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NCT05052541 · ClinicalTrials.gov registry record · Phase 3
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
A Phase 3 study of Back Pain and Neck Pain, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 157
- Enrollment target
- 1
- Study location
NCT05052541: Recruiting Phase 3 study of Back Pain and Neck Pain, sponsored by University of Colorado, Denver.
NCT05052541 is a Phase 3 study of Back Pain and Neck Pain that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 157 participants, above the 138-participant average among 37 other Back Pain trials with a reported enrollment target (14% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05052541, a Phase 3 study of Back Pain and Neck Pain, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 157 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy for reducing high-dose opioid use in patients with chronic spine pain.
Primary Outcome
The Visual Analog Scale (VAS) for pain is a 0-100mm visual scale anchored by "no pain" and "worst possible pain".
Interventions
- DRUG Placebo
- DRUG THC/CBD
- DRUG THC
Study Locations (1)
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 157 participants |
| Start Date | 2026-01 |
| Est. Completion | 2027-06 |
| Phase | Phase 3 |
What NCT05052541 shows while recruiting
NCT05052541 is an interventional study that assigns participants to a tested intervention. The registered 157 participants enrollment target is mid-sized for trials with a published cap, above the 138-participant average among 37 other Back Pain trials with a reported enrollment target (14% higher).
The record links to 2 conditions, with Back Pain appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05052541 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT05052541 about?
NCT05052541 is a clinical study titled "Safety and Efficacy of Oral Cannabis in Chronic Spine Pain". The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy for reducing high-dose opioid use in patients with chronic spine pain.
What is the current status of trial NCT05052541?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 157 participants. The study started on 2026-01. Estimated completion is 2027-06.
What conditions does trial NCT05052541 study?
This clinical trial studies the following conditions: Back Pain, Neck Pain.
What interventions are being tested in trial NCT05052541?
The interventions under investigation include: Placebo (DRUG), THC/CBD (DRUG), THC (DRUG).
Who is sponsoring clinical trial NCT05052541?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05052541 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05052541's enrollment target sits among peer trials
157 13th of 37 higher than 25 of 37 other Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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