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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 2 of 8

RECRUITING NA 150 participants

Radiotherapy Patient Education With Virtual Reality

University of Miami

NCT06506435

RECRUITING NA 150 participants

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

Medical University of South Carolina

NCT07390786

RECRUITING NA 150 participants

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

University of Pittsburgh

NCT05658796

RECRUITING NA 150 participants

Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders

Viome

NCT06502717

RECRUITING NA 150 participants

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

Medical University of South Carolina

NCT07372586

RECRUITING Phase 2 146 participants

Behavioral Exposure for Introceptive Tolerance RCT

Rutgers, The State University of New Jersey

NCT05398276

RECRUITING NA 140 participants

Test of Target Engagement of Ambiguity Aversion

Northwestern University

NCT06962527

RECRUITING NA 139 participants

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Baylor College of Medicine

NCT06537128

RECRUITING Phase 4 132 participants

Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)

University of Cincinnati

NCT04623099

RECRUITING NA 120 participants

SilverCloud as a School-Based Intervention for Vulnerable Youth

NYU Langone Health

NCT06004414

RECRUITING NA 120 participants

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

Yale University

NCT05810259

RECRUITING NA 118 participants

Just-in-Time Training for Youth Mentors

University of Minnesota

NCT07129070

RECRUITING NA 110 participants

Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4

University of Michigan

NCT06563310

RECRUITING NA 110 participants

Developing Resilience and Anxiety Management Through the Arts

Case Western Reserve University

NCT07033052

RECRUITING Phase 2 108 participants

Pramipexole to Enhance Social Connections

University of California, San Diego

NCT06269146

RECRUITING NA 106 participants

Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care

Portland State University

NCT06019377

RECRUITING NA 106 participants

Music Use in Parturients Admitted to Labor & Delivery

Tufts Medical Center

NCT06969105

RECRUITING NA 100 participants

Social Support and Reduced Fear Acquisition

University of California, Los Angeles

NCT04564976

RECRUITING Phase 2 100 participants

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

NCT06899165

RECRUITING NA 100 participants

Randomized Controlled Trial of a Behavioral Training App

New York University

NCT06447909

RECRUITING NA 100 participants

Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)

Northwestern University

NCT05942469

RECRUITING NA 100 participants

Social Support and Enhanced Fear Extinction

University of California, Los Angeles

NCT04565041

RECRUITING NA 100 participants

Pilot Study of Virtual Reality Therapy for Students With Anxiety

The University of Texas Health Science Center, Houston

NCT05319509

RECRUITING NA 100 participants

Amplification of Positivity for Alcohol Use

Laureate Institute for Brain Research

NCT06030154

RECRUITING NA 100 participants

Uncertainty and Firearms: Obtaining Secure Storage

Ohio State University

NCT05818696

RECRUITING NA 100 participants

Virtual Patient Groups for Sarcoidosis Associated Fatigue

The Cleveland Clinic

NCT07073963

RECRUITING NA 96 participants

Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons

University of Wisconsin, Madison

NCT06162624

RECRUITING NA 95 participants

Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population

Boston University Charles River Campus

NCT04895995

RECRUITING NA 90 participants

Mobile Mental Health Stigma Reduction Intervention Among Black Adults

Massachusetts General Hospital

NCT06316804

RECRUITING Phase 4 90 participants

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

University of Oklahoma

NCT05934669

RECRUITING NA 85 participants

Expressive Writing on Minority Stressors Among Sexual Minority Veterans

VA Office of Research and Development

NCT05897021

RECRUITING NA 85 participants

Neurobiological Mechanisms of Aging and Stress on Prospective Navigation

Georgia Institute of Technology

NCT03896529

RECRUITING NA 84 participants

Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

Massachusetts General Hospital

NCT07143357

RECRUITING NA 80 participants

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

Boston Medical Center

NCT06812247

RECRUITING NA 80 participants

Stress Management Program

Stanford University

NCT06526585

RECRUITING NA 80 participants

Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners

University of Michigan

NCT06324383

RECRUITING 80 participants

Potential Benefits of Parent Child Interaction Therapy (PCIT)

University of Florida

NCT06827951

RECRUITING NA 80 participants

The Role of Virtual Reality During Regional Anesthesia

Cedars-Sinai Medical Center

NCT04163809

RECRUITING Phase 2 75 participants

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

University of California, Los Angeles

NCT06073886

RECRUITING 75 participants

Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series

Reset Medical and Wellness Center

NCT07473505

RECRUITING NA 74 participants

Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families

University of Illinois at Chicago

NCT06261463

RECRUITING Early Phase 1 70 participants

Sleep, Dreaming, and Virtual Reality for Mental Health

Northwestern University

NCT07408206

RECRUITING NA 66 participants

Music-Based Interventions, Aging, Alzheimer's Disease

University of Southern California

NCT06152211

RECRUITING NA 64 participants

Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures

Northwestern University

NCT05744336

RECRUITING NA 64 participants

Improving Minority Health Through Biofeedback and Stress Reduction

Amelia Saul, PhD, CTRS, BCB

NCT07172152

RECRUITING NA 62 participants

Effects of Virtual Reality Relaxation on the Anxiety Levels

Indiana University

NCT06804967

RECRUITING Phase 4 60 participants

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

University of Cincinnati

NCT04245436

RECRUITING NA 60 participants

Managing Anxiety in Pediatric Primary Care (MAPP)

UConn Health

NCT06104904

RECRUITING NA 60 participants

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

University of Florida

NCT07112001

RECRUITING NA 60 participants

Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities

Montclair State University

NCT06904508

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.