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Back Pain: full-pipeline trial registry
12 of 38 indexed Back Pain trials are currently recruiting.
Corpus placement: #393 of 28,707 conditions by registered trial count.
38 US clinical trials · 12 currently recruiting · #393 of 28,707 conditions by registered trial count
Back Pain: 38 US clinical trials tracked, 12 recruiting.
Back Pain is the subject of 38 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 3 of these trials.
Enrollment posture brief
Registry condition back-pain
OPEN 12 | RECR 32% | LATE 6 | EARLY 4 | RANK #393 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Breast Adenocarcinoma (32% recruiting · 19 trials)
Back Pain lists 12 open slots (32% of 38 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Back Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Back Pain is recruiting below its size-band peers.
12 of 38 indexed trials (31.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Back Pain trials is spread across many organizations.
Brigham and Women's Hospital accounts for 3 of 38 trials (7.9%). 33 distinct sponsors appear on at least one study for this condition label.
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Typical Back Pain enrolment sits around 101 participants.
Median target enrolment is 101 among the 38 trials that report a genuine target (sentinel values excluded). 18 of those (47.4%) plan for fewer than 100 participants.
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Back Pain research is mostly interventional.
34 interventional and 4 observational studies make up this index (89.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
38 total, page 1 of 1
VIA Disc NP Registry 3.0
VIVEX Biologics
NCT06345690
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Rush University Medical Center
NCT06044649
Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain
University of Minnesota
NCT06696352
CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
Stanford University
NCT06027099
Self-management of Low Back Pain in Horticulture Workers
University of Florida
NCT06153199
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
University of Colorado, Denver
NCT05052541
Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
Vanderbilt University Medical Center
NCT05142267
Cannabidiol for Reduction of Brain Neuroinflammation
Massachusetts General Hospital
NCT05066308
Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department
Western Michigan University School of Medicine
NCT06395428
Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Kuros Biosurgery
NCT04679844
Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques
The University of Texas Medical Branch, Galveston
NCT07112404
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
Alimorad Farshchian
NCT05909709
The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
SPR Therapeutics
NCT04246281
Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain
Northwell Health
NCT01633034
Development of STEPPT
San Diego State University
NCT06835439
Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain
University of Colorado, Denver
NCT05820204
Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
Northwestern University
NCT05463367
Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
Brigham and Women's Hospital
NCT04895306
Strategies for Prescribing Analgesics Comparative Effectiveness Trial
VA Office of Research and Development
NCT01583985
ADAPT: Addressing Depression and Pain Together
University of Pittsburgh
NCT01124188
Evaluation the Impact of the "Pas" Technique Versus the "Standard" Technique on Radiation Exposure
Orthospine Advance Health
NCT06918197
Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS)
SPR Therapeutics
NCT03179202
Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care
ZetrOZ
NCT05254470
Telehealth Outreach for Chronic Back Pain
VA Office of Research and Development
NCT00608530
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
Ortho-McNeil Janssen Scientific Affairs
NCT00771758
Spinal Cord Stimulator Implant Study
Duke University
NCT00887419
Evaluation of Efficacy and Comfort: A Trial on the Incrediwear Back Brace in Patients With Chronic Lower Back Pain
Johns Hopkins University
NCT06126887
Brain Mechanisms of Acupuncture Treatment in Chronic Low Back Pain
Brigham and Women's Hospital
NCT01595451
Combined Interventions for Treating Depression and Chronic Back Pain
Kaiser Permanente
NCT00158275
An Implantable Spinal Cord Stimulation Pain Management System
Boston Scientific Corporation
NCT00205855
Muscle Activation Characteristics During Spinal Manipulation in Healthy and Low Back Pain Participants
University of Denver
NCT03483714
Perioperative ACT for Preventing CPSP: a Single-arm Non-randomized Pilot Trial
Samantha Meints
NCT06750874
Comparison of Activator Manipulation Versus Manual Side Posture Manipulation in Patients With Low Back Pain
Cleveland Chiropractic College
NCT00497861
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Wake Forest University Health Sciences
NCT04156802
Comparing Sports Bra Design in Full Busted Women
University of Houston
NCT05456594
Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery
Brigham and Women's Hospital
NCT06335485
Muscle Activity During Load Carriage in ROTC Cadets
North Dakota State University
NCT04744246
Microbreaks in the OR to Mitigate High Physical and Mental Demands
Mayo Clinic
NCT02565394
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 4 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Back Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Back Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Back Pain page
38 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 12 Back Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Brigham and Women's Hospital sponsors the most Back Pain trials on record, review their full trial history before evaluating a specific study. See Brigham and Women's Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Back Pain condition card totals 38 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.