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NCT06977178 · ClinicalTrials.gov registry record · NA

Adverse Adolescent Pathways to Substance Use

A NA study of Anxiety and Substance Use, sponsored by University of North Carolina, Chapel Hill.

Recruiting
Registry status
NA
Development phase
180
Enrollment target
1
Study location

NCT06977178: Recruiting NA study of Anxiety and Substance Use, sponsored by University of North Carolina, Chapel Hill.

NCT06977178 is a NA study of Anxiety and Substance Use that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 180 participants, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06977178, a NA study of Anxiety and Substance Use, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.

RECRUITING
Registry status
NA
Development phase
180 participants
Enrollment target
1
Study location

Study Summary

Purpose: This 5-year R01 study will elucidate the role of maturational change across adolescence in neural connectivity and physiological stress responses in the relationship between anxiety and adverse pathways to substance use (APSU). Participants: Children (N=200) aged 12-14 with symptoms of anxiety and their legal caregiver will be recruited from clinical and community sources. Procedures: Youth participants will complete several questionnaires and interviews, undergo neuroimaging while performing cognitive tasks, and have their heart rate and skin conductance monitored during a mildly stressful task. Caregivers will complete several questionnaires.

Primary Outcome

The Stop Signal Task is a measure of inhibitory control. Participants are presented with a right or left arrow and instructed to press one of two buttons corresponding with each arrow after it is presented. However, on certain trials, there is an up facing arrow immediately following the presentation of a left or right arrow, and participants are instructed to not press any buttons if they see an up arrow. The task measures the mean go reaction time to evaluate the participant's ability to inhib

Conditions Studied

Anxiety Substance Use Adolescent Development

Interventions

  • BEHAVIORAL Trier Social Stress Test

Study Locations (1)

North Carolina

  • The University of North Carolina at Chapel Hill School of Medicine - Chapel Hill

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2024-02-20
Est. Completion 2030-06-30
Phase NA
University of North Carolina, Chapel Hill

1,109 total trials

What NCT06977178 shows while recruiting

NCT06977178 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (59% lower).

The record links to 3 conditions, with Anxiety appearing as the primary indexed condition, and to 1 intervention - of which Trier Social Stress Test is the first listed.

NCT06977178 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT06977178 about?

NCT06977178 is a clinical study titled "Adverse Adolescent Pathways to Substance Use". Purpose: This 5-year R01 study will elucidate the role of maturational change across adolescence in neural connectivity and physiological stress responses in the relationship between anxiety and adverse pathways to substance use (APSU). Participants: Children (N=200) aged 12-14 with symptoms of anxi...

What is the current status of trial NCT06977178?

This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2024-02-20. Estimated completion is 2030-06-30.

What conditions does trial NCT06977178 study?

This clinical trial studies the following conditions: Anxiety, Substance Use, Adolescent Development.

What interventions are being tested in trial NCT06977178?

The interventions under investigation include: Trier Social Stress Test (BEHAVIORAL).

Who is sponsoring clinical trial NCT06977178?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06977178 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Anxiety

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06977178's enrollment target sits among peer trials

180 94th of 364 higher than 269 of 364 other Anxiety trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anxiety trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06977178

Source: ClinicalTrials.gov NCT06977178, the US trial registry maintained by the National Library of Medicine. NCT06977178 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.