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Cardiac Disease clinical trials
Every US clinical trial registered for Cardiac Disease — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
25 US clinical trials · 6 currently recruiting
The research picture
Cardiac Disease has 25 registered US clinical trials, 6 of them open to new participants right now — about 24% of the total.
- 6
- recruiting participants now
- 24%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Northwell Health
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
Mayo Clinic
NCT06891222
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
Duke University
NCT05055830
Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery
Northwell Health
NCT07032792
Rectus Sheath Block in Cardiac Surgery
Icahn School of Medicine at Mount Sinai
NCT05833048
Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
University of Colorado, Denver
NCT03204357
Cardiac Performance System Data Collection Study - Minnesota
Sensydia Corporation
NCT06149143
Repository of Phase Signals for Pulmonary Hypertension Algorithm Development
Analytics For Life
NCT04031989
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
Alexion Pharmaceuticals
NCT05746559
The Effectiveness of 4D Image Acquisition and Post-processing With Vios Works
Northwell Health
NCT03128268
The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry
Saint Luke's Health System
NCT04828070
Cardiovascular Structure and Function in the Mucopolysaccharidoses
Children's Hospital of Orange County
NCT05063435
World Trade Center (WTC) CHEST
Icahn School of Medicine at Mount Sinai
NCT01466218
Retrospective Experience Of CIED Implantation
Elutia
NCT04351269
Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)
Vasorum
NCT01600482
PROSPECTIVE EVALUATION OF HEARTFOCUS
DESKi
NCT05874128
A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders
University of Alabama at Birmingham
NCT03767517
Dysphagia and VFMI in Cardiac Patients
University of Florida
NCT03768739
DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY
Lantheus Medical Imaging
NCT03571672
Kosmos Trio and Ejection Fraction Pivotal Study
EchoNous
NCT06027164
Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:
The Cleveland Clinic
NCT04501861
Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Gabi SmartCare
NCT05319236
Triple Antithrombotic Therapy in Cardiac Patients Requiring Revascularization
Methodist Health System
NCT03889574
Cardiopulmonary Outpatient Rehabilitation Using Mobile Technology
NYU Langone Health
NCT02671669
A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch
The Cleveland Clinic
NCT03986281
Lidocaine as an Endotracheal Tube (ETT) Cuff Media
Mayo Clinic
NCT03343080
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiac Disease Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Cardiac Disease, and 6 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cardiac Disease shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cardiac Disease is led by Northwell Health with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiac Disease?
PlainTrial tracks 25 US clinical trials for Cardiac Disease, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiac Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.