Mallinckrodt

Closed portfolio snapshot

According to ClinicalTrials.gov-derived indexes, Mallinckrodt sits in the top decile of US sponsors by registered trial count (#307 of 15,742 sponsors by registered trial count).

69 total trials none currently recruiting 52 completed top decile by trial count

Mallinckrodt: 69 sponsored US clinical trials, none currently recruiting.

Mallinckrodt sponsors 69 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 52 completed. 34 of these trials are in Phase 3-4 (later-stage) and 31 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Keratitis, with 1 trials.

Top-decile sponsor footprint

Mallinckrodt ranks in the top decile of sponsors by registered trial count (#307 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 28/100

52 of 69 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

69 total, page 1 of 2

COMPLETED Phase 4

Impact of Acthar on Everyday Life of Participants With Severe Keratitis

NCT04169061

COMPLETED Phase 2

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

NCT03712280

TERMINATED Phase 4

Safety and Effectiveness of Acthar Gel for Inflammation of the Eye's Uvea (Middle Layer)

NCT03656692

COMPLETED Phase 4

Acthar Gel in Participants With Pulmonary Sarcoidosis

NCT03320070

TERMINATED

Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension

NCT03132428

TERMINATED Phase 2

Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)

NCT03068754

TERMINATED Phase 3

Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

NCT02321319

COMPLETED Phase 4

Acthar Gel for Active Systemic Lupus Erythematosus (SLE)

NCT02953821

COMPLETED Phase 4

Safety and Effectiveness of Acthar Gel in Participants With Rheumatoid Arthritis

NCT02919761

COMPLETED Phase 1

Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects

NCT02966860

COMPLETED Phase 3

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

NCT02770716

TERMINATED Phase 4

Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain

NCT02746263

COMPLETED Phase 4

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

NCT02848729

COMPLETED Phase 4

Reduction in Pain Intensity Following IV or Oral Pain-relieving Products

NCT02678416

COMPLETED

Observational Registry of Acthar Gel for Participants With Multiple Sclerosis Relapse

NCT02633033

TERMINATED Phase 4

Pharmacokinetics (PK) and Safety Study of XARTEMIS® XR in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain

NCT02508935

TERMINATED Phase 2

Topical Raplixa for Surgical Bleeding in Children

NCT02117349

COMPLETED Phase 3

Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation

NCT01993875

COMPLETED Phase 2

A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis

NCT01906658

TERMINATED Phase 1

Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors

NCT02040558

COMPLETED Phase 4

Acthar for the Treatment of Systemic Lupus Erythematosus (SLE) in Patients With a History of Persistently Active Disease

NCT01753401

COMPLETED Phase 3

Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)

NCT01722864

COMPLETED Phase 3

Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain

NCT01743625

COMPLETED Phase 3

A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients

NCT01635101

COMPLETED Phase 3

A Study of Fibrocaps™ in Surgical Bleeding

NCT01527357

COMPLETED Phase 2

Acthar for Treatment of Proteinuria in Diabetic Nephropathy Patients

NCT01601236

COMPLETED

Assessing Relapse in Multiple Sclerosis (ARMS) Questionnaire

NCT01547351

COMPLETED Early Phase 1

Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)

NCT01380535

COMPLETED Phase 3

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

NCT01484652

COMPLETED Phase 3

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

NCT01451385

COMPLETED Phase 4

Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients

NCT01386554

COMPLETED NA

U.S. Study of Fibrocaps in Surgical Hemostasis

NCT01256164

COMPLETED Phase 3

A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin

NCT01143246

COMPLETED Phase 1

Pharmacokinetics, Bioavailability and Safety of PENNSAID® Gel

NCT01202799

COMPLETED Phase 2

Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis

NCT01119898

COMPLETED Phase 3

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

NCT00931632

TERMINATED Phase 1

Pharmacokinetic Assessment of Sodium Sulfide in Subjects With Impaired Renal Function

NCT00879645

COMPLETED Phase 3

Safety and Efficacy of Intravenous Acetaminophen (IV APAP) in Adult Inpatients

NCT00598559

COMPLETED Phase 3

Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients

NCT00598702

COMPLETED Phase 3

Analgesic Efficacy & Safety of Intravenous (IV) Acetaminophen Versus Placebo for the Treatment of Postop Pain

NCT00564486

COMPLETED Phase 3

Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males

NCT00564629

COMPLETED Phase 1

Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients

NCT00493246

COMPLETED Phase 3

Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult Males

NCT00493311

COMPLETED Phase 3

Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery

NCT00399568

COMPLETED Phase 1

Bioequivalence of a Test Troche Formulation of Fentanyl Citrate (400 mcg) Compared to Actiq® 400 mcg, Cephalon, Inc.

NCT01173627

TERMINATED Phase 2

Nitric Oxide in Myocardial Infarction Size

NCT00568061

TERMINATED Phase 2

The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients

NCT00782652

TERMINATED Phase 3

Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease

NCT00282503

COMPLETED Phase 1

Fed Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

NCT00853268

COMPLETED Phase 1

Fasting Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

NCT00853892

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 15
Phase 3 22
Phase 4 12

How the Mallinckrodt archive is shaped

69 indexed studies, none listed as recruiting (0% open); 52 completed (75%).

Phase mix: 34 late (III/IV) vs 31 early (I/II) (balanced across stages).

Top condition: Keratitis (1 trial), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Mallinckrodt: archived-pipeline peers nationwide

Peers matched on 69 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Mallinckrodt sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080 0%5%10%15%20%25% Total trials Recruiting share MallinckrodtProvidence Health & ServicesTexas Tech UniversityUniversity of Colorado, BoulderProcter and Gamble10xBio22nd Century Group23andMe3-C Institute for Social Development
Mallinckrodt sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Mallinckrodt sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 69 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Mallinckrodt page

69 registered trials is a research-attention snapshot, not an endorsement of Mallinckrodt or any single study.

  • None of Mallinckrodt's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Keratitis is the condition Mallinckrodt studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Keratitis trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Mallinckrodt pipeline card: 69 registered trials from official public datasets.Report a data error.