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NCT03204357 · ClinicalTrials.gov registry record · NA
Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
A NA study of Cardiac Disease and Bleeding Postoperative, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT03204357: Recruiting NA study of Cardiac Disease and Bleeding Postoperative, sponsored by University of Colorado, Denver.
NCT03204357 is a NA study of Cardiac Disease and Bleeding Postoperative that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 70 participants, below the 819-participant average among 24 other Cardiac Disease trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03204357, a NA study of Cardiac Disease and Bleeding Postoperative, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous whole blood versus standard of care expectant management of bleeding during elective cardiac surgery.
Primary Outcome
Blood loss is estimated as a percent of total estimated blood volume in the first 24 hours after cardiac surgery.
Conditions Studied
Interventions
- OTHER Fresh Autologous whole Blood
- OTHER Standard of Care Expectant management of bleeding
Study Locations (1)
Colorado
- University of Colorado Hospital - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2022-01-24 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT03204357 shows while recruiting
NCT03204357 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 819-participant average among 24 other Cardiac Disease trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Cardiac Disease appearing as the primary indexed condition, and to 2 interventions - of which Fresh Autologous whole Blood is the first listed.
NCT03204357 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT03204357 about?
NCT03204357 is a clinical study titled "Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass". Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous wh...
What is the current status of trial NCT03204357?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2022-01-24. Estimated completion is 2026-09.
What conditions does trial NCT03204357 study?
This clinical trial studies the following conditions: Cardiac Disease, Bleeding Postoperative.
What interventions are being tested in trial NCT03204357?
The interventions under investigation include: Fresh Autologous whole Blood (OTHER), Standard of Care Expectant management of bleeding (OTHER).
Who is sponsoring clinical trial NCT03204357?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03204357 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03204357's enrollment target sits among peer trials
70 20th of 24 higher than 5 of 24 other Cardiac Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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