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ClinicalTrials.gov 22 recruiting now early-phase tilt

Breast Cancer Female: early-phase trial registry

22 of 47 indexed Breast Cancer Female trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #307 of 28,707 conditions by registered trial count.

47 US clinical trials · 22 currently recruiting · #307 of 28,707 conditions by registered trial count

Breast Cancer Female: 47 US clinical trials tracked, 22 recruiting.

Breast Cancer Female is the subject of 47 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is Dana-Farber Cancer Institute, running 3 of these trials.

Enrollment posture brief

Registry condition breast-cancer-female

OPEN 22 | RECR 47% | LATE 1 | EARLY 14 | RANK #307 | SPON 3

Nearest open-share peer: Myelofibrosis (47% recruiting · 62 trials)

Mesothelioma57.4%Osteosarcoma57.4%Breast Cancer Female (this)47%Adolescent Behavior38.3%Alcohol Abuse21.3%
Open-enrollment share among volume-matched conditions near Breast Cancer Female

Breast Cancer Female lists 22 open slots (47% of 47 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer Female on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer Female is recruiting above its size-band peers.

    22 of 47 indexed trials (46.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer Female trials is spread across many organizations.

    Dana-Farber Cancer Institute accounts for 3 of 47 trials (6.4%). 41 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Cancer Female enrolment sits around 100 participants.

    Median target enrolment is 100 among the 47 trials that report a genuine target (sentinel values excluded). 23 of those (48.9%) plan for fewer than 100 participants.

  4. Breast Cancer Female research is mostly interventional.

    37 interventional and 10 observational studies make up this index (78.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 210Phase 31

Open and recent trials

47 total, page 1 of 1

RECRUITING 20,000 participants

UCF MammoChat: Image Repository

University of Central Florida

NCT07214883

RECRUITING NA 1,500 participants

Biennial CEM in Women With a Personal History of Breast Cancer

Wendie Berg

NCT06105749

RECRUITING NA 1,400 participants

Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)

Breast Cancer Trials, Australia and New Zealand

NCT06445738

RECRUITING 900 participants

Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)

Memorial Sloan Kettering Cancer Center

NCT05561842

RECRUITING Phase 2 452 participants

The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project

University of Arizona

NCT05676255

RECRUITING Phase 3 354 participants

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

University of Virginia

NCT06507618

RECRUITING NA 320 participants

Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women

Cedars-Sinai Medical Center

NCT05298605

RECRUITING NA 270 participants

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

Dana-Farber Cancer Institute

NCT05535192

RECRUITING Phase 2 200 participants

Microbiome and Association With Implant Infections

University of California, San Francisco

NCT05020574

RECRUITING Phase 2 185 participants

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Baylor Breast Care Center

NCT05020860

RECRUITING 160 participants

GammaPod Registry and Quality of Life Nomogram

University of Maryland, Baltimore

NCT03562273

RECRUITING 150 participants

Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI

University of Rochester

NCT03137095

RECRUITING NA 75 participants

Breast Cancer Resiliency Through Exercise Program (B-REP)

University of Michigan Rogel Cancer Center

NCT06100263

RECRUITING Phase 2 72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Dana-Farber Cancer Institute

NCT06439693

RECRUITING NA 60 participants

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

The University of Texas Medical Branch, Galveston

NCT06395506

RECRUITING Phase 2 58 participants

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

Sarah Sammons, MD

NCT06176261

RECRUITING NA 50 participants

Cognitive Rehabilitation Following Breast Cancer Treatment

University of Missouri-Columbia

NCT06545045

RECRUITING NA 46 participants

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

Dana-Farber Cancer Institute

NCT06322888

RECRUITING NA 40 participants

Time Restricted Eating During Chemotherapy for Breast Cancer

University of Illinois at Chicago

NCT05259410

RECRUITING NA 30 participants

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

NCT06115486

RECRUITING NA 19 participants

Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors

University of Utah

NCT07120100

RECRUITING NA 18 participants

Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management

University of Kansas Medical Center

NCT07242118

ACTIVE NOT RECRUITING NA 1,647 participants

Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania

Wendie Berg

NCT04085510

ACTIVE NOT RECRUITING NA 750 participants

Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information in Women

University of Colorado, Denver

NCT06441474

ACTIVE NOT RECRUITING 575 participants

Assessment of Breast Cancer Patients Satisfaction and Health Related Quality of Life Outcomes

Henry Ford Health System

NCT03333122

ACTIVE NOT RECRUITING NA 340 participants

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Wake Forest University Health Sciences

NCT06216574

ACTIVE NOT RECRUITING NA 204 participants

Robotic vs. Open NSM for Early Stage Breast Cancer

Intuitive Surgical

NCT05720039

ACTIVE NOT RECRUITING NA 139 participants

Accelerated Partial Breast Irradiation Study

Sentara Norfolk General Hospital

NCT03437395

ACTIVE NOT RECRUITING Phase 2 119 participants

Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03384914

ACTIVE NOT RECRUITING 100 participants

Diet, Hepcidin, and Chemotherapy RDI

George Washington University

NCT06483997

ACTIVE NOT RECRUITING 94 participants

IORT-Breast at Medical Center Navicent Health

Wake Forest University Health Sciences

NCT04595435

ACTIVE NOT RECRUITING Phase 2 84 participants

Pre-Operative Window of Adjuvant Endocrine Therapy to Inform RT Decisions in Older Women With Early-Stage Breast Cancer

Shayna Showalter, MD

NCT04272801

ACTIVE NOT RECRUITING Phase 1 78 participants

ZAP-IT: ZN-c3 + Carboplatin + Pembrolizumab in mTNBC

Filipa Lynce, MD

NCT06351332

ACTIVE NOT RECRUITING NA 60 participants

Ultrahypofractionation and Normal Tissue Toxicity

Massachusetts General Hospital

NCT05912231

ACTIVE NOT RECRUITING Early Phase 1 31 participants

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03387553

ACTIVE NOT RECRUITING Phase 2 28 participants

A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)

Adrienne G. Waks

NCT06100874

ACTIVE NOT RECRUITING NA 23 participants

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Case Comprehensive Cancer Center

NCT06336538

COMPLETED 525 participants

A Post-Market Clinical Trial to Evaluate the Performance and Operation of the Brevera Breast Biopsy System

Hologic

NCT03300206

COMPLETED NA 310 participants

Using Behavioral Economics to Achieve Improved Healthy Behavior Outcomes in Breast Cancer Survivors

Texas Tech University Health Sciences Center

NCT02938780

COMPLETED Phase 2 134 participants

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Washington University School of Medicine

NCT03084536

COMPLETED 110 participants

Stress Reactivity Among African American Breast Cancer Survivors

Medical University of South Carolina

NCT03881085

COMPLETED Phase 2 61 participants

Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer

University of Texas Southwestern Medical Center

NCT03747042

COMPLETED Early Phase 1 36 participants

A Study to Evaluate Changes in Human Breast Cancer Tissue Following Short-Term Use of Darolutamide

Translational Research in Oncology

NCT03004534

COMPLETED NA 17 participants

Living Well After Breast Surgery

University of Texas at Austin

NCT03834532

COMPLETED 16 participants

Effects of Aromatase Inhibitor Therapy on Muscle Function

Tarah J Ballinger, MD

NCT03581552

COMPLETED Early Phase 1 12 participants

Streaming Web-based Exercise At Home: A Pilot Study

Celina Shirazipour

NCT04282967

COMPLETED NA 12 participants

REJOIN Trial for Older Breast Cancer Survivors

Wake Forest University Health Sciences

NCT03955627

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 10
Phase 3 1

Named interventions

Most-linked intervention names on Breast Cancer Female records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Paclitaxel Drug
2 trials
Carboplatin Drug
2 trials
Trastuzumab Drug
2 trials
Relieving Joint Pain and Improving AI Adherence in Older Breast Cancer Survivors (REJOIN) Behavioral
1 trials
nutrition physical activity text message Other
1 trials
placebo text message Other
1 trials
Breast Biopsy Device
1 trials
Educational website Other
1 trials

US sites by state

Facility locations filed on Breast Cancer Female trials. A trial with sites in several states counts in each.

Texas 9 trials
Massachusetts 7 trials
Florida 7 trials
California 7 trials
Pennsylvania 6 trials
New York 5 trials
Missouri 5 trials
Virginia 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Breast Cancer Female page

47 registered trials, 22 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer Female condition card totals 47 registered trials; most-linked intervention Paclitaxel; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.