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NCT03331796 · ClinicalTrials.gov registry record · NA
Noninvasive Brain Stimulation for Mild Cognitive Impairment
A NA study of Mild Cognitive Impairment and Cognitive Decline, sponsored by Palo Alto Veterans Institute for Research.
- Completed
- Registry status
- NA
- Development phase
- 69
- Enrollment target
- 1
- Study location
NCT03331796: Completed NA study of Mild Cognitive Impairment and Cognitive Decline, sponsored by Palo Alto Veterans Institute for Research.
NCT03331796 is a NA study of Mild Cognitive Impairment and Cognitive Decline that has completed, run by Palo Alto Veterans Institute for Research. The registered enrollment target is 69 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03331796, a NA study of Mild Cognitive Impairment and Cognitive Decline, has completed, sponsored by Palo Alto Veterans Institute for Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 69 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to test the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) as a treatment for Mild Cognitive Impairment (MCI). Participants will be randomly assigned to one of three treatment groups: Group 1: Active Dorsolateral Prefrontal Cortex (DLPFC) rTMS; Group 2: Active Lateral Parietal Cortex (LPC) rTMS; and Group 3: Inactive rTMS (Placebo) control (evenly split between each coil location). Participation in the study takes approximately 7 ½ months-including a 2-to 4-week treatment phase (20 rTMS sessions) and a 6-month follow-up phase.
Primary Outcome
The California Verbal Learning Test, Second edition (CVLT-II) is a memory task that yields several indices of the ability to learn a list of semantically related words and remember the list after a delay interval. The target list ("List A") of the CVLT-II contains 16 words. There are 5 orally presented learning trials; each is followed by immediate recall of the words in any order. The total number of words correctly recalled on the 5 list-learning trials was computed (range = 0 to 80). Higher
Conditions Studied
Interventions
- DEVICE Active rTMS (Bilateral DLPFC)
- DEVICE Active rTMS (Bilateral LPC)
- DEVICE Placebo rTMS (Inactive)
Study Locations (1)
California
- VA Palo Alto Health Care System - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2018-06-15 |
| Est. Completion | 2023-03-28 |
| Phase | NA |
What the finished NCT03331796 record still lists
NCT03331796 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 69 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (95% lower).
The record links to 8 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 3 interventions - of which Active rTMS (Bilateral DLPFC) is the first listed.
NCT03331796 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03331796 about?
NCT03331796 is a clinical study titled "Noninvasive Brain Stimulation for Mild Cognitive Impairment". The goal of this study is to test the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) as a treatment for Mild Cognitive Impairment (MCI). Participants will be randomly assigned to one of three treatment groups: Group 1: Active Dorsolateral Prefrontal Cortex (DLPFC) rTMS; Group 2: Act...
What is the current status of trial NCT03331796?
This trial is currently completed. It is a NA study. The enrollment target is 69 participants. The study started on 2018-06-15. Estimated completion is 2023-03-28.
What conditions does trial NCT03331796 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Cognitive Decline, Cognitive Dysfunction, Memory Impairment, Memory Loss.
What interventions are being tested in trial NCT03331796?
The interventions under investigation include: Active rTMS (Bilateral DLPFC) (DEVICE), Active rTMS (Bilateral LPC) (DEVICE), Placebo rTMS (Inactive) (DEVICE).
Who is sponsoring clinical trial NCT03331796?
This trial is sponsored by Palo Alto Veterans Institute for Research, which has 35 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03331796 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03331796's enrollment target sits among peer trials
69 118th of 205 higher than 87 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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