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Chronic Kidney Disease clinical trials
32 of 103 indexed Chronic Kidney Disease trials are currently recruiting.
103 US clinical trials · 32 currently recruiting
Chronic Kidney Disease is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 8 of these trials.
The research picture
Chronic Kidney Disease has 103 registered US clinical trials, 32 of them open to new participants right now, about 31% of the total.
- 32
- recruiting participants now
- 31%
- of trials open to enrollment
- 27
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Bayer
Active & Recent Trials
103 total, page 2 of 3
Telemonitoring to Improve Outcomes of Patients With Chronic Kidney Disease (CKD)
Minneapolis Veterans Affairs Medical Center
NCT01446029
Is There a Digital Divide in Chronic Kidney Disease (CKD)?
Duke University
NCT03067779
Comparing Safety and Immunogenicity of HEPLISAV-B® to Engerix-B® in Chronic Kidney Disease (CKD) Patients
Dynavax Technologies Corporation
NCT00985426
The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors
Abbott
NCT00421733
Palm Tocotrienols in Chronic Hemodialysis (USA)
Wayne State University
NCT02358967
Diabetes CKD Lifestyle Technology Study
NYU Langone Health
NCT02266823
A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Bayer
NCT05901831
Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
Biogen
NCT00811889
20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
Akebia Therapeutics
NCT01906489
Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D
Denver Nephrologists, P.C.
NCT02492620
Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis
Takeda
NCT01478971
A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease
Denver Nephrologists, P.C.
NCT01475760
Study of Phosphate Levels in Patients With Chronic Kidney Disease
Vifor Pharma
NCT00824460
Vitamin D and Arterial Function in Patients With Chronic Kidney Disease
University of Colorado, Denver
NCT01384539
Metformin in Kidney Disease
VA Office of Research and Development
NCT02252081
DyeVert™ Plus Contrast Reduction System Multicenter Observational Study
Osprey Medical
NCT03715452
A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)
Novo Nordisk A/S
NCT04865770
Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)
Srinvasan Beddhu
NCT02970123
A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making
Massachusetts General Hospital
NCT02698722
Trial to Optimize Mineral Outcomes in Dialysis Patients
University of Colorado, Denver
NCT01100723
Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia
ZS Pharma
NCT01493024
Endothelial Microparticles: A Novel Marker of Vascular Dysfunction
University of Colorado, Denver
NCT02230202
A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease
Prokidney
NCT02836574
Phosphate Lowering in CKD Trial
VA Office of Research and Development
NCT02209636
Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)
Vanderbilt University
NCT00308971
Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
University of Alabama at Birmingham
NCT02888171
A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis
Novartis Pharmaceuticals
NCT00750295
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Baylor Research Institute
NCT02251431
Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes
Geisinger Clinic
NCT03015480
Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo
Amy Barton Pai
NCT00915876
Hemodialysis Vascular Access Imaging Study
Renal Research Institute
NCT02374762
Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease
University of Alabama at Birmingham
NCT01988116
Rifaximin Therapy in Chronic Kidney Disease
Jason Stubbs, MD
NCT02342639
Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects
Atlanta VA Medical Center
NCT00427037
Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
University of Colorado, Denver
NCT04600323
FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.
FAST BioMedical
NCT01978314
Study to Assess PK, Safety and Tolerability in Patients With DM and CKD
DiaMedica Therapeutics
NCT03795389
Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease
Kenneth R. Phelps, M.D.
NCT01191762
Advanced Glycation End-products, Inflammation and Vascular Health in Chronic Kidney Disease
University of Alabama at Birmingham
NCT01769963
Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease
University of Washington
NCT00552409
Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease
University of Alabama at Birmingham
NCT02497300
Multicultural Healthy Diet in Chronic Kidney Disease
Montefiore Medical Center
NCT05504850
A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease
Renibus Therapeutics
NCT04072432
Analysis of Calcium Balance in Chronic Kidney Disease
University of Colorado, Denver
NCT00974532
The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients
University of Florida
NCT01842087
Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease
Geoffrey Block
NCT01341678
Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
University of Tennessee
NCT06123195
Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease
University of California, Irvine
NCT00793806
Effects Of Darbepoetin On Vascular Repair Mechanisms In Kidney Disease The DARBEPC Study
University of Michigan
NCT00396123
A Trial of Doxycycline in Renal Disease
University of California, San Francisco
NCT02753426
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 17 |
| Phase 3 | 19 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Kidney Disease Trial Landscape
103 indexed Chronic Kidney Disease studies · 32 recruiting (31%).
Phase mix: 27 late (III/IV) vs 27 early (I/II).
Top sponsor: Bayer (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Kidney Disease?
PlainTrial tracks 103 US clinical trials for Chronic Kidney Disease, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Kidney Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.