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Anxiety clinical trials
148 of 367 indexed Anxiety trials are currently recruiting.
367 US clinical trials · 148 currently recruiting
Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.
The research picture
Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.
- 148
- recruiting participants now
- 40%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 11
- top sponsor: University of California, Los Angeles
Active & Recent Trials
367 total, page 2 of 8
Radiotherapy Patient Education With Virtual Reality
University of Miami
NCT06506435
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
Medical University of South Carolina
NCT07390786
RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty
University of Pittsburgh
NCT05658796
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders
Viome
NCT06502717
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Medical University of South Carolina
NCT07372586
Behavioral Exposure for Introceptive Tolerance RCT
Rutgers, The State University of New Jersey
NCT05398276
Test of Target Engagement of Ambiguity Aversion
Northwestern University
NCT06962527
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Baylor College of Medicine
NCT06537128
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
University of Cincinnati
NCT04623099
SilverCloud as a School-Based Intervention for Vulnerable Youth
NYU Langone Health
NCT06004414
Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life
Yale University
NCT05810259
Just-in-Time Training for Youth Mentors
University of Minnesota
NCT07129070
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
University of Michigan
NCT06563310
Developing Resilience and Anxiety Management Through the Arts
Case Western Reserve University
NCT07033052
Pramipexole to Enhance Social Connections
University of California, San Diego
NCT06269146
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
Portland State University
NCT06019377
Music Use in Parturients Admitted to Labor & Delivery
Tufts Medical Center
NCT06969105
Social Support and Reduced Fear Acquisition
University of California, Los Angeles
NCT04564976
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
NCT06899165
Randomized Controlled Trial of a Behavioral Training App
New York University
NCT06447909
Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)
Northwestern University
NCT05942469
Social Support and Enhanced Fear Extinction
University of California, Los Angeles
NCT04565041
Pilot Study of Virtual Reality Therapy for Students With Anxiety
The University of Texas Health Science Center, Houston
NCT05319509
Amplification of Positivity for Alcohol Use
Laureate Institute for Brain Research
NCT06030154
Uncertainty and Firearms: Obtaining Secure Storage
Ohio State University
NCT05818696
Virtual Patient Groups for Sarcoidosis Associated Fatigue
The Cleveland Clinic
NCT07073963
Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons
University of Wisconsin, Madison
NCT06162624
Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population
Boston University Charles River Campus
NCT04895995
Mobile Mental Health Stigma Reduction Intervention Among Black Adults
Massachusetts General Hospital
NCT06316804
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
University of Oklahoma
NCT05934669
Expressive Writing on Minority Stressors Among Sexual Minority Veterans
VA Office of Research and Development
NCT05897021
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Georgia Institute of Technology
NCT03896529
Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest
Massachusetts General Hospital
NCT07143357
Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries
Boston Medical Center
NCT06812247
Stress Management Program
Stanford University
NCT06526585
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
University of Michigan
NCT06324383
Potential Benefits of Parent Child Interaction Therapy (PCIT)
University of Florida
NCT06827951
The Role of Virtual Reality During Regional Anesthesia
Cedars-Sinai Medical Center
NCT04163809
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
University of California, Los Angeles
NCT06073886
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
Reset Medical and Wellness Center
NCT07473505
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
University of Illinois at Chicago
NCT06261463
Sleep, Dreaming, and Virtual Reality for Mental Health
Northwestern University
NCT07408206
Music-Based Interventions, Aging, Alzheimer's Disease
University of Southern California
NCT06152211
Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures
Northwestern University
NCT05744336
Improving Minority Health Through Biofeedback and Stress Reduction
Amelia Saul, PhD, CTRS, BCB
NCT07172152
Effects of Virtual Reality Relaxation on the Anxiety Levels
Indiana University
NCT06804967
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)
University of Cincinnati
NCT04245436
Managing Anxiety in Pediatric Primary Care (MAPP)
UConn Health
NCT06104904
A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression
University of Florida
NCT07112001
Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities
Montclair State University
NCT06904508
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 25 |
| Phase 3 | 6 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Trial Landscape
367 indexed Anxiety studies · 148 recruiting (40%).
Phase mix: 15 late (III/IV) vs 38 early (I/II).
Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety?
PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.