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NCT07242118 · ClinicalTrials.gov registry record · NA

Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management

A NA study of Breast Cancer Female, sponsored by University of Kansas Medical Center.

Recruiting
Registry status
NA
Development phase
18
Enrollment target
2
Study locations

NCT07242118: Recruiting NA study of Breast Cancer Female, sponsored by University of Kansas Medical Center.

NCT07242118 is a NA study of Breast Cancer Female that is actively recruiting participants, run by University of Kansas Medical Center. The registered enrollment target is 18 participants, below the 692-participant average among 46 other Breast Cancer Female trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07242118, a NA study of Breast Cancer Female, is actively recruiting participants, sponsored by University of Kansas Medical Center.

RECRUITING
Registry status
NA
Development phase
18 participants
Enrollment target
2
Study locations

Study Summary

This phase II study evaluates SABR as non-operative treatment for women aged 65+ with ER-positive, HER2-negative breast cancer ≤5 cm and no lymph node involvement. Eligible patients, including those previously on endocrine therapy, receive 5 SABR treatments, followed by monitoring of quality of life and assessment of treatment-related toxicity.

Primary Outcome

To estimate the change in the score from baseline to 1-month post-SABR on the BREAST-Q: Physical Well-Being Chest Module in older women receiving non-operative management with SABR for localized breast cancer. Conversion Table will be used to convert the raw scale summed score into a score from 0 (worst) to 100 (best). Higher scores reflect a better outcome.

Conditions Studied

Interventions

  • RADIATION SABR

Study Locations (2)

Kansas

  • University of Kansas Medical Center - Kansas City
  • University of Kansas Medical Center - Kansas City

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2025-11-04
Est. Completion 2027-10
Phase NA
University of Kansas Medical Center

408 total trials

What NCT07242118 shows while recruiting

NCT07242118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 692-participant average among 46 other Breast Cancer Female trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Breast Cancer Female appearing as the primary indexed condition, and to 1 intervention - of which SABR is the first listed.

NCT07242118 reports a single indexed study location in Kansas.

Frequently Asked Questions

What is clinical trial NCT07242118 about?

NCT07242118 is a clinical study titled "Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management". This phase II study evaluates SABR as non-operative treatment for women aged 65+ with ER-positive, HER2-negative breast cancer ≤5 cm and no lymph node involvement. Eligible patients, including those previously on endocrine therapy, receive 5 SABR treatments, followed by monitoring of quality of life...

What is the current status of trial NCT07242118?

This trial is currently recruiting. It is a NA study. The enrollment target is 18 participants. The study started on 2025-11-04. Estimated completion is 2027-10.

What conditions does trial NCT07242118 study?

This clinical trial studies the following conditions: Breast Cancer Female.

What interventions are being tested in trial NCT07242118?

The interventions under investigation include: SABR (RADIATION).

Who is sponsoring clinical trial NCT07242118?

This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07242118 being conducted?

This trial has 2 study locations across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer Female

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07242118's enrollment target sits among peer trials

18 43rd of 46 higher than 4 of 46 other Breast Cancer Female trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer Female trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07242118, the US trial registry maintained by the National Library of Medicine. NCT07242118 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.