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NCT05463367 · ClinicalTrials.gov registry record · Phase 2
Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
A Phase 2 study of Chronic Pain and Opioid Use Disorder, sponsored by Northwestern University.
- Active
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05463367 is a Phase 2 study of Chronic Pain and Opioid Use Disorder that is active but no longer recruiting, run by Northwestern University. The registered enrollment target is 60 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05463367, a Phase 2 study of Chronic Pain and Opioid Use Disorder, is active but no longer recruiting, sponsored by Northwestern University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to track brain functional changes in individuals with i) chronic back pain + opioid use (CBP+O) and individuals with ii) chronic back pain + opioid misuse disorder (CBP+mOUD) following a brief drug delay and re-exposure manipulation. Re-exposure could be placebo, the participant's own opioid dose, or a dopaminergic treatment (DA+NSAID). The participants will be also evaluated for changes in cognition, emotion, and motor abilities with opioid delay and re-exposure to placebo, opioid, or DA+NSAID.
Conditions Studied
Interventions
- DRUG Naproxen 500 Mg
- DRUG Opioids
- DRUG Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet
Study Locations (1)
Illinois
- Northwestern University Feinberg School of Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-01-01 |
| Est. Completion | 2025-06-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05463367
The ClinicalTrials.gov registry entry for NCT05463367 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with Chronic Pain appearing as the primary indexed condition, and to 3 interventions - of which Naproxen 500 Mg is the first listed.
NCT05463367 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT05463367 about?
NCT05463367 is a clinical study titled "Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure". This study is designed to track brain functional changes in individuals with i) chronic back pain + opioid use (CBP+O) and individuals with ii) chronic back pain + opioid misuse disorder (CBP+mOUD) following a brief drug delay and re-exposure manipulation. Re-exposure could be placebo, the participa...
What is the current status of trial NCT05463367?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-01-01. Estimated completion is 2025-06-01.
What conditions does trial NCT05463367 study?
This clinical trial studies the following conditions: Chronic Pain, Opioid Use Disorder, Opioid Use, Chronic Low Back Pain, Pain, Chronic.
What interventions are being tested in trial NCT05463367?
The interventions under investigation include: Naproxen 500 Mg (DRUG), Opioids (DRUG), Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT05463367?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05463367 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.