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ClinicalTrials.gov 34 recruiting now early-phase tilt

Brain Tumor: early-phase trial registry

34 of 71 indexed Brain Tumor trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #197 of 28,707 conditions by registered trial count.

71 US clinical trials · 34 currently recruiting · #197 of 28,707 conditions by registered trial count

Brain Tumor: 71 US clinical trials tracked, 34 recruiting.

Brain Tumor is the subject of 71 registered US clinical trials on ClinicalTrials.gov, 34 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 6 of these trials.

Enrollment posture brief

Registry condition brain-tumor

OPEN 34 | RECR 48% | LATE 2 | EARLY 28 | RANK #197 | SPON 6

Nearest open-share peer: Aging (48% recruiting · 263 trials)

Brain Tumor (this)48%Crohn Disease47.2%Chronic Low Back Pain41.7%Hodgkin Lymphoma38.9%HIV-1-infection33.3%
Open-enrollment share among volume-matched conditions near Brain Tumor

Brain Tumor lists 34 open slots (48% of 71 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Brain Tumor on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Brain Tumor is recruiting above its size-band peers.

    34 of 71 indexed trials (47.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Brain Tumor trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 6 of 71 trials (8.5%). 43 distinct sponsors appear on at least one study for this condition label.

  3. Most Brain Tumor trials plan to enrol fewer than 100 people.

    Median target enrolment is 43 among the 70 trials that report a genuine target (sentinel values excluded). 51 of those (72.9%) plan for fewer than 100 participants.

  4. Brain Tumor research is mostly interventional.

    55 interventional and 16 observational studies make up this index (77.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 119Phase 29Phase 32

Open and recent trials

71 total, page 2 of 2

ACTIVE NOT RECRUITING NA 10 participants

MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors

InSightec

NCT00147056

COMPLETED 1,214 participants

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

National Cancer Institute (NCI)

NCT02851706

COMPLETED NA 279 participants

Illness Management and Parental Adjustment to Cancer Treatment

Children's Hospital Medical Center, Cincinnati

NCT02505165

COMPLETED Phase 2 125 participants

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Duke University

NCT00597402

COMPLETED 115 participants

Brain Tumor Patient-Caregiver Congruence, MD Anderson Symptom Inventory-Brain Tumor Module (MDASI-BT)

M.D. Anderson Cancer Center

NCT00748774

COMPLETED NA 90 participants

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Massachusetts General Hospital

NCT01063114

COMPLETED 80 participants

Safety and Feasibility of the Infinity Catheter for Radial Access

Rutgers, The State University of New Jersey

NCT04553549

COMPLETED NA 59 participants

In-Room PET in Proton Radiation Therapy

Massachusetts General Hospital

NCT01228448

COMPLETED NA 59 participants

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

University of Michigan Rogel Cancer Center

NCT02409121

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED 32 participants

C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors

Virginia Commonwealth University

NCT05984667

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 2 25 participants

LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma

Istari Oncology

NCT04479241

COMPLETED Phase 2 25 participants

PPX, Temozolomide, and Concurrent Radiation for Newly Diagnosed Brain Tumors

howard safran

NCT00763750

COMPLETED Phase 1 24 participants

IDH1 Peptide Vaccine for Recurrent Grade II Glioma

Katy Peters, MD, PhD

NCT02193347

COMPLETED Phase 1 15 participants

Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors

University of Florida

NCT01111097

COMPLETED Phase 1 10 participants

Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors

Monteris Medical

NCT00747253

COMPLETED Phase 2 9 participants

GW572016 to Treat Recurrent Malignant Brain Tumors

National Cancer Institute (NCI)

NCT00107003

COMPLETED NA 6 participants

Neurosurgical Use of Interstitial Laser Therapy (ILT)

Brigham and Women's Hospital

NCT00207350

COMPLETED Early Phase 1 5 participants

PET and MRI Imaging of Brain Tumors Using [18F]PARPi

Memorial Sloan Kettering Cancer Center

NCT04173104

COMPLETED Phase 1

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

National Cancer Institute (NCI)

NCT00019630

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Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 9
Phase 3 2

Named interventions

Most-linked intervention names on Brain Tumor records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Temozolomide Drug
4 trials
abemaciclib Drug
2 trials
Intra-arterial Mannitol Drug
2 trials
Intra-arterial Cetuximab Drug
2 trials
proton beam radiation Radiation
1 trials
ESO Other
1 trials
Blood samples obtained Other
1 trials
Neoadjuvant therapy Procedure
1 trials

US sites by state

Facility locations filed on Brain Tumor trials. A trial with sites in several states counts in each.

New York 16 trials
Massachusetts 14 trials
Texas 13 trials
Maryland 9 trials
Florida 9 trials
Ohio 8 trials
North Carolina 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Brain Tumor page

71 registered trials, 34 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Brain Tumor condition card totals 71 registered trials; most-linked intervention Temozolomide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.