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ClinicalTrials.gov 32 recruiting now full pipeline #130 of 28,707 conditions

Chronic Kidney Disease: full-pipeline trial registry

32 of 103 indexed Chronic Kidney Disease trials are currently recruiting.

Corpus placement: #130 of 28,707 conditions by registered trial count.

103 US clinical trials · 32 currently recruiting · #130 of 28,707 conditions by registered trial count

Chronic Kidney Disease: 103 US clinical trials tracked, 32 recruiting.

Chronic Kidney Disease is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 8 of these trials.

Enrollment posture brief

Registry condition chronic-kidney-disease

OPEN 32 | RECR 31% | LATE 27 | EARLY 27 | RANK #130 | SPON 8

Nearest open-share peer: Eosinophilic Esophagitis (31% recruiting · 45 trials)

Amyotrophic Lateral Sclerosi45.6%Mantle Cell Lymphoma44.7%Chronic Kidney Disease (this)31%Attention Deficit Hyperactiv28.2%Metabolic Syndrome26.9%
Open-enrollment share among volume-matched conditions near Chronic Kidney Disease

Chronic Kidney Disease lists 32 open slots (31% of 103 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Kidney Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Kidney Disease is recruiting below its size-band peers.

    32 of 103 indexed trials (31.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Chronic Kidney Disease trials is spread across many organizations.

    Bayer accounts for 8 of 103 trials (7.8%). 68 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Kidney Disease enrolment sits around 124 participants.

    Median target enrolment is 124 among the 102 trials that report a genuine target (sentinel values excluded). 43 of those (42.2%) plan for fewer than 100 participants.

  4. Chronic Kidney Disease research is mostly interventional.

    82 interventional and 21 observational studies make up this index (79.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 217Phase 319Phase 48

Open and recent trials

103 total, page 2 of 3

COMPLETED Phase 3 601 participants

Telemonitoring to Improve Outcomes of Patients With Chronic Kidney Disease (CKD)

Minneapolis Veterans Affairs Medical Center

NCT01446029

COMPLETED NA 580 participants

Is There a Digital Divide in Chronic Kidney Disease (CKD)?

Duke University

NCT03067779

COMPLETED Phase 3 521 participants

Comparing Safety and Immunogenicity of HEPLISAV-B® to Engerix-B® in Chronic Kidney Disease (CKD) Patients

Dynavax Technologies Corporation

NCT00985426

COMPLETED Phase 2 281 participants

The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors

Abbott

NCT00421733

COMPLETED NA 280 participants

Palm Tocotrienols in Chronic Hemodialysis (USA)

Wayne State University

NCT02358967

COMPLETED NA 270 participants

Diabetes CKD Lifestyle Technology Study

NYU Langone Health

NCT02266823

COMPLETED Phase 3 241 participants

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes

Bayer

NCT05901831

COMPLETED Phase 2 227 participants

Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease

Biogen

NCT00811889

COMPLETED Phase 2 210 participants

20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia

Akebia Therapeutics

NCT01906489

COMPLETED Phase 3 200 participants

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

Denver Nephrologists, P.C.

NCT02492620

COMPLETED Phase 3 184 participants

Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis

Takeda

NCT01478971

COMPLETED NA 167 participants

A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease

Denver Nephrologists, P.C.

NCT01475760

COMPLETED Phase 2 154 participants

Study of Phosphate Levels in Patients With Chronic Kidney Disease

Vifor Pharma

NCT00824460

COMPLETED Phase 3 128 participants

Vitamin D and Arterial Function in Patients With Chronic Kidney Disease

University of Colorado, Denver

NCT01384539

COMPLETED Phase 2 125 participants

Metformin in Kidney Disease

VA Office of Research and Development

NCT02252081

COMPLETED 114 participants

DyeVert™ Plus Contrast Reduction System Multicenter Observational Study

Osprey Medical

NCT03715452

COMPLETED Phase 3 106 participants

A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)

Novo Nordisk A/S

NCT04865770

COMPLETED NA 106 participants

Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)

Srinvasan Beddhu

NCT02970123

COMPLETED NA 100 participants

A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making

Massachusetts General Hospital

NCT02698722

COMPLETED Phase 4 92 participants

Trial to Optimize Mineral Outcomes in Dialysis Patients

University of Colorado, Denver

NCT01100723

COMPLETED Phase 2 90 participants

Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia

ZS Pharma

NCT01493024

COMPLETED 90 participants

Endothelial Microparticles: A Novel Marker of Vascular Dysfunction

University of Colorado, Denver

NCT02230202

COMPLETED Phase 2 83 participants

A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease

Prokidney

NCT02836574

COMPLETED Phase 4 66 participants

Phosphate Lowering in CKD Trial

VA Office of Research and Development

NCT02209636

COMPLETED Phase 2 62 participants

Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)

Vanderbilt University

NCT00308971

COMPLETED NA 60 participants

Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency

University of Alabama at Birmingham

NCT02888171

COMPLETED Phase 1 60 participants

A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis

Novartis Pharmaceuticals

NCT00750295

COMPLETED Phase 3 57 participants

Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome

Baylor Research Institute

NCT02251431

COMPLETED NA 50 participants

Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes

Geisinger Clinic

NCT03015480

COMPLETED NA 41 participants

Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo

Amy Barton Pai

NCT00915876

COMPLETED 41 participants

Hemodialysis Vascular Access Imaging Study

Renal Research Institute

NCT02374762

COMPLETED Early Phase 1 40 participants

Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease

University of Alabama at Birmingham

NCT01988116

COMPLETED Phase 4 38 participants

Rifaximin Therapy in Chronic Kidney Disease

Jason Stubbs, MD

NCT02342639

COMPLETED NA 34 participants

Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects

Atlanta VA Medical Center

NCT00427037

COMPLETED Early Phase 1 34 participants

Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

University of Colorado, Denver

NCT04600323

COMPLETED NA 33 participants

FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.

FAST BioMedical

NCT01978314

COMPLETED Phase 1 33 participants

Study to Assess PK, Safety and Tolerability in Patients With DM and CKD

DiaMedica Therapeutics

NCT03795389

COMPLETED Phase 3 30 participants

Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease

Kenneth R. Phelps, M.D.

NCT01191762

COMPLETED NA 23 participants

Advanced Glycation End-products, Inflammation and Vascular Health in Chronic Kidney Disease

University of Alabama at Birmingham

NCT01769963

COMPLETED Phase 2 22 participants

Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease

University of Washington

NCT00552409

COMPLETED Phase 2 21 participants

Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease

University of Alabama at Birmingham

NCT02497300

COMPLETED NA 18 participants

Multicultural Healthy Diet in Chronic Kidney Disease

Montefiore Medical Center

NCT05504850

COMPLETED Phase 1 18 participants

A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease

Renibus Therapeutics

NCT04072432

COMPLETED NA 16 participants

Analysis of Calcium Balance in Chronic Kidney Disease

University of Colorado, Denver

NCT00974532

COMPLETED NA 15 participants

The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients

University of Florida

NCT01842087

COMPLETED NA 15 participants

Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease

Geoffrey Block

NCT01341678

COMPLETED NA 14 participants

Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

University of Tennessee

NCT06123195

COMPLETED 14 participants

Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease

University of California, Irvine

NCT00793806

COMPLETED 12 participants

Effects Of Darbepoetin On Vascular Repair Mechanisms In Kidney Disease The DARBEPC Study

University of Michigan

NCT00396123

COMPLETED Phase 1 11 participants

A Trial of Doxycycline in Renal Disease

University of California, San Francisco

NCT02753426

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 17
Phase 3 19
Phase 4 8

Named interventions

Most-linked intervention names on Chronic Kidney Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
20 trials
Empagliflozin Drug
5 trials
Placebo Other
5 trials
placebo Drug
3 trials
Cholecalciferol Drug
2 trials
Finerenone (Kerendia, BAY94-8862) Drug
2 trials
Semaglutide Drug
2 trials
Exercise Training Behavioral
2 trials

US sites by state

Facility locations filed on Chronic Kidney Disease trials. A trial with sites in several states counts in each.

California 31 trials
Florida 26 trials
Colorado 20 trials
Illinois 19 trials
Texas 18 trials
Georgia 18 trials
Arizona 18 trials
Alabama 17 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Kidney Disease page

103 registered trials, 32 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 32 Chronic Kidney Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Bayer sponsors the most Chronic Kidney Disease trials on record, review their full trial history before evaluating a specific study. See Bayer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Kidney Disease condition card totals 103 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.