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ClinicalTrials.gov 10 recruiting now early-phase tilt

Alcohol Abuse: early-phase trial registry

10 of 47 indexed Alcohol Abuse trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #307 of 28,707 conditions by registered trial count.

47 US clinical trials · 10 currently recruiting · #307 of 28,707 conditions by registered trial count

Alcohol Abuse: 47 US clinical trials tracked, 10 recruiting.

Alcohol Abuse is the subject of 47 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Northwell Health, running 3 of these trials.

Enrollment posture brief

Registry condition alcohol-abuse

OPEN 10 | RECR 21% | LATE 3 | EARLY 9 | RANK #307 | SPON 3

Nearest open-share peer: Osteoarthritis (21% recruiting · 136 trials)

Mesothelioma57.4%Osteosarcoma57.4%Breast Cancer Female46.8%Adolescent Behavior38.3%Alcohol Abuse (this)21%
Open-enrollment share among volume-matched conditions near Alcohol Abuse

Alcohol Abuse lists 10 open slots (21% of 47 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Alcohol Abuse on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Alcohol Abuse is recruiting below its size-band peers.

    10 of 47 indexed trials (21.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Alcohol Abuse trials is spread across many organizations.

    Northwell Health accounts for 3 of 47 trials (6.4%). 35 distinct sponsors appear on at least one study for this condition label.

  3. Typical Alcohol Abuse enrolment sits around 150 participants.

    Median target enrolment is 150 among the 47 trials that report a genuine target (sentinel values excluded). 17 of those (36.2%) plan for fewer than 100 participants.

  4. Alcohol Abuse research is mostly interventional.

    46 interventional and 1 observational studies make up this index (97.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 25Phase 31Phase 42

Open and recent trials

47 total, page 1 of 1

RECRUITING NA 744 participants

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

Stanford University

NCT05619185

RECRUITING 300 participants

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

University of Colorado, Denver

NCT02299921

RECRUITING NA 250 participants

Personalized Feedback Intervention for Latinx Drinkers With Anxiety

University of Houston

NCT05246202

RECRUITING NA 200 participants

Virtual Incentive Treatment for Alcohol

Washington State University

NCT06265506

RECRUITING NA 186 participants

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

Brainsway

NCT07216872

RECRUITING NA 100 participants

Adaptation and Evaluation of Bright Horizons

Johns Hopkins Bloomberg School of Public Health

NCT05743699

RECRUITING Phase 2 80 participants

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

University of Iowa

NCT06405607

RECRUITING NA 50 participants

Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety

Michael J. Zvolensky, Ph.D.

NCT05288699

RECRUITING NA 50 participants

A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking

University of Houston

NCT06416059

RECRUITING NA 40 participants

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

VA Palo Alto Health Care System

NCT06415721

ACTIVE NOT RECRUITING NA 525 participants

Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

University of Memphis

NCT04776278

ACTIVE NOT RECRUITING NA 504 participants

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

Kaiser Permanente

NCT01621711

COMPLETED NA 13,680 participants

Screening and Management of Unhealthy Alcohol Use in Primary Care

Virginia Commonwealth University

NCT04248023

COMPLETED NA 7,379 participants

A Community-Based Strategy for Preventing Underage Drinking

Oregon Research Institute

NCT02448134

COMPLETED NA 1,268 participants

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

University of New Hampshire

NCT03488927

COMPLETED NA 1,228 participants

Adolescent Family-Based Alcohol Prevention

Pacific Institute for Research and Evaluation

NCT00858065

COMPLETED NA 750 participants

Health Explorer - Optimizing Alcohol Brief Interventions

University of Michigan

NCT01370226

COMPLETED NA 686 participants

Project Health Link: Connecting Patients With Services

University of Michigan

NCT00234221

COMPLETED NA 591 participants

Using Counter Attitudinal Advocacy to Change Drinking Behavior

Brown University

NCT04042909

COMPLETED NA 400 participants

Improving Health Behaviors Through Telephone Linked Care

American Academy of Family Physicians

NCT00314197

COMPLETED NA 400 participants

Motivational Incentives for Alcohol Abstinence in American Indian and Native Alaskan Adults

Washington State University

NCT02174315

COMPLETED NA 393 participants

Improving Brief Alcohol Interventions With a Behavioral Economic Supplement

University of Memphis

NCT02834949

COMPLETED NA 392 participants

Mindfulness for Alcohol Abusing Offenders

The Mind Research Network

NCT03883646

COMPLETED NA 312 participants

Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse

RAND

NCT02073825

COMPLETED NA 310 participants

Contingency Management Treatment Duration

UConn Health

NCT00732342

COMPLETED NA 239 participants

CARES: A Mobile Health Program for Alcohol Risk Reduction

The Miriam Hospital

NCT03927482

COMPLETED Phase 2 168 participants

Therapeutic Substance Abuse Treatment in Pregnancy - 1

Yale University

NCT00227903

COMPLETED NA 164 participants

Adaptive Interventions for Problem Drinkers

Northwell Health

NCT02511808

COMPLETED NA 150 participants

Facilitating Aftercare for Alcohol Detox Patients

State University of New York at Buffalo

NCT00513708

COMPLETED NA 123 participants

Contingency Management of Alcohol Abuse in the Severely Mentally ILL

University of Washington

NCT01567943

COMPLETED Phase 1 121 participants

Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use

Boston Children's Hospital

NCT00907309

COMPLETED NA 120 participants

Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial

University of Washington

NCT00619255

COMPLETED Phase 1 104 participants

Family Check-Up for Adolescents and Siblings

Brown University

NCT00925340

COMPLETED Phase 2 103 participants

Mifepristone Treatment of Alcohol Use Disorder

The Scripps Research Institute

NCT02179749

COMPLETED Phase 4 90 participants

Naltrexone Treatment of Alcohol Abuse in Schizophrenia

State University of New York - Upstate Medical University

NCT00145847

COMPLETED Phase 2 90 participants

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00246415

COMPLETED NA 89 participants

Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking

Northwell Health

NCT00665249

COMPLETED Phase 3 75 participants

Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

University of Texas Southwestern Medical Center

NCT02918370

COMPLETED Phase 1 64 participants

Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies

Kent State University

NCT04286867

COMPLETED NA 48 participants

Study of Mobile Phone Delivered Intervention to Reduce Alcohol Consumption

University of Southern California

NCT02158949

COMPLETED NA 46 participants

Effects of Levetiracetam (Keppra) on Alcohol Consumption

University of California, San Francisco

NCT01168687

COMPLETED NA 40 participants

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

UConn Health

NCT00802321

COMPLETED Phase 4 40 participants

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

UConn Health

NCT00595556

COMPLETED Phase 2 38 participants

Antioxidant Replacement Therapy in Patients With Alcohol Abuse

University of Colorado, Denver

NCT00936000

COMPLETED NA 35 participants

EMPOWER AUD Pivotal Trial

Theranova, L.L.C.

NCT05948605

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED NA 9 participants

Genetic and Neural Factors in Alcohol-Related Cognition

Virginia Commonwealth University

NCT03725345

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 5
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Alcohol Abuse records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Contingency Management Behavioral
4 trials
Placebo Drug
4 trials
Brief Advice Behavioral
3 trials
Motivational Interviewing Behavioral
2 trials
Standardized behavioral therapy Behavioral
1 trials
Mifepristone 1200 mg daily Drug
1 trials
Protandim Dietary supplement
1 trials
zonisamide Drug
1 trials

US sites by state

Facility locations filed on Alcohol Abuse trials. A trial with sites in several states counts in each.

California 10 trials
New York 7 trials
Texas 5 trials
Connecticut 5 trials
Washington 4 trials
Rhode Island 3 trials
Virginia 2 trials
Tennessee 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Alcohol Abuse page

47 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Abuse condition card totals 47 registered trials; most-linked intervention Contingency Management; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.