Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Alcohol Abuse

Open-data reference.

47 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING NA 744 participants

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

Stanford University

NCT05619185

RECRUITING 300 participants

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

University of Colorado, Denver

NCT02299921

RECRUITING NA 250 participants

Personalized Feedback Intervention for Latinx Drinkers With Anxiety

University of Houston

NCT05246202

RECRUITING NA 200 participants

Virtual Incentive Treatment for Alcohol

Washington State University

NCT06265506

RECRUITING NA 186 participants

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

Brainsway

NCT07216872

RECRUITING NA 100 participants

Adaptation and Evaluation of Bright Horizons

Johns Hopkins Bloomberg School of Public Health

NCT05743699

RECRUITING Phase 2 80 participants

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

University of Iowa

NCT06405607

RECRUITING NA 50 participants

Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety

Michael J. Zvolensky, Ph.D.

NCT05288699

RECRUITING NA 50 participants

A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking

University of Houston

NCT06416059

RECRUITING NA 40 participants

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

VA Palo Alto Health Care System

NCT06415721

ACTIVE NOT RECRUITING NA 525 participants

Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

University of Memphis

NCT04776278

ACTIVE NOT RECRUITING NA 504 participants

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

Kaiser Permanente

NCT01621711

COMPLETED NA 13,680 participants

Screening and Management of Unhealthy Alcohol Use in Primary Care

Virginia Commonwealth University

NCT04248023

COMPLETED NA 7,379 participants

A Community-Based Strategy for Preventing Underage Drinking

Oregon Research Institute

NCT02448134

COMPLETED NA 1,268 participants

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

University of New Hampshire

NCT03488927

COMPLETED NA 1,228 participants

Adolescent Family-Based Alcohol Prevention

Pacific Institute for Research and Evaluation

NCT00858065

COMPLETED NA 750 participants

Health Explorer - Optimizing Alcohol Brief Interventions

University of Michigan

NCT01370226

COMPLETED NA 686 participants

Project Health Link: Connecting Patients With Services

University of Michigan

NCT00234221

COMPLETED NA 591 participants

Using Counter Attitudinal Advocacy to Change Drinking Behavior

Brown University

NCT04042909

COMPLETED NA 400 participants

Improving Health Behaviors Through Telephone Linked Care

American Academy of Family Physicians

NCT00314197

COMPLETED NA 400 participants

Motivational Incentives for Alcohol Abstinence in American Indian and Native Alaskan Adults

Washington State University

NCT02174315

COMPLETED NA 393 participants

Improving Brief Alcohol Interventions With a Behavioral Economic Supplement

University of Memphis

NCT02834949

COMPLETED NA 392 participants

Mindfulness for Alcohol Abusing Offenders

The Mind Research Network

NCT03883646

COMPLETED NA 312 participants

Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse

RAND

NCT02073825

COMPLETED NA 310 participants

Contingency Management Treatment Duration

UConn Health

NCT00732342

COMPLETED NA 239 participants

CARES: A Mobile Health Program for Alcohol Risk Reduction

The Miriam Hospital

NCT03927482

COMPLETED Phase 2 168 participants

Therapeutic Substance Abuse Treatment in Pregnancy - 1

Yale University

NCT00227903

COMPLETED NA 164 participants

Adaptive Interventions for Problem Drinkers

Northwell Health

NCT02511808

COMPLETED NA 150 participants

Facilitating Aftercare for Alcohol Detox Patients

State University of New York at Buffalo

NCT00513708

COMPLETED NA 123 participants

Contingency Management of Alcohol Abuse in the Severely Mentally ILL

University of Washington

NCT01567943

COMPLETED Phase 1 121 participants

Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use

Boston Children's Hospital

NCT00907309

COMPLETED NA 120 participants

Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial

University of Washington

NCT00619255

COMPLETED Phase 1 104 participants

Family Check-Up for Adolescents and Siblings

Brown University

NCT00925340

COMPLETED Phase 2 103 participants

Mifepristone Treatment of Alcohol Use Disorder

The Scripps Research Institute

NCT02179749

COMPLETED Phase 4 90 participants

Naltrexone Treatment of Alcohol Abuse in Schizophrenia

State University of New York - Upstate Medical University

NCT00145847

COMPLETED Phase 2 90 participants

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00246415

COMPLETED NA 89 participants

Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking

Northwell Health

NCT00665249

COMPLETED Phase 3 75 participants

Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

University of Texas Southwestern Medical Center

NCT02918370

COMPLETED Phase 1 64 participants

Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies

Kent State University

NCT04286867

COMPLETED NA 48 participants

Study of Mobile Phone Delivered Intervention to Reduce Alcohol Consumption

University of Southern California

NCT02158949

COMPLETED NA 46 participants

Effects of Levetiracetam (Keppra) on Alcohol Consumption

University of California, San Francis

NCT01168687

COMPLETED NA 40 participants

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

UConn Health

NCT00802321

COMPLETED Phase 4 40 participants

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

UConn Health

NCT00595556

COMPLETED Phase 2 38 participants

Antioxidant Replacement Therapy in Patients With Alcohol Abuse

University of Colorado, Denver

NCT00936000

COMPLETED NA 35 participants

EMPOWER AUD Pivotal Trial

Theranova, L.L.C.

NCT05948605

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED NA 9 participants

Genetic and Neural Factors in Alcohol-Related Cognition

Virginia Commonwealth University

NCT03725345

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 5
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alcohol Abuse Trial Landscape

ClinicalTrials.gov lists 47 US studies indexed under Alcohol Abuse, and 10 of those are currently open to recruitment — roughly 21% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Alcohol Abuse shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Alcohol Abuse is led by Northwell Health with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 47 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alcohol Abuse?

PlainTrial tracks 47 US clinical trials for Alcohol Abuse, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alcohol Abuse?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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