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ClinicalTrials.gov 32 recruiting now official registry

Chronic Kidney Disease clinical trials

32 of 103 indexed Chronic Kidney Disease trials are currently recruiting.

103 US clinical trials · 32 currently recruiting

Chronic Kidney Disease is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 8 of these trials.

The research picture

Chronic Kidney Disease has 103 registered US clinical trials, 32 of them open to new participants right now, about 31% of the total.

32
recruiting participants now
31%
of trials open to enrollment
27
in Phase 3–4 (later-stage)
8
top sponsor: Bayer
Phase 110Phase 217Phase 319Phase 48

Active & Recent Trials

103 total, page 2 of 3

COMPLETED Phase 3 601 participants

Telemonitoring to Improve Outcomes of Patients With Chronic Kidney Disease (CKD)

Minneapolis Veterans Affairs Medical Center

NCT01446029

COMPLETED NA 580 participants

Is There a Digital Divide in Chronic Kidney Disease (CKD)?

Duke University

NCT03067779

COMPLETED Phase 3 521 participants

Comparing Safety and Immunogenicity of HEPLISAV-B® to Engerix-B® in Chronic Kidney Disease (CKD) Patients

Dynavax Technologies Corporation

NCT00985426

COMPLETED Phase 2 281 participants

The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors

Abbott

NCT00421733

COMPLETED NA 280 participants

Palm Tocotrienols in Chronic Hemodialysis (USA)

Wayne State University

NCT02358967

COMPLETED NA 270 participants

Diabetes CKD Lifestyle Technology Study

NYU Langone Health

NCT02266823

COMPLETED Phase 3 241 participants

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes

Bayer

NCT05901831

COMPLETED Phase 2 227 participants

Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease

Biogen

NCT00811889

COMPLETED Phase 2 210 participants

20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia

Akebia Therapeutics

NCT01906489

COMPLETED Phase 3 200 participants

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

Denver Nephrologists, P.C.

NCT02492620

COMPLETED Phase 3 184 participants

Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis

Takeda

NCT01478971

COMPLETED NA 167 participants

A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease

Denver Nephrologists, P.C.

NCT01475760

COMPLETED Phase 2 154 participants

Study of Phosphate Levels in Patients With Chronic Kidney Disease

Vifor Pharma

NCT00824460

COMPLETED Phase 3 128 participants

Vitamin D and Arterial Function in Patients With Chronic Kidney Disease

University of Colorado, Denver

NCT01384539

COMPLETED Phase 2 125 participants

Metformin in Kidney Disease

VA Office of Research and Development

NCT02252081

COMPLETED 114 participants

DyeVert™ Plus Contrast Reduction System Multicenter Observational Study

Osprey Medical

NCT03715452

COMPLETED Phase 3 106 participants

A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)

Novo Nordisk A/S

NCT04865770

COMPLETED NA 106 participants

Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)

Srinvasan Beddhu

NCT02970123

COMPLETED NA 100 participants

A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making

Massachusetts General Hospital

NCT02698722

COMPLETED Phase 4 92 participants

Trial to Optimize Mineral Outcomes in Dialysis Patients

University of Colorado, Denver

NCT01100723

COMPLETED Phase 2 90 participants

Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia

ZS Pharma

NCT01493024

COMPLETED 90 participants

Endothelial Microparticles: A Novel Marker of Vascular Dysfunction

University of Colorado, Denver

NCT02230202

COMPLETED Phase 2 83 participants

A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease

Prokidney

NCT02836574

COMPLETED Phase 4 66 participants

Phosphate Lowering in CKD Trial

VA Office of Research and Development

NCT02209636

COMPLETED Phase 2 62 participants

Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)

Vanderbilt University

NCT00308971

COMPLETED NA 60 participants

Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency

University of Alabama at Birmingham

NCT02888171

COMPLETED Phase 1 60 participants

A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis

Novartis Pharmaceuticals

NCT00750295

COMPLETED Phase 3 57 participants

Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome

Baylor Research Institute

NCT02251431

COMPLETED NA 50 participants

Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes

Geisinger Clinic

NCT03015480

COMPLETED NA 41 participants

Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo

Amy Barton Pai

NCT00915876

COMPLETED 41 participants

Hemodialysis Vascular Access Imaging Study

Renal Research Institute

NCT02374762

COMPLETED Early Phase 1 40 participants

Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease

University of Alabama at Birmingham

NCT01988116

COMPLETED Phase 4 38 participants

Rifaximin Therapy in Chronic Kidney Disease

Jason Stubbs, MD

NCT02342639

COMPLETED NA 34 participants

Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects

Atlanta VA Medical Center

NCT00427037

COMPLETED Early Phase 1 34 participants

Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

University of Colorado, Denver

NCT04600323

COMPLETED NA 33 participants

FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.

FAST BioMedical

NCT01978314

COMPLETED Phase 1 33 participants

Study to Assess PK, Safety and Tolerability in Patients With DM and CKD

DiaMedica Therapeutics

NCT03795389

COMPLETED Phase 3 30 participants

Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease

Kenneth R. Phelps, M.D.

NCT01191762

COMPLETED NA 23 participants

Advanced Glycation End-products, Inflammation and Vascular Health in Chronic Kidney Disease

University of Alabama at Birmingham

NCT01769963

COMPLETED Phase 2 22 participants

Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease

University of Washington

NCT00552409

COMPLETED Phase 2 21 participants

Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease

University of Alabama at Birmingham

NCT02497300

COMPLETED NA 18 participants

Multicultural Healthy Diet in Chronic Kidney Disease

Montefiore Medical Center

NCT05504850

COMPLETED Phase 1 18 participants

A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease

Renibus Therapeutics

NCT04072432

COMPLETED NA 16 participants

Analysis of Calcium Balance in Chronic Kidney Disease

University of Colorado, Denver

NCT00974532

COMPLETED NA 15 participants

The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients

University of Florida

NCT01842087

COMPLETED NA 15 participants

Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease

Geoffrey Block

NCT01341678

COMPLETED NA 14 participants

Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

University of Tennessee

NCT06123195

COMPLETED 14 participants

Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease

University of California, Irvine

NCT00793806

COMPLETED 12 participants

Effects Of Darbepoetin On Vascular Repair Mechanisms In Kidney Disease The DARBEPC Study

University of Michigan

NCT00396123

COMPLETED Phase 1 11 participants

A Trial of Doxycycline in Renal Disease

University of California, San Francisco

NCT02753426

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 17
Phase 3 19
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Kidney Disease Trial Landscape

103 indexed Chronic Kidney Disease studies · 32 recruiting (31%).

Phase mix: 27 late (III/IV) vs 27 early (I/II).

Top sponsor: Bayer (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Kidney Disease?

PlainTrial tracks 103 US clinical trials for Chronic Kidney Disease, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Kidney Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.