InSightec

38 total trials 8 currently recruiting 19 completed

InSightec sponsors 38 registered US clinical trials on ClinicalTrials.gov, 8 of them currently recruiting, and 19 completed. 4 of these trials are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Essential Tremor, with 3 trials.

Trial Pipeline

38 total, page 1 of 1

RECRUITING

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

NCT05539196

RECRUITING Phase 1

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)

NCT05630209

RECRUITING Phase 3

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

NCT05317858

RECRUITING

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

NCT04991831

RECRUITING NA

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

NCT04197921

RECRUITING NA

ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

NCT03671889

RECRUITING NA

A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects

NCT03028246

RECRUITING

Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic Uterine Fibroids

NCT05386615

ACTIVE NOT RECRUITING NA

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

NCT04728295

ACTIVE NOT RECRUITING NA

Bilateral Treatment of Medication Refractory Essential Tremor

NCT04112381

ACTIVE NOT RECRUITING NA

Continued Access of Focal MR-Guided Focused Ultrasound for Localized Intermediate Risk Prostate Lesions

NCT03998657

ACTIVE NOT RECRUITING NA

ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Parkinson's Disease

NCT03319485

ACTIVE NOT RECRUITING

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

NCT03100474

ACTIVE NOT RECRUITING NA

ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease

NCT02246374

ACTIVE NOT RECRUITING NA

MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors

NCT00147056

COMPLETED NA

Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors

NCT05383872

COMPLETED Phase 1

Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy

NCT04417088

COMPLETED NA

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption

NCT03551249

COMPLETED NA

ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's Disease

NCT02263885

COMPLETED NA

Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors

NCT02289560

COMPLETED NA

Focal MR-Guided Focused Ultrasound Treatment of Localized Intermediate Risk Prostate Lesions

NCT01657942

COMPLETED NA

A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

NCT01833806

TERMINATED

ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

NCT01834937

COMPLETED NA

ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors

NCT01827904

COMPLETED NA

ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Parkinson's Disease

NCT01772693

COMPLETED NA

ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids

NCT01285960

COMPLETED Phase 1

ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor

NCT01304758

COMPLETED NA

Safety Study of ExAblate for the Treatment of Uterine Fibroids

NCT01142791

TERMINATED NA

ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain

NCT00981578

TERMINATED NA

ExAblate Treatment of Uterine Fibroids for Fertility Enhancement

NCT00730886

COMPLETED NA

ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain

NCT00656305

COMPLETED Phase 3

MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication

NCT00365989

COMPLETED Phase 1

MR Guided Focused Ultrasound Surgery of Metastatic Bone Tumors

NCT00350233

COMPLETED Phase 3

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation

NCT00295217

COMPLETED NA

Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids

NCT00131365

COMPLETED NA

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids

NCT00166270

TERMINATED Phase 3

MR Guided Focused Ultrasound Surgery in the Treatment of Breast Fibroadenomas

NCT00147108

COMPLETED Phase 2

MRI-Guided Ultrasound Energy in Treating Patients With Stage I, Stage II, or Stage IIIA Breast Cancer

NCT00008437

What the Pipeline for InSightec Shows

According to the ClinicalTrials.gov registry, InSightec is linked to 38 US clinical trials across every stage of research activity. Of those, 8 studies are currently recruiting, about 21% of the sponsor's indexed portfolio, and 19 are already marked complete, representing roughly 50% of the total.

The phase mix for InSightec reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 5 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for InSightec is Essential Tremor with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.