quality Improvement PrecivityAD Clinician Survey (QUIP I)
C2N Diagnostics
NCT05477056
Establishing Clinical Utility Evidence for a Novel Alzheimer's Disease Blood-Based Biomarker Assay
Qure Healthcare
NCT07099001
Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study
Neil M Rofsky, MD, MHA
NCT04080544
Preoperative Cognitive Reserve in Older Surgical Patients: A Feasibility Study
Ohio State University
NCT06245005
Noninvasive Brain Stimulation for Mild Cognitive Impairment
Palo Alto Veterans Institute for Research
NCT03331796
Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults
Brigham and Women's Hospital
NCT05764824
Digital Cognition in Multiple Sclerosis
University of California, San Francisco
NCT03569618
Preventing Cognitive Decline
Arizona State University
NCT05446909
Movement Intervention for Memory Enhancement
Albert Einstein College of Medicine
NCT03475316
Brain Vascular and Neurocognitive Health
The University of Texas at Arlington
NCT06497413
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
University of North Carolina, Greensboro
NCT05462977
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Cognitive Decline records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cognitive Decline trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cognitive Decline page
62 registered trials, 36 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 36 Cognitive Decline trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- C2N Diagnostics sponsors the most Cognitive Decline trials on record, review their full trial history before evaluating a specific study. See C2N Diagnostics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cognitive Decline condition card totals 62 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.