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NCT01111097 · ClinicalTrials.gov registry record · Phase 1

Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors

A Phase 1 study of Glioblastoma and Brain Tumor, sponsored by University of Florida.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT01111097 is a Phase 1 study of Glioblastoma and Brain Tumor that has completed, run by University of Florida. The registered enrollment target is 15 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01111097, a Phase 1 study of Glioblastoma and Brain Tumor, has completed, sponsored by University of Florida.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the safety and tolerability of oral Dichloroacetate (DCA) in the treatment of recurrent malignant brain tumors (RMBTs). RMBTs are defined as either: 1) malignant tumors, originating in the brain, that have recurred at least once or 2) malignant tumors originating elsewhere in the body that have spread to the brain at least once. Otherwise, there are no limitations to the number of prior recurrences. There are no limitations to the number or types of prior therapies.

Conditions Studied

Interventions

  • DRUG Dichloroacetate

Study Locations (1)

Florida

  • University of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2010-04
Est. Completion 2014-03
Phase Phase 1

Sponsor

University of Florida

1,106 total trials

What the Registry Record Tells You About NCT01111097

The ClinicalTrials.gov registry entry for NCT01111097 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (86% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Glioblastoma appearing as the primary indexed condition, and to 1 intervention - of which Dichloroacetate is the first listed.

NCT01111097 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT01111097 about?

NCT01111097 is a clinical study titled "Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors". The purpose of this study is to evaluate the safety and tolerability of oral Dichloroacetate (DCA) in the treatment of recurrent malignant brain tumors (RMBTs). RMBTs are defined as either: 1) malignant tumors, originating in the brain, that have recurred at least once or 2) malignant tumors origina...

What is the current status of trial NCT01111097?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2010-04. Estimated completion is 2014-03.

What conditions does trial NCT01111097 study?

This clinical trial studies the following conditions: Glioblastoma, Brain Tumor.

What interventions are being tested in trial NCT01111097?

The interventions under investigation include: Dichloroacetate (DRUG).

Who is sponsoring clinical trial NCT01111097?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01111097 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.