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ClinicalTrials.gov 6 recruiting now full pipeline

Morbid Obesity: full-pipeline trial registry

6 of 25 indexed Morbid Obesity trials are currently recruiting.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 6 currently recruiting · #652 of 28,707 conditions by registered trial count

Morbid Obesity: 25 US clinical trials tracked, 6 recruiting.

Morbid Obesity is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Oregon Weight Loss Surgery, running 2 of these trials.

Enrollment posture brief

Registry condition morbid-obesity

OPEN 6 | RECR 24% | LATE 3 | EARLY 3 | RANK #652 | SPON 2

Nearest open-share peer: Cardiac Disease (24% recruiting · 25 trials)

Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%Morbid Obesity (this)24%
Open-enrollment share among volume-matched conditions near Morbid Obesity

Morbid Obesity lists 6 open slots (24% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Morbid Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Morbid Obesity is recruiting below its size-band peers.

    6 of 25 indexed trials (24%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Morbid Obesity trials is spread across many organizations.

    Oregon Weight Loss Surgery accounts for 2 of 25 trials (8%). 23 distinct sponsors appear on at least one study for this condition label.

  3. Most Morbid Obesity trials plan to enrol fewer than 100 people.

    Median target enrolment is 66 among the 25 trials that report a genuine target (sentinel values excluded). 15 of those (60%) plan for fewer than 100 participants.

  4. Morbid Obesity splits between interventional and observational designs.

    16 interventional and 9 observational studies make up this index (64% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 21Phase 31Phase 42

Open and recent trials

25 total, page 1 of 1

RECRUITING 500 participants

Metabolic Responses to Bariatric Surgery

University of California, Davis

NCT02024542

RECRUITING 300 participants

Gut Microbiota in Metabolic Surgery

Vanderbilt University Medical Center

NCT05000996

RECRUITING NA 262 participants

Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)

Salvador Navarrete

NCT06293703

RECRUITING Early Phase 1 162 participants

Induction of Labor in Morbidly Obese Patients

University of Maryland, Baltimore

NCT06199154

RECRUITING Phase 4 150 participants

Impact GLP-1 Agonists Following Bariatric

University of Missouri-Columbia

NCT06132477

RECRUITING 12 participants

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Columbia University

NCT02602769

ACTIVE NOT RECRUITING NA 38 participants

Activity Level Monitoring Study

Ohio State University

NCT05379088

ACTIVE NOT RECRUITING 10 participants

Appetite Suppression / Hormone Study Control Group

Oregon Weight Loss Surgery

NCT02029677

COMPLETED NA 218 participants

Treatment of Low Metabolic Rate Following Bariatric Surgery

Oregon Weight Loss Surgery

NCT01596907

COMPLETED NA 197 participants

Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity

University of California, Irvine

NCT00247377

COMPLETED 180 participants

Follow-up of Adolescent Bariatric Surgery

Children's Hospital Medical Center, Cincinnati

NCT00776776

COMPLETED Phase 4 141 participants

DPE Technique in Labor Epidural for Morbidly Obese Women

Duke University

NCT03074695

COMPLETED Phase 2 100 participants

Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic

Pinnacle Health System

NCT00508976

COMPLETED 80 participants

Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients

Masimo Corporation

NCT03021551

COMPLETED Phase 1 72 participants

Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients

Wake Forest University Health Sciences

NCT05537883

COMPLETED NA 66 participants

Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women

Eastern Virginia Medical School

NCT04993651

COMPLETED 61 participants

Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery

University of Massachusetts, Worcester

NCT01007955

COMPLETED 60 participants

Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton

San Francisco Veterans Affairs Medical Center

NCT02778490

COMPLETED 60 participants

Glucose Homeostasis Pre and Post Bariatric Surgery

Washington University School of Medicine

NCT00981500

COMPLETED NA 58 participants

Utilization of Very Low Calorie Diet in Obese General Surgery Patients

Christiana Care Health Services

NCT03553849

COMPLETED NA 57 participants

Laparoscopic Adjustable Gastric Banding in Adolescents

Kirk Reichard

NCT01619488

COMPLETED 45 participants

Neurohumoral Control of Intestinal Electrical and Mechanical Activity

University of California, Davis

NCT00852553

COMPLETED NA 37 participants

Laparoscopic Adjustable Gastric Banding as a Treatment for Morbid Obesity in Adolescents

University of Illinois at Chicago

NCT00592202

COMPLETED NA 31 participants

Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates

University of Michigan

NCT00887393

COMPLETED Phase 3 30 participants

Laparoscopic Sleeve Gastrectomy With and Without Omentectomy

North Texas Veterans Healthcare System

NCT00434525

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Morbid Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Sleeve gastrectomy Procedure
1 trials
Laparoscopic restrictive procedure Procedure
1 trials
Adjustable Gastric Band Device
1 trials
gastric banding Procedure
1 trials
gastric bypass Procedure
1 trials
cellulose Drug
1 trials
Ephedrine sulfate with caffeine Drug
1 trials
Standard Epidural (EPL) Drug
1 trials

US sites by state

Facility locations filed on Morbid Obesity trials. A trial with sites in several states counts in each.

California 5 trials
Ohio 3 trials
Oregon 2 trials
North Carolina 2 trials
Missouri 2 trials
Delaware 2 trials
Virginia 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Morbid Obesity page

25 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Morbid Obesity condition card totals 25 registered trials; most-linked intervention Sleeve gastrectomy; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.