Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Morbid Obesity

Open-data reference.

25 US clinical trials · 6 currently recruiting

Active & Recent Trials

RECRUITING 500 participants

Metabolic Responses to Bariatric Surgery

University of California, Davis

NCT02024542

RECRUITING 300 participants

Gut Microbiota in Metabolic Surgery

Vanderbilt University Medical Center

NCT05000996

RECRUITING NA 262 participants

Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)

Salvador Navarrete

NCT06293703

RECRUITING Early Phase 1 162 participants

Induction of Labor in Morbidly Obese Patients

University of Maryland, Baltimore

NCT06199154

RECRUITING Phase 4 150 participants

Impact GLP-1 Agonists Following Bariatric

University of Missouri-Columbia

NCT06132477

RECRUITING 12 participants

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Columbia University

NCT02602769

ACTIVE NOT RECRUITING NA 38 participants

Activity Level Monitoring Study

Ohio State University

NCT05379088

ACTIVE NOT RECRUITING 10 participants

Appetite Suppression / Hormone Study Control Group

Oregon Weight Loss Surgery

NCT02029677

COMPLETED NA 218 participants

Treatment of Low Metabolic Rate Following Bariatric Surgery

Oregon Weight Loss Surgery

NCT01596907

COMPLETED NA 197 participants

Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity

University of California, Irvine

NCT00247377

COMPLETED 180 participants

Follow-up of Adolescent Bariatric Surgery

Children's Hospital Medical Center, Cincinnati

NCT00776776

COMPLETED Phase 4 141 participants

DPE Technique in Labor Epidural for Morbidly Obese Women

Duke University

NCT03074695

COMPLETED Phase 2 100 participants

Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic

Pinnacle Health System

NCT00508976

COMPLETED 80 participants

Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients

Masimo Corporation

NCT03021551

COMPLETED Phase 1 72 participants

Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients

Wake Forest University Health Sciences

NCT05537883

COMPLETED NA 66 participants

Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women

Eastern Virginia Medical School

NCT04993651

COMPLETED 61 participants

Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery

University of Massachusetts, Worcester

NCT01007955

COMPLETED 60 participants

Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton

San Francisco Veterans Affairs Medical Center

NCT02778490

COMPLETED 60 participants

Glucose Homeostasis Pre and Post Bariatric Surgery

Washington University School of Medicine

NCT00981500

COMPLETED NA 58 participants

Utilization of Very Low Calorie Diet in Obese General Surgery Patients

Christiana Care Health Services

NCT03553849

COMPLETED NA 57 participants

Laparoscopic Adjustable Gastric Banding in Adolescents

Kirk Reichard

NCT01619488

COMPLETED 45 participants

Neurohumoral Control of Intestinal Electrical and Mechanical Activity

University of California, Davis

NCT00852553

COMPLETED NA 37 participants

Laparoscopic Adjustable Gastric Banding as a Treatment for Morbid Obesity in Adolescents

University of Illinois at Chicago

NCT00592202

COMPLETED NA 31 participants

Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates

University of Michigan

NCT00887393

COMPLETED Phase 3 30 participants

Laparoscopic Sleeve Gastrectomy With and Without Omentectomy

North Texas Veterans Healthcare System

NCT00434525

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 1
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Morbid Obesity Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Morbid Obesity, and 6 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Morbid Obesity shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Morbid Obesity is led by Oregon Weight Loss Surgery with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Morbid Obesity?

PlainTrial tracks 25 US clinical trials for Morbid Obesity, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Morbid Obesity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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