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NCT06860711 · ClinicalTrials.gov registry record · Phase 4
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
A Phase 4 study of Chronic Kidney Disease and Pediatric Urology, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06860711: Recruiting Phase 4 study of Chronic Kidney Disease and Pediatric Urology, sponsored by University of Colorado, Denver.
NCT06860711 is a Phase 4 study of Chronic Kidney Disease and Pediatric Urology that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 80 participants, below the 3,206-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06860711, a Phase 4 study of Chronic Kidney Disease and Pediatric Urology, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney disease (CKD). The investigators hypothesize that there is no increased risk. This will be a limited pilot study within a Pediatric Urology population, intended to inform future work in a larger patient population.
Primary Outcome
Acute kidney injury (AKI) will be assessed for according to Kidney Disease Improving Global Outcomes (KDIGO) criteria. Specifically, an AKI will be defined as a serum creatinine increase of ≥ 1.5 times baseline or ≥0.3 mg/dl increase within 48hrs, or a urine output \<0.5ml/kg/h for 6 to 12 hours. While there are 3 stages of AKI, the investigators will consider AKI a binary outcome since all stages are managed the same clinically. Urine output is recorded as a routine part of strict intake \& out
Conditions Studied
Interventions
- DRUG Placebo
- DRUG NSAIDs
Study Locations (1)
Colorado
- Children's Hospital Colorado - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-07-22 |
| Est. Completion | 2027-06 |
| Phase | Phase 4 |
What NCT06860711 shows while recruiting
NCT06860711 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 3,206-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Chronic Kidney Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06860711 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06860711 about?
NCT06860711 is a clinical study titled "Safety of Short-course of NSAIDs in Pediatric Patients With CKD". The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney disease (CKD). The investigators hypothesize that there is no increased ris...
What is the current status of trial NCT06860711?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2025-07-22. Estimated completion is 2027-06.
What conditions does trial NCT06860711 study?
This clinical trial studies the following conditions: Chronic Kidney Disease, Pediatric Urology.
What interventions are being tested in trial NCT06860711?
The interventions under investigation include: Placebo (DRUG), NSAIDs (DRUG).
Who is sponsoring clinical trial NCT06860711?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06860711 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Kidney Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06860711's enrollment target sits among peer trials
80 64th of 101 higher than 37 of 101 other Chronic Kidney Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Kidney Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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