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ClinicalTrials.gov 6 recruiting now full pipeline

Cardiac Disease: full-pipeline trial registry

6 of 25 indexed Cardiac Disease trials are currently recruiting.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 6 currently recruiting · #652 of 28,707 conditions by registered trial count

Cardiac Disease: 25 US clinical trials tracked, 6 recruiting.

Cardiac Disease is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Northwell Health, running 2 of these trials.

Enrollment posture brief

Registry condition cardiac-disease

OPEN 6 | RECR 24% | LATE 3 | EARLY 2 | RANK #652 | SPON 2

Nearest open-share peer: Morbid Obesity (24% recruiting · 25 trials)

Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%Cardiac Disease (this)24%
Open-enrollment share among volume-matched conditions near Cardiac Disease

Cardiac Disease lists 6 open slots (24% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiac Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiac Disease is recruiting below its size-band peers.

    6 of 25 indexed trials (24%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cardiac Disease trials is spread across many organizations.

    Northwell Health accounts for 2 of 25 trials (8%). 21 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiac Disease enrolment sits around 153 participants.

    Median target enrolment is 153 among the 25 trials that report a genuine target (sentinel values excluded). 9 of those (36%) plan for fewer than 100 participants.

  4. Cardiac Disease splits between interventional and observational designs.

    15 interventional and 10 observational studies make up this index (60% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 33

Open and recent trials

25 total, page 1 of 1

RECRUITING 10,500 participants

A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening

Mayo Clinic

NCT06891222

RECRUITING 2,000 participants

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Duke University

NCT05055830

RECRUITING Phase 2 140 participants

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

Northwell Health

NCT07032792

RECRUITING NA 75 participants

Rectus Sheath Block in Cardiac Surgery

Icahn School of Medicine at Mount Sinai

NCT05833048

RECRUITING NA 70 participants

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

University of Colorado, Denver

NCT03204357

RECRUITING 50 participants

Cardiac Performance System Data Collection Study - Minnesota

Sensydia Corporation

NCT06149143

ACTIVE NOT RECRUITING NA 2,500 participants

Repository of Phase Signals for Pulmonary Hypertension Algorithm Development

Analytics For Life

NCT04031989

ACTIVE NOT RECRUITING Phase 3 736 participants

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

Alexion Pharmaceuticals

NCT05746559

ACTIVE NOT RECRUITING NA 250 participants

The Effectiveness of 4D Image Acquisition and Post-processing With Vios Works

Northwell Health

NCT03128268

ACTIVE NOT RECRUITING 75 participants

The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry

Saint Luke's Health System

NCT04828070

ACTIVE NOT RECRUITING 30 participants

Cardiovascular Structure and Function in the Mucopolysaccharidoses

Children's Hospital of Orange County

NCT05063435

COMPLETED 1,012 participants

World Trade Center (WTC) CHEST

Icahn School of Medicine at Mount Sinai

NCT01466218

COMPLETED 597 participants

Retrospective Experience Of CIED Implantation

Elutia

NCT04351269

COMPLETED NA 241 participants

Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)

Vasorum

NCT01600482

COMPLETED NA 240 participants

Prospective Evaluation OF Heartfocus

DESKi

NCT05874128

COMPLETED NA 209 participants

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

University of Alabama at Birmingham

NCT03767517

COMPLETED 207 participants

Dysphagia and VFMI in Cardiac Patients

University of Florida

NCT03768739

COMPLETED Phase 3 153 participants

DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Lantheus Medical Imaging

NCT03571672

COMPLETED 153 participants

Kosmos Trio and Ejection Fraction Pivotal Study

EchoNous

NCT06027164

COMPLETED Phase 3 153 participants

Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:

The Cleveland Clinic

NCT04501861

COMPLETED NA 101 participants

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

Gabi SmartCare

NCT05319236

COMPLETED 84 participants

Triple Antithrombotic Therapy in Cardiac Patients Requiring Revascularization

Methodist Health System

NCT03889574

COMPLETED NA 67 participants

Cardiopulmonary Outpatient Rehabilitation Using Mobile Technology

NYU Langone Health

NCT02671669

COMPLETED NA 56 participants

A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch

The Cleveland Clinic

NCT03986281

COMPLETED Phase 2 32 participants

Lidocaine as an Endotracheal Tube (ETT) Cuff Media

Mayo Clinic

NCT03343080

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 3

Top Sponsors

Northwell Health 2 trials
Mayo Clinic 2 trials
DESKi 1 trials
EchoNous 1 trials
Vasorum 1 trials
Gabi SmartCare 1 trials
Elutia 1 trials

Named interventions

Most-linked intervention names on Cardiac Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Active Intervention Other
1 trials
Movn application (MVN) Behavioral
1 trials
Portable Ultrasound System Device
1 trials
Using HeartFocus software without AI-guidance Device
1 trials
Using HeartFocus software with AI guidance (Novices) Device
1 trials
1.8% lidocaine plus 0.76% sodium bicarbonate Drug
1 trials
DEFINITY Drug
1 trials
Standard Arterial Line Other
1 trials

US sites by state

Facility locations filed on Cardiac Disease trials. A trial with sites in several states counts in each.

New York 11 trials
Ohio 4 trials
North Carolina 4 trials
Minnesota 3 trials
Michigan 3 trials
Georgia 3 trials
Colorado 3 trials
California 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiac Disease page

25 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiac Disease condition card totals 25 registered trials; most-linked intervention Active Intervention; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.