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NCT04080544 · ClinicalTrials.gov registry record · Phase 2

Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study

A Phase 2 study of Alzheimer Disease and Cognitive Decline, sponsored by Neil M Rofsky, MD, MHA.

Completed
Registry status
Phase 2
Development phase
125
Enrollment target
1
Study location

NCT04080544 is a Phase 2 study of Alzheimer Disease and Cognitive Decline that has completed, run by Neil M Rofsky, MD, MHA. The registered enrollment target is 125 participants, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04080544, a Phase 2 study of Alzheimer Disease and Cognitive Decline, has completed, sponsored by Neil M Rofsky, MD, MHA.

COMPLETED
Registry status
Phase 2
Development phase
125 participants
Enrollment target
1
Study location

Study Summary

The investigators will conduct tau positron emission tomography (PET) scans on 125 adults using the radiopharmaceutical Flortaucipir F18 (\[18F\]AV-1451). This will allow the investigators to determine tau deposition across adults of different ages and assess the relationship of current tau burden to cognitive function and amyloid deposition collected over the previous 10-year interval.

Interventions

  • PROCEDURE Positron Emission Tomography
  • DRUG [18F]AV-1451

Study Locations (1)

Texas

  • UT Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 125 participants
Start Date 2019-01-15
Est. Completion 2022-06-30
Phase Phase 2

Sponsor

Neil M Rofsky, MD, MHA

1 total trials

What the Registry Record Tells You About NCT04080544

The ClinicalTrials.gov registry entry for NCT04080544 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 125 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (95% lower). The listed sponsor is Neil M Rofsky, MD, MHA, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which Positron Emission Tomography is the first listed.

NCT04080544 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT04080544 about?

NCT04080544 is a clinical study titled "Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study". The investigators will conduct tau positron emission tomography (PET) scans on 125 adults using the radiopharmaceutical Flortaucipir F18 (\[18F\]AV-1451). This will allow the investigators to determine tau deposition across adults of different ages and assess the relationship of current tau burden t...

What is the current status of trial NCT04080544?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 125 participants. The study started on 2019-01-15. Estimated completion is 2022-06-30.

What conditions does trial NCT04080544 study?

This clinical trial studies the following conditions: Alzheimer Disease, Cognitive Decline.

What interventions are being tested in trial NCT04080544?

The interventions under investigation include: Positron Emission Tomography (PROCEDURE), [18F]AV-1451 (DRUG).

Who is sponsoring clinical trial NCT04080544?

This trial is sponsored by Neil M Rofsky, MD, MHA, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04080544 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.