Mallinckrodt

69 total trials 52 completed

Mallinckrodt sponsors 69 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 52 completed. 34 of these trials are in Phase 3-4 (later-stage) and 31 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Keratitis, with 1 trials.

Trial Pipeline

69 total, page 1 of 2

COMPLETED Phase 4

Impact of Acthar on Everyday Life of Participants With Severe Keratitis

NCT04169061

COMPLETED Phase 2

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

NCT03712280

TERMINATED Phase 4

Safety and Effectiveness of Acthar Gel for Inflammation of the Eye's Uvea (Middle Layer)

NCT03656692

COMPLETED Phase 4

Acthar Gel in Participants With Pulmonary Sarcoidosis

NCT03320070

TERMINATED

Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension

NCT03132428

TERMINATED Phase 2

Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)

NCT03068754

TERMINATED Phase 3

Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

NCT02321319

COMPLETED Phase 4

Acthar Gel for Active Systemic Lupus Erythematosus (SLE)

NCT02953821

COMPLETED Phase 4

Safety and Effectiveness of Acthar Gel in Participants With Rheumatoid Arthritis

NCT02919761

COMPLETED Phase 1

Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects

NCT02966860

COMPLETED Phase 3

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

NCT02770716

TERMINATED Phase 4

Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain

NCT02746263

COMPLETED Phase 4

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

NCT02848729

COMPLETED Phase 4

Reduction in Pain Intensity Following IV or Oral Pain-relieving Products

NCT02678416

COMPLETED

Observational Registry of Acthar Gel for Participants With Multiple Sclerosis Relapse

NCT02633033

TERMINATED Phase 4

Pharmacokinetics (PK) and Safety Study of XARTEMIS® XR in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain

NCT02508935

TERMINATED Phase 2

Topical Raplixa for Surgical Bleeding in Children

NCT02117349

COMPLETED Phase 3

Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation

NCT01993875

COMPLETED Phase 2

A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis

NCT01906658

TERMINATED Phase 1

Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors

NCT02040558

COMPLETED Phase 4

Acthar for the Treatment of Systemic Lupus Erythematosus (SLE) in Patients With a History of Persistently Active Disease

NCT01753401

COMPLETED Phase 3

Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)

NCT01722864

COMPLETED Phase 3

Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain

NCT01743625

COMPLETED Phase 3

A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients

NCT01635101

COMPLETED Phase 3

A Study of Fibrocaps™ in Surgical Bleeding

NCT01527357

COMPLETED Phase 2

Acthar for Treatment of Proteinuria in Diabetic Nephropathy Patients

NCT01601236

COMPLETED

Assessing Relapse in Multiple Sclerosis (ARMS) Questionnaire

NCT01547351

COMPLETED Early Phase 1

Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)

NCT01380535

COMPLETED Phase 3

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

NCT01484652

COMPLETED Phase 3

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

NCT01451385

COMPLETED Phase 4

Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients

NCT01386554

COMPLETED NA

U.S. Study of Fibrocaps in Surgical Hemostasis

NCT01256164

COMPLETED Phase 3

A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin

NCT01143246

COMPLETED Phase 1

Pharmacokinetics, Bioavailability and Safety of PENNSAID® Gel

NCT01202799

COMPLETED Phase 2

Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis

NCT01119898

COMPLETED Phase 3

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

NCT00931632

TERMINATED Phase 1

Pharmacokinetic Assessment of Sodium Sulfide in Subjects With Impaired Renal Function

NCT00879645

COMPLETED Phase 3

Safety and Efficacy of Intravenous Acetaminophen (IV APAP) in Adult Inpatients

NCT00598559

COMPLETED Phase 3

Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients

NCT00598702

COMPLETED Phase 3

Analgesic Efficacy & Safety of Intravenous (IV) Acetaminophen Versus Placebo for the Treatment of Postop Pain

NCT00564486

COMPLETED Phase 3

Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males

NCT00564629

COMPLETED Phase 1

Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients

NCT00493246

COMPLETED Phase 3

Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult Males

NCT00493311

COMPLETED Phase 3

Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery

NCT00399568

COMPLETED Phase 1

Bioequivalence of a Test Troche Formulation of Fentanyl Citrate (400 mcg) Compared to Actiq® 400 mcg, Cephalon, Inc.

NCT01173627

TERMINATED Phase 2

Nitric Oxide in Myocardial Infarction Size

NCT00568061

TERMINATED Phase 2

The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients

NCT00782652

TERMINATED Phase 3

Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease

NCT00282503

COMPLETED Phase 1

Fed Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

NCT00853268

COMPLETED Phase 1

Fasting Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

NCT00853892

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 15
Phase 3 22
Phase 4 12

What the Pipeline for Mallinckrodt Shows

According to the ClinicalTrials.gov registry, Mallinckrodt is linked to 69 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 52 are already marked complete, representing roughly 75% of the total.

The phase mix for Mallinckrodt reports 34 late-stage studies (Phase 3 and Phase 4 combined) and 31 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Mallinckrodt is Keratitis with 1 linked trial, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.