Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06027099 · ClinicalTrials.gov registry record · Phase 3

CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial

A Phase 3 study of Chronic Pain and Back Pain, sponsored by Stanford University.

Recruiting
Registry status
Phase 3
Development phase
375
Enrollment target
1
Study location

NCT06027099 is a Phase 3 study of Chronic Pain and Back Pain that is actively recruiting participants, run by Stanford University. The registered enrollment target is 375 participants, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06027099, a Phase 3 study of Chronic Pain and Back Pain, is actively recruiting participants, sponsored by Stanford University.

RECRUITING
Registry status
Phase 3
Development phase
375 participants
Enrollment target
1
Study location

Study Summary

Three-arm randomized controlled trial, of Motivational Interviewing and guided Opioid Tapering support (MI-Opioid Taper) and tizanidine vs. MI-Opioid Taper and placebo vs. enhanced usual care to promote postoperative opioid cessation and pain cessation and reduce the incidence of postoperative opioid misuse among patients undergoing spine surgery.

Conditions Studied

Chronic Pain Back Pain Neck Pain Opioid Misuse

Interventions

  • DRUG Placebo
  • BEHAVIORAL Enhanced Usual Care
  • DRUG Tizanidine
  • BEHAVIORAL MI-Opioid Taper

Study Locations (1)

California

  • Stanford University Hospital - Stanford

Trial Details

FieldValue
Enrollment Target 375 participants
Start Date 2024-12-05
Est. Completion 2028-07
Phase Phase 3

Sponsor

Stanford University

1,744 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06027099

The ClinicalTrials.gov registry entry for NCT06027099 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 375 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (51% lower). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Chronic Pain appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT06027099 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06027099 about?

NCT06027099 is a clinical study titled "CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial". Three-arm randomized controlled trial, of Motivational Interviewing and guided Opioid Tapering support (MI-Opioid Taper) and tizanidine vs. MI-Opioid Taper and placebo vs. enhanced usual care to promote postoperative opioid cessation and pain cessation and reduce the incidence of postoperative opioi...

What is the current status of trial NCT06027099?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 375 participants. The study started on 2024-12-05. Estimated completion is 2028-07.

What conditions does trial NCT06027099 study?

This clinical trial studies the following conditions: Chronic Pain, Back Pain, Neck Pain, Opioid Misuse.

What interventions are being tested in trial NCT06027099?

The interventions under investigation include: Placebo (DRUG), Enhanced Usual Care (BEHAVIORAL), Tizanidine (DRUG), MI-Opioid Taper (BEHAVIORAL).

Who is sponsoring clinical trial NCT06027099?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06027099 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Chronic Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Chronic Pain

All registered trials for this condition

Back Pain

All registered trials for this condition

California

All trials with a study site in California

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.