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NCT03137095 · ClinicalTrials.gov registry record
Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI
A clinical trial of Breast Cancer Female and Cancer-related Cognitive Difficulties, sponsored by University of Rochester.
- Recruiting
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT03137095: Recruiting study of Breast Cancer Female and Cancer-related Cognitive Difficulties, sponsored by University of Rochester.
NCT03137095 is a study of Breast Cancer Female and Cancer-related Cognitive Difficulties that is actively recruiting participants, run by University of Rochester. The registered enrollment target is 150 participants, below the 689-participant average among 46 other Breast Cancer Female trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03137095, a study of Breast Cancer Female and Cancer-related Cognitive Difficulties, is actively recruiting participants, sponsored by University of Rochester.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prevalence of cognitive difficulties in cancer patients receiving chemotherapy compared to the general population as well as what biological mechanisms may play a role in the development of these difficulties. Patients will be asked to complete six assessments over the course of approximately 5 months. Assessments 1,3, 4.5 and 5 include computerized and paper and pencil cognitive testing as well as blood draws. Assessments 2 and 4 only involve the collection of a blood sample. An optional sub study is offered after Assessment 1. It involves a research brain MRI at Assessment 4.5 and cognitive testing and another research brain MRI at Assessment 6.
Primary Outcome
Change scores from baseline will be computed for each cognitive measure as well as each mechanistic marker
Conditions Studied
Interventions
- OTHER Cognitive testing
- OTHER Research Brain MRI
Study Locations (1)
New York
- University of Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2017-02-20 |
| Est. Completion | 2026-07-31 |
What NCT03137095 shows while recruiting
NCT03137095 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 689-participant average among 46 other Breast Cancer Female trials with a reported enrollment target (78% lower).
The record links to 2 conditions, with Breast Cancer Female appearing as the primary indexed condition, and to 2 interventions - of which Cognitive testing is the first listed.
NCT03137095 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03137095 about?
NCT03137095 is a clinical study titled "Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI". Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prevalence of cognitive difficulties in cancer patients receiving chemotherapy compared to the general population as well as...
What is the current status of trial NCT03137095?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2017-02-20. Estimated completion is 2026-07-31.
What conditions does trial NCT03137095 study?
This clinical trial studies the following conditions: Breast Cancer Female, Cancer-related Cognitive Difficulties.
What interventions are being tested in trial NCT03137095?
The interventions under investigation include: Cognitive testing (OTHER), Research Brain MRI (OTHER).
Who is sponsoring clinical trial NCT03137095?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03137095 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer Female
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03137095's enrollment target sits among peer trials
150 19th of 46 higher than 28 of 46 other Breast Cancer Female trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer Female trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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