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ClinicalTrials.gov 34 recruiting now official registry

Brain Tumor clinical trials

34 of 71 indexed Brain Tumor trials are currently recruiting.

71 US clinical trials · 34 currently recruiting

Brain Tumor is the subject of 71 registered US clinical trials on ClinicalTrials.gov, 34 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 6 of these trials.

The research picture

Brain Tumor has 71 registered US clinical trials, 34 of them open to new participants right now, about 48% of the total.

34
recruiting participants now
48%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
6
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 119Phase 29Phase 32

Active & Recent Trials

71 total, page 2 of 2

ACTIVE NOT RECRUITING NA 10 participants

MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors

InSightec

NCT00147056

COMPLETED 1,214 participants

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

National Cancer Institute (NCI)

NCT02851706

COMPLETED NA 279 participants

Illness Management and Parental Adjustment to Cancer Treatment

Children's Hospital Medical Center, Cincinnati

NCT02505165

COMPLETED Phase 2 125 participants

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Duke University

NCT00597402

COMPLETED 115 participants

Brain Tumor Patient-Caregiver Congruence, MD Anderson Symptom Inventory-Brain Tumor Module (MDASI-BT)

M.D. Anderson Cancer Center

NCT00748774

COMPLETED NA 90 participants

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Massachusetts General Hospital

NCT01063114

COMPLETED 80 participants

Safety and Feasibility of the Infinity Catheter for Radial Access

Rutgers, The State University of New Jersey

NCT04553549

COMPLETED NA 59 participants

In-Room PET in Proton Radiation Therapy

Massachusetts General Hospital

NCT01228448

COMPLETED NA 59 participants

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

University of Michigan Rogel Cancer Center

NCT02409121

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED 32 participants

C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors

Virginia Commonwealth University

NCT05984667

COMPLETED 31 participants

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

St. Jude Children's Research Hospital

NCT01540175

COMPLETED Phase 2 25 participants

LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma

Istari Oncology

NCT04479241

COMPLETED Phase 2 25 participants

PPX, Temozolomide, and Concurrent Radiation for Newly Diagnosed Brain Tumors

howard safran

NCT00763750

COMPLETED Phase 1 24 participants

IDH1 Peptide Vaccine for Recurrent Grade II Glioma

Katy Peters, MD, PhD

NCT02193347

COMPLETED Phase 1 15 participants

Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors

University of Florida

NCT01111097

COMPLETED Phase 1 10 participants

Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors

Monteris Medical

NCT00747253

COMPLETED Phase 2 9 participants

GW572016 to Treat Recurrent Malignant Brain Tumors

National Cancer Institute (NCI)

NCT00107003

COMPLETED NA 6 participants

Neurosurgical Use of Interstitial Laser Therapy (ILT)

Brigham and Women's Hospital

NCT00207350

COMPLETED Early Phase 1 5 participants

PET and MRI Imaging of Brain Tumors Using [18F]PARPi

Memorial Sloan Kettering Cancer Center

NCT04173104

COMPLETED Phase 1

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

National Cancer Institute (NCI)

NCT00019630

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Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 9
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Brain Tumor Trial Landscape

71 indexed Brain Tumor studies · 34 recruiting (48%).

Phase mix: 2 late (III/IV) vs 28 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (6 trials), 9 others listed. 21 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Brain Tumor?

PlainTrial tracks 71 US clinical trials for Brain Tumor, of which 34 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Brain Tumor?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.