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Back Pain clinical trials
12 of 38 indexed Back Pain trials are currently recruiting.
38 US clinical trials · 12 currently recruiting
Back Pain is the subject of 38 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 3 of these trials.
The research picture
Back Pain has 38 registered US clinical trials, 12 of them open to new participants right now, about 32% of the total.
- 12
- recruiting participants now
- 32%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Brigham and Women's Hospital
Active & Recent Trials
38 total, page 1 of 1
VIA Disc NP Registry 3.0
VIVEX Biologics
NCT06345690
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Rush University Medical Center
NCT06044649
Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain
University of Minnesota
NCT06696352
CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
Stanford University
NCT06027099
Self-management of Low Back Pain in Horticulture Workers
University of Florida
NCT06153199
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
University of Colorado, Denver
NCT05052541
Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
Vanderbilt University Medical Center
NCT05142267
Cannabidiol for Reduction of Brain Neuroinflammation
Massachusetts General Hospital
NCT05066308
Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department
Western Michigan University School of Medicine
NCT06395428
Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Kuros Biosurgery
NCT04679844
Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques
The University of Texas Medical Branch, Galveston
NCT07112404
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
Alimorad Farshchian
NCT05909709
The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
SPR Therapeutics
NCT04246281
Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain
Northwell Health
NCT01633034
Development of STEPPT
San Diego State University
NCT06835439
Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain
University of Colorado, Denver
NCT05820204
Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
Northwestern University
NCT05463367
Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
Brigham and Women's Hospital
NCT04895306
Strategies for Prescribing Analgesics Comparative Effectiveness Trial
VA Office of Research and Development
NCT01583985
ADAPT: Addressing Depression and Pain Together
University of Pittsburgh
NCT01124188
Evaluation the Impact of the "Pas" Technique Versus the "Standard" Technique on Radiation Exposure
Orthospine Advance Health
NCT06918197
Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS)
SPR Therapeutics
NCT03179202
Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care
ZetrOZ
NCT05254470
Telehealth Outreach for Chronic Back Pain
VA Office of Research and Development
NCT00608530
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
Ortho-McNeil Janssen Scientific Affairs
NCT00771758
Spinal Cord Stimulator Implant Study
Duke University
NCT00887419
Evaluation of Efficacy and Comfort: A Trial on the Incrediwear Back Brace in Patients With Chronic Lower Back Pain
Johns Hopkins University
NCT06126887
Brain Mechanisms of Acupuncture Treatment in Chronic Low Back Pain
Brigham and Women's Hospital
NCT01595451
Combined Interventions for Treating Depression and Chronic Back Pain
Kaiser Permanente
NCT00158275
An Implantable Spinal Cord Stimulation Pain Management System
Boston Scientific Corporation
NCT00205855
Muscle Activation Characteristics During Spinal Manipulation in Healthy and Low Back Pain Participants
University of Denver
NCT03483714
Perioperative ACT for Preventing CPSP: a Single-arm Non-randomized Pilot Trial
Samantha Meints
NCT06750874
Comparison of Activator Manipulation Versus Manual Side Posture Manipulation in Patients With Low Back Pain
Cleveland Chiropractic College
NCT00497861
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Wake Forest University Health Sciences
NCT04156802
Comparing Sports Bra Design in Full Busted Women
University of Houston
NCT05456594
Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery
Brigham and Women's Hospital
NCT06335485
Muscle Activity During Load Carriage in ROTC Cadets
North Dakota State University
NCT04744246
Microbreaks in the OR to Mitigate High Physical and Mental Demands
Mayo Clinic
NCT02565394
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 4 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Back Pain Trial Landscape
38 indexed Back Pain studies · 12 recruiting (32%).
Phase mix: 6 late (III/IV) vs 4 early (I/II).
Top sponsor: Brigham and Women's Hospital (3 trials), 9 others listed. 38 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Back Pain?
PlainTrial tracks 38 US clinical trials for Back Pain, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Back Pain?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.